vigabatrin has been researched along with Schizophrenia in 4 studies
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Proline dehydrogenase (PRODH), which degrades L-proline, resides within the schizophrenia-linked 22q11." | 3.83 | Cytosolic Accumulation of L-Proline Disrupts GABA-Ergic Transmission through GAD Blockade. ( Crabtree, GW; Gogos, JA; Gordon, JA; Park, AJ, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crabtree, GW | 1 |
| Park, AJ | 1 |
| Gordon, JA | 1 |
| Gogos, JA | 1 |
| Gale, K | 1 |
| Casu, M | 1 |
| Korsgaard, S | 1 |
| Casey, DE | 1 |
| Gerlach, J | 1 |
| Thaker, GK | 1 |
| Tamminga, CA | 1 |
| Alphs, LD | 1 |
| Lafferman, J | 1 |
| Ferraro, TN | 1 |
| Hare, TA | 1 |
1 review available for vigabatrin and Schizophrenia
| Article | Year |
|---|---|
Dynamic utilization of GABA in substantia nigra: regulation by dopamine and GABA in the striatum, and its clinical and behavioral implications.
Topics: 4-Aminobutyrate Transaminase; Afferent Pathways; Aminocaproates; Animals; Basal Ganglia; Behavior, A | 1981 |
1 trial available for vigabatrin and Schizophrenia
| Article | Year |
|---|---|
Brain gamma-aminobutyric acid abnormality in tardive dyskinesia. Reduction in cerebrospinal fluid GABA levels and therapeutic response to GABA agonist treatment.
Topics: Adult; Aminocaproates; Brain; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induce | 1987 |
2 other studies available for vigabatrin and Schizophrenia
| Article | Year |
|---|---|
Cytosolic Accumulation of L-Proline Disrupts GABA-Ergic Transmission through GAD Blockade.
Topics: Animals; Central Nervous System; Cytosol; Disease Models, Animal; Gamma Rhythm; gamma-Aminobutyric A | 2016 |
Effect of gamma-vinyl GABA in tardive dyskinesia.
Topics: Adult; Aged; Aminocaproates; Antipsychotic Agents; Dyskinesia, Drug-Induced; Humans; Male; Middle Ag | 1983 |