Page last updated: 2024-11-05

vigabatrin and Stroke

vigabatrin has been researched along with Stroke in 3 studies

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
" Stroke and infarct have a better outcome than other etiologies, whereas Down syndrome might not respond to the addition of vigabatrin to hormonal treatment."3.91The underlying etiology of infantile spasms (West syndrome): Information from the International Collaborative Infantile Spasms Study (ICISS). ( Dietrich Alber, F; Edwards, SW; Hancock, E; Johnson, AL; Kennedy, CR; Likeman, M; Lux, AL; Mackay, M; Mallick, A; Newton, RW; Nolan, M; O'Callaghan, FJK; Osborne, JP; Pressler, R; Rating, D; Schmitt, B; Verity, CM, 2019)
" Furthermore, most preclinical antiepileptogenic studies lack information needed for translation, such as dose-blood level relationship, brain target engagement, and dose-response, and many use treatment parameters that cannot be applied clinically, for example, treatment initiation before or at the time of injury and dosing higher than tolerated human equivalent dosing."2.66Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy? ( Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M, 2020)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Osborne, JP1
Edwards, SW1
Dietrich Alber, F1
Hancock, E1
Johnson, AL1
Kennedy, CR1
Likeman, M1
Lux, AL1
Mackay, M1
Mallick, A1
Newton, RW1
Nolan, M1
Pressler, R1
Rating, D1
Schmitt, B1
Verity, CM1
O'Callaghan, FJK1
Klein, P1
Friedman, A1
Hameed, MQ1
Kaminski, RM1
Bar-Klein, G1
Klitgaard, H1
Koepp, M1
Jozwiak, S1
Prince, DA1
Rotenberg, A1
Twyman, R1
Vezzani, A1
Wong, M1
Löscher, W1
Madden, K1
Clark, W1
Lessov, N1

Reviews

1 review available for vigabatrin and Stroke

ArticleYear
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
    Epilepsia, 2020, Volume: 61, Issue:3

    Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Cef

2020

Other Studies

2 other studies available for vigabatrin and Stroke

ArticleYear
The underlying etiology of infantile spasms (West syndrome): Information from the International Collaborative Infantile Spasms Study (ICISS).
    Epilepsia, 2019, Volume: 60, Issue:9

    Topics: Anticonvulsants; Female; Humans; Infant; Male; Malformations of Cortical Development; Prednisolone;

2019
Failure of ischemic neuroprotection by potentiators of gamma-aminobutyric acid.
    Clinical medicine & research, 2003, Volume: 1, Issue:2

    Topics: Animals; Anticonvulsants; Brain Ischemia; Disease Models, Animal; Fructose; gamma-Aminobutyric Acid;

2003