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vigabatrin and Nervous System Disorders

vigabatrin has been researched along with Nervous System Disorders in 10 studies

Research Excerpts

ExcerptRelevanceReference
"Vigabatrin (Sabril, Hoechst Marion Roussel) is an antiepilepsy drug (AED) presently marketed in 64 countries for the treatment of partial and secondarily generalized seizures."8.80The potential for vigabatrin-induced intramyelinic edema in humans. ( Brigell, MG; Cohen, JA; Fisher, RS; Peyster, RG; Sze, G, 2000)
"Compared with placebo, vigabatrin subjects had a higher incidence of events coded as depression (12."4.80Psychiatric adverse events during vigabatrin therapy. ( Devinsky, O; Levinson, DF, 1999)
"Vigabatrin (Sabril, Hoechst Marion Roussel) is an antiepilepsy drug (AED) presently marketed in 64 countries for the treatment of partial and secondarily generalized seizures."4.80The potential for vigabatrin-induced intramyelinic edema in humans. ( Brigell, MG; Cohen, JA; Fisher, RS; Peyster, RG; Sze, G, 2000)
"Vigabatrin was designed to increase the levels of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in the brain."2.39A risk-benefit assessment of vigabatrin in the treatment of neurological disorders. ( Richens, A; Srinivasan, J, 1994)
" Adverse effects of antiepileptic treatment may affect the patient's quality of life to an even greater extent than the occurrence of seizures."2.39Adverse effects of established and new antiepileptic drugs: an attempted comparison. ( Gram, L; Rogvi-Hansen, B, 1995)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's5 (50.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moskowitz, A1
Hansen, RM1
Eklund, SE1
Fulton, AB1
Uziel, G1
Bardelli, P1
Pantaleoni, C1
Rimoldi, M1
Savoiardo, M1
Rahbeeni, Z1
Ozand, PT1
Rashed, M1
Gascon, GG1
al Nasser, M1
al Odaib, A1
Amoudi, M1
Nester, M1
al Garawi, S1
Brismar, J1
Srinivasan, J1
Richens, A1
Rogvi-Hansen, B1
Gram, L1
Levinson, DF1
Devinsky, O1
Cohen, JA1
Fisher, RS1
Brigell, MG1
Peyster, RG1
Sze, G1
Lenicque, PM1
Wepierre, J1
Cohen, Y1
Armijo, JA1
Graham, D1

Reviews

4 reviews available for vigabatrin and Nervous System Disorders

ArticleYear
A risk-benefit assessment of vigabatrin in the treatment of neurological disorders.
    Drug safety, 1994, Volume: 10, Issue:5

    Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Child; Clinical Trials as Topic; Doub

1994
Adverse effects of established and new antiepileptic drugs: an attempted comparison.
    Pharmacology & therapeutics, 1995, Volume: 68, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; gamma-Aminobutyric Acid; Gastrointestinal Disease

1995
Psychiatric adverse events during vigabatrin therapy.
    Neurology, 1999, Oct-22, Volume: 53, Issue:7

    Topics: Anticonvulsants; Depression; Double-Blind Method; Humans; Incidence; Mental Disorders; Nervous Syste

1999
The potential for vigabatrin-induced intramyelinic edema in humans.
    Epilepsia, 2000, Volume: 41, Issue:2

    Topics: Animals; Anticonvulsants; Brain; Brain Diseases; Clinical Trials as Topic; Dogs; Edema; Epilepsy; Ev

2000

Other Studies

6 other studies available for vigabatrin and Nervous System Disorders

ArticleYear
Electroretinographic (ERG) responses in pediatric patients using vigabatrin.
    Documenta ophthalmologica. Advances in ophthalmology, 2012, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Electroretinography; Humans; Infant; Mi

2012
4-Hydroxybutyric aciduria: clinical findings and vigabatrin therapy.
    Journal of inherited metabolic disease, 1993, Volume: 16, Issue:3

    Topics: Aldehyde Oxidoreductases; Anticonvulsants; Child; Female; gamma-Aminobutyric Acid; Gas Chromatograph

1993
4-Hydroxybutyric aciduria.
    Brain & development, 1994, Volume: 16 Suppl

    Topics: Adult; Anticonvulsants; Brain; Child; Child, Preschool; Dextromethorphan; Female; gamma-Aminobutyric

1994
Protection by 4-amino-hex-5-enoic acid (gamma-vinyl GABA) and hypobaric hypoxia against kainic acid neurotoxicity.
    Psychopharmacology, 1979, Volume: 66, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Atmospheric Pressure; Behavior, Animal; Drink

1979
4-aminobutyrate-2-ketoglutarate aminotransferase (GABA-T) in human hair follicle.
    Revista espanola de fisiologia, 1989, Volume: 45, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Adult; Aminocaproates; Aminooxyacetic Acid; Clinical Enzyme Tests; gam

1989
Neuropathology of vigabatrin.
    British journal of clinical pharmacology, 1989, Volume: 27 Suppl 1

    Topics: Aminocaproates; Animals; Anticonvulsants; Brain; Dogs; Humans; Macaca fascicularis; Mice; Nervous Sy

1989