vigabatrin has been researched along with Hyperactivity, Motor in 3 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vigabatrin (VGB) has demonstrated high efficacy in infantile spasms (IS) due to tuberous sclerosis." | 7.70 | Mental and behavioural outcome of infantile epilepsy treated by vigabatrin in tuberous sclerosis patients. ( Chiron, C; Dulac, O; Dumas, C; Jambaqué, I; Mumford, J, 2000) |
| "Vigabatrin (VGB) has demonstrated high efficacy in infantile spasms (IS) due to tuberous sclerosis." | 3.70 | Mental and behavioural outcome of infantile epilepsy treated by vigabatrin in tuberous sclerosis patients. ( Chiron, C; Dulac, O; Dumas, C; Jambaqué, I; Mumford, J, 2000) |
| "Three large studies, all including more than 60 children, on the efficacy on gamma-vinyl GABA (vigabatrin, GVG) in the treatment of childhood epilepsy have been reviewed." | 3.68 | Treatment of pediatric epilepsies with gamma-vinyl GABA (vigabatrin). ( Dulac, O; Gram, L; Sabers, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jambaqué, I | 1 |
| Chiron, C | 1 |
| Dumas, C | 1 |
| Mumford, J | 1 |
| Dulac, O | 2 |
| Gram, L | 1 |
| Sabers, A | 1 |
| Jongsma, MJ | 1 |
| Laan, LA | 1 |
| van Emde Boas, W | 1 |
| Meinardi, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prednisolone vs. Vigabatrin in the First-line Treatment of Infantile Spasms[NCT02299115] | Phase 3 | 0 participants (Actual) | Interventional | 2017-09-05 | Withdrawn (stopped due to Most centres are now using oral steroids as 1st line treatment so question of efficacy is no longer of high interest.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for vigabatrin and Hyperactivity, Motor
| Article | Year |
|---|---|
Mental and behavioural outcome of infantile epilepsy treated by vigabatrin in tuberous sclerosis patients.
Topics: Anticonvulsants; Autistic Disorder; Child Behavior Disorders; Cognition Disorders; Drug Therapy, Com | 2000 |
Treatment of pediatric epilepsies with gamma-vinyl GABA (vigabatrin).
Topics: Age Factors; Aminocaproates; Anticonvulsants; Child; Child, Preschool; Drug Administration Schedule; | 1992 |
Reversible motor disturbances induced by vigabatrin.
Topics: Adolescent; Aminocaproates; Anticonvulsants; Epilepsy; Female; Humans; Hyperkinesis; Infant; Laughte | 1991 |