vigabatrin has been researched along with Drug Withdrawal Symptoms in 12 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We enrolled 120 patients with alcohol use disorder who were randomly assigned to either treatment with vigabatrin (2g/day for 4 days) or placebo." | 3.30 | A Placebo-Controlled Randomized Trial of Vigabatrin in the Management of Acute Alcohol Withdrawal. ( Bonomo, Y; Collins, L; Lloyd-Jones, M; Norman, A; O'Neill, H; Ogden, E; Pastor, A; Williams, J, 2023) |
| " In the test of physical dependence-producing potential with the drug-admixed food method in rats, vigabatrin and diazepam were given to rats mixed with food for 28 days in an increasing dosage schedule, followed by feeding a drug-free diet to observe withdrawal signs for 7 days." | 1.30 | Drug dependence study on vigabatrin in rhesus monkeys and rats. ( Takada, K; Yanagita, T, 1997) |
| "Vigabatrin proved to be a potent anticonvulsant drug at acute doses (100-200 mg/kg), but during chronic administration, the anticonvulsant activity of the treatment was lost already in the second week of treatment." | 1.28 | Development of tolerance to the anticonvulsant effect of vigabatrin in amygdala-kindled rats. ( Löscher, W; Rundfeldt, C, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 8 (66.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Williams, J | 1 |
| Collins, L | 1 |
| Norman, A | 1 |
| O'Neill, H | 1 |
| Lloyd-Jones, M | 1 |
| Ogden, E | 1 |
| Bonomo, Y | 1 |
| Pastor, A | 1 |
| Kröll-Seger, J | 1 |
| Kaminska, A | 1 |
| Moutard, ML | 1 |
| de Saint-Martin, A | 1 |
| Guët, A | 1 |
| Dulac, O | 2 |
| Chiron, C | 2 |
| Jawad, S | 1 |
| Clarke, E | 1 |
| Richens, A | 1 |
| Gram, L | 1 |
| Takada, K | 1 |
| Yanagita, T | 1 |
| Sayin, U | 1 |
| Atasoy, S | 1 |
| Uzbay, IT | 1 |
| Aricioğlu-Kartal, F | 1 |
| Koyuncuoğlu, H | 1 |
| Myrick, H | 1 |
| Brady, KT | 1 |
| Malcolm, R | 1 |
| Rundfeldt, C | 1 |
| Löscher, W | 1 |
| Staples, CI | 1 |
| King, MA | 1 |
| Boyle, RS | 1 |
| Ring, HA | 1 |
| Reynolds, EH | 1 |
| Brodie, MJ | 1 |
| McKee, PJ | 1 |
| Stahl, SM | 1 |
| Thornton, JE | 1 |
| Simpson, ML | 1 |
| Berger, PA | 1 |
| Napoliello, MJ | 1 |
1 review available for vigabatrin and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
New developments in the pharmacotherapy of alcohol dependence.
Topics: Acamprosate; Adjuvants, Anesthesia; Alcohol Deterrents; Alcoholism; Anticonvulsants; Buspirone; Carb | 2001 |
3 trials available for vigabatrin and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
A Placebo-Controlled Randomized Trial of Vigabatrin in the Management of Acute Alcohol Withdrawal.
Topics: Alcoholism; Benzodiazepines; Diazepam; Double-Blind Method; Humans; Substance Withdrawal Syndrome; V | 2023 |
Vigabatrin withdrawal randomized study in children.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Epilepsies, Partial; Epil | 1996 |
Vigabatrin and psychosis.
Topics: Adult; Aminocaproates; Anticonvulsants; Double-Blind Method; Drug Administration Schedule; Drug Eval | 1990 |
8 other studies available for vigabatrin and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Severe relapse of epilepsy after vigabatrin withdrawal: for how long should we treat symptomatic infantile spasms?
Topics: Cerebral Cortex; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; H | 2007 |
Vigabatrin-induced psychosis--management problems.
Topics: Adult; Brain Damage, Chronic; Carbamazepine; Female; gamma-Aminobutyric Acid; Humans; Psychoses, Sub | 1994 |
Drug dependence study on vigabatrin in rhesus monkeys and rats.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Barbital; Conditioning, Operant; Female; gamma-Aminobu | 1997 |
Gamma-vinyl-GABA potentiates the severity of naloxone-precipitated abstinence signs in morphine-dependent rats.
Topics: Animals; Anticonvulsants; Drug Synergism; gamma-Aminobutyric Acid; Male; Morphine Dependence; Naloxo | 1998 |
Development of tolerance to the anticonvulsant effect of vigabatrin in amygdala-kindled rats.
Topics: Amino Acids; Aminocaproates; Amygdala; Animals; Anticonvulsants; Disease Models, Animal; Drug Admini | 1992 |
Acute psychosis after withdrawal of vigabatrin.
Topics: Acute Disease; Adult; Aminocaproates; Anticonvulsants; Female; Humans; Psychoses, Substance-Induced; | 1992 |
Vigabatrin and behaviour disturbance.
Topics: Adult; Aminocaproates; Anticonvulsants; Humans; Male; Psychoses, Substance-Induced; Substance Withdr | 1990 |
Gamma-vinyl-GABA treatment of tardive dyskinesia and other movement disorders.
Topics: Adult; Aged; Aminocaproates; Confusion; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; H | 1985 |