vigabatrin has been researched along with Diathesis in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vigabatrin (VGB) is a new antiepileptic drug useful in refractOry partial seizures." | 2.41 | [Acute encephalopathy and myoclonic status induced by vigabatrin monotherapy] . ( García Pastor, A; García-Zarza, E; Peraita Adrados, R, 2000) |
| "Relapse was relatively common among all subgroups." | 1.51 | Very-High-Dose Prednisolone Before ACTH for Treatment of Infantile Spasms: Evaluation of a Standardized Protocol. ( Alayari, A; Eliyan, Y; Heesch, J; Hussain, SA; Rajaraman, RR; Sankar, R, 2019) |
| "Thus, the seizure-facilitating nigral efferents may be subject to inhibition by both GABA and opiates and may normally be driven by substance P." | 1.27 | Role of the substantia nigra in GABA-mediated anticonvulsant actions. ( Gale, K, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eliyan, Y | 1 |
| Heesch, J | 1 |
| Alayari, A | 1 |
| Rajaraman, RR | 1 |
| Sankar, R | 1 |
| Hussain, SA | 1 |
| Ibrahim, S | 1 |
| Gulab, S | 1 |
| Ishaque, S | 1 |
| Saleem, T | 1 |
| García Pastor, A | 1 |
| García-Zarza, E | 1 |
| Peraita Adrados, R | 1 |
| Vanhatalo, S | 1 |
| Nousiainen, I | 1 |
| Eriksson, K | 1 |
| Rantala, H | 1 |
| Vainionpää, L | 1 |
| Mustonen, K | 1 |
| Aärimaa, T | 1 |
| Alen, R | 1 |
| Aine, MR | 1 |
| Byring, R | 1 |
| Hirvasniemi, A | 1 |
| Nuutila, A | 1 |
| Walden, T | 1 |
| Ritanen-Mohammed, UM | 1 |
| Karttunen-Lewandowski, P | 1 |
| Pohjola, LM | 1 |
| Kaksonen, S | 1 |
| Jurvelin, P | 1 |
| Granström, ML | 1 |
| Gale, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prednisolone vs. Vigabatrin in the First-line Treatment of Infantile Spasms[NCT02299115] | Phase 3 | 0 participants (Actual) | Interventional | 2017-09-05 | Withdrawn (stopped due to Most centres are now using oral steroids as 1st line treatment so question of efficacy is no longer of high interest.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for vigabatrin and Diathesis
| Article | Year |
|---|---|
[Acute encephalopathy and myoclonic status induced by vigabatrin monotherapy] .
Topics: Acute Disease; Aged; Anticonvulsants; Brain Diseases, Metabolic; Cerebral Infarction; Disease Suscep | 2000 |
1 trial available for vigabatrin and Diathesis
| Article | Year |
|---|---|
Clinical profile and treatment of infantile spasms using vigabatrin and ACTH--a developing country perspective.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Asphyxia Neonatorum; Cerebral Palsy; Developing Countr | 2010 |
3 other studies available for vigabatrin and Diathesis
| Article | Year |
|---|---|
Very-High-Dose Prednisolone Before ACTH for Treatment of Infantile Spasms: Evaluation of a Standardized Protocol.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Clinical Protocols; Cohort Studies; Disease Susceptibi | 2019 |
Visual field constriction in 91 Finnish children treated with vigabatrin.
Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Disease Susceptibility; Dose-Resp | 2002 |
Role of the substantia nigra in GABA-mediated anticonvulsant actions.
Topics: Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Brain Diseases; Denervation; D | 1986 |