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vigabatrin and Fetal Growth Restriction

vigabatrin has been researched along with Fetal Growth Restriction in 3 studies

Research Excerpts

ExcerptRelevanceReference
"Vigabatrin (VGB) has several therapeutic advantages over older antiepileptic drugs (AED), but there is a lack of information about its potential reproductive toxicologic effects."5.36Vigabatrin (VGB) administered during late gestation lowers maternal folate concentration and causes pregnancy loss, fetal growth restriction and skeletal hypoplasia in the mouse. ( Abdulrazzaq, YM; Bastaki, SM; Nurulain, M; Padmanabhan, R; Shafiullah, M, 2010)
"Vigabatrin (VGB) has several therapeutic advantages over older antiepileptic drugs (AED), but there is a lack of information about its potential reproductive toxicologic effects."1.36Vigabatrin (VGB) administered during late gestation lowers maternal folate concentration and causes pregnancy loss, fetal growth restriction and skeletal hypoplasia in the mouse. ( Abdulrazzaq, YM; Bastaki, SM; Nurulain, M; Padmanabhan, R; Shafiullah, M, 2010)
"Vigabatrin (VGB) is a relatively recently introduced antiepileptic drug that enhances the brain levels of gamma aminobutyric acid (GABA)."1.30Teratogenic effects of vigabatrin in TO mouse fetuses. ( Abdulrazzaq, YM; Bastaki, SM; Padmanabhan, R, 1997)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Padmanabhan, R3
Abdulrazzaq, YM3
Bastaki, SM3
Nurulain, M1
Shafiullah, M1
Shafiullah, MM1

Other Studies

3 other studies available for vigabatrin and Fetal Growth Restriction

ArticleYear
Vigabatrin (VGB) administered during late gestation lowers maternal folate concentration and causes pregnancy loss, fetal growth restriction and skeletal hypoplasia in the mouse.
    Reproductive toxicology (Elmsford, N.Y.), 2010, Volume: 29, Issue:3

    Topics: Animals; Anticonvulsants; Bone and Bones; Dietary Supplements; Embryonic Development; Female; Fetal

2010
Intrauterine growth restriction and skeletal variations in mouse fetuses induced by vigabatrin administered at preimplantation stages of development.
    Congenital anomalies, 2008, Volume: 48, Issue:1

    Topics: Animals; Anticonvulsants; Bone and Bones; Embryonic Development; Female; Fetal Growth Retardation; L

2008
Teratogenic effects of vigabatrin in TO mouse fetuses.
    Teratology, 1997, Volume: 55, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Bone and Bones; Embryo Loss; Fetal Growth Ret

1997