vigabatrin has been researched along with Optic Atrophy in 7 studies
Optic Atrophy: Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the RETINA and converge to form the OPTIC DISK; OPTIC NERVE; OPTIC CHIASM; and optic tracts. GLAUCOMA; ISCHEMIA; inflammation, a chronic elevation of intracranial pressure, toxins, optic nerve compression, and inherited conditions (see OPTIC ATROPHIES, HEREDITARY) are relatively common causes of this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report the discovery of a previously unknown form of optic atrophy associated with use of the anti-epileptic drug vigabatrin." | 7.72 | Characterization of vigabatrin-associated optic atrophy. ( Frisén, L; Malmgren, K, 2003) |
| "To describe the clinical pattern of retinal atrophy in children caused by the anticonvulsant vigabatrin." | 7.72 | Characteristic retinal atrophy with secondary "inverse" optic atrophy identifies vigabatrin toxicity in children. ( Buncic, JR; Logan, WJ; MacKeen, LD; Munn, JR; Panton, CM; Westall, CA, 2004) |
| "Vigabatrin dose was 25-114 mg/kg/day (mean 55." | 5.31 | Vigabatrin associated retinal dysfunction in children with epilepsy. ( Al Riyami, K; Bulusu, S; Chacko, A; Ganesh, A; Koul, R, 2001) |
| "To describe the clinical pattern of retinal atrophy in children caused by the anticonvulsant vigabatrin." | 3.72 | Characteristic retinal atrophy with secondary "inverse" optic atrophy identifies vigabatrin toxicity in children. ( Buncic, JR; Logan, WJ; MacKeen, LD; Munn, JR; Panton, CM; Westall, CA, 2004) |
| "Vigabatrin is an antiepileptic drug and may increase the intraretinal GABA level due to an inhibition of the enzyme GABA-transaminase and may induce an ascending simple optic nerve atrophy." | 1.32 | [Vigabatrin-associated bilateral simple optic nerve atrophy with visual field constriction. A case report and a survey of the literature]. ( Mardin, CY; Viestenz, A, 2003) |
| "Vigabatrin dose was 25-114 mg/kg/day (mean 55." | 1.31 | Vigabatrin associated retinal dysfunction in children with epilepsy. ( Al Riyami, K; Bulusu, S; Chacko, A; Ganesh, A; Koul, R, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jammoul, F | 1 |
| Dégardin, J | 1 |
| Pain, D | 1 |
| Gondouin, P | 1 |
| Simonutti, M | 1 |
| Dubus, E | 1 |
| Caplette, R | 1 |
| Fouquet, S | 1 |
| Craft, CM | 1 |
| Sahel, JA | 1 |
| Picaud, S | 1 |
| Viestenz, A | 2 |
| Mardin, CY | 1 |
| Frisén, L | 1 |
| Malmgren, K | 1 |
| Buncic, JR | 1 |
| Westall, CA | 1 |
| Panton, CM | 1 |
| Munn, JR | 1 |
| MacKeen, LD | 1 |
| Logan, WJ | 1 |
| Rebolleda, G | 1 |
| García Pérez, JL | 1 |
| Muñoz Negrete, FJ | 1 |
| Tang, RA | 1 |
| Mennel, S | 1 |
| Schulze, S | 1 |
| Meyer, CH | 1 |
| Koul, R | 1 |
| Chacko, A | 1 |
| Ganesh, A | 1 |
| Bulusu, S | 1 |
| Al Riyami, K | 1 |
7 other studies available for vigabatrin and Optic Atrophy
| Article | Year |
|---|---|
Taurine deficiency damages photoreceptors and retinal ganglion cells in vigabatrin-treated neonatal rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Cell Count; Cell Death; Electroret | 2010 |
[Vigabatrin-associated bilateral simple optic nerve atrophy with visual field constriction. A case report and a survey of the literature].
Topics: Aged; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Evoked Potentials, | 2003 |
Characterization of vigabatrin-associated optic atrophy.
Topics: Anticonvulsants; Dose-Response Relationship, Drug; Fundus Oculi; Humans; Image Processing, Computer- | 2003 |
Characteristic retinal atrophy with secondary "inverse" optic atrophy identifies vigabatrin toxicity in children.
Topics: Adolescent; Anticonvulsants; Atrophy; Child; Electroretinography; Female; Humans; Infant; Male; Opti | 2004 |
Vigabatrin toxicity in children.
Topics: Anticonvulsants; Atrophy; Child; Diagnostic Techniques, Ophthalmological; Humans; Optic Atrophy; Ret | 2005 |
[Asymptomatic concentric visual field deficits and optic nerve atrophy].
Topics: Anticonvulsants; Humans; Male; Middle Aged; Optic Atrophy; Vigabatrin; Vision Disorders; Visual Fiel | 2006 |
Vigabatrin associated retinal dysfunction in children with epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Evoked Po | 2001 |