vigabatrin has been researched along with Fetal Growth Restriction in 3 studies
Excerpt | Relevance | Reference |
---|---|---|
"Vigabatrin (VGB) has several therapeutic advantages over older antiepileptic drugs (AED), but there is a lack of information about its potential reproductive toxicologic effects." | 5.36 | Vigabatrin (VGB) administered during late gestation lowers maternal folate concentration and causes pregnancy loss, fetal growth restriction and skeletal hypoplasia in the mouse. ( Abdulrazzaq, YM; Bastaki, SM; Nurulain, M; Padmanabhan, R; Shafiullah, M, 2010) |
"Vigabatrin (VGB) has several therapeutic advantages over older antiepileptic drugs (AED), but there is a lack of information about its potential reproductive toxicologic effects." | 1.36 | Vigabatrin (VGB) administered during late gestation lowers maternal folate concentration and causes pregnancy loss, fetal growth restriction and skeletal hypoplasia in the mouse. ( Abdulrazzaq, YM; Bastaki, SM; Nurulain, M; Padmanabhan, R; Shafiullah, M, 2010) |
"Vigabatrin (VGB) is a relatively recently introduced antiepileptic drug that enhances the brain levels of gamma aminobutyric acid (GABA)." | 1.30 | Teratogenic effects of vigabatrin in TO mouse fetuses. ( Abdulrazzaq, YM; Bastaki, SM; Padmanabhan, R, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Padmanabhan, R | 3 |
Abdulrazzaq, YM | 3 |
Bastaki, SM | 3 |
Nurulain, M | 1 |
Shafiullah, M | 1 |
Shafiullah, MM | 1 |
3 other studies available for vigabatrin and Fetal Growth Restriction
Article | Year |
---|---|
Vigabatrin (VGB) administered during late gestation lowers maternal folate concentration and causes pregnancy loss, fetal growth restriction and skeletal hypoplasia in the mouse.
Topics: Animals; Anticonvulsants; Bone and Bones; Dietary Supplements; Embryonic Development; Female; Fetal | 2010 |
Intrauterine growth restriction and skeletal variations in mouse fetuses induced by vigabatrin administered at preimplantation stages of development.
Topics: Animals; Anticonvulsants; Bone and Bones; Embryonic Development; Female; Fetal Growth Retardation; L | 2008 |
Teratogenic effects of vigabatrin in TO mouse fetuses.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Bone and Bones; Embryo Loss; Fetal Growth Ret | 1997 |