vigabatrin has been researched along with Developmental Psychomotor Disorders in 4 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a patient with early infantile epileptic encephalopathy with suppression bursts (Ohtahara syndrome) with an excellent response to chloral hydrate to draw attention to a possible role of the "old" drug in the treatment of intractable epilepsy." | 7.71 | Successful treatment of Ohtahara syndrome with chloral hydrate. ( Komárek, V; Krsek, P; Maulisová, A; Procházka, T; Sebronová, V, 2002) |
| "We present a patient with early infantile epileptic encephalopathy with suppression bursts (Ohtahara syndrome) with an excellent response to chloral hydrate to draw attention to a possible role of the "old" drug in the treatment of intractable epilepsy." | 3.71 | Successful treatment of Ohtahara syndrome with chloral hydrate. ( Komárek, V; Krsek, P; Maulisová, A; Procházka, T; Sebronová, V, 2002) |
| "Vigabatrin (VGB) was specifically synthesized to enhance inhibitory GABAergic transmission by elevating GABA levels via irreversible inhibition of GABA transaminase." | 1.30 | [Monotherapy with vigabatrin in the treatment of West's syndrome]. ( Castro, E; Ocaña, O; Rufo, M; Santiago, C, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Djuric, M | 1 |
| Kravljanac, R | 1 |
| Tadic, B | 1 |
| Mrlješ-Popovic, N | 1 |
| Appleton, RE | 1 |
| Krsek, P | 1 |
| Sebronová, V | 1 |
| Procházka, T | 1 |
| Maulisová, A | 1 |
| Komárek, V | 1 |
| Levav, T | 1 |
| Saar, T | 1 |
| Berkovich, L | 1 |
| Golan, H | 1 |
| Rufo, M | 1 |
| Santiago, C | 1 |
| Castro, E | 1 |
| Ocaña, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacotoxicology of Trichloroethylene Metabolites: Short-term Effect of DCA on in Vivo Tyrosine Catabolism and MAAI Expression[NCT00865514] | 2 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Difficulty in obtaining the solution from the compounding pharmacies caused a two year delay in start-up; the funding ended prior to study completion.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for vigabatrin and Developmental Psychomotor Disorders
| Article | Year |
|---|---|
Long-term outcome in children with infantile spasms treated with vigabatrin: a cohort of 180 patients.
Topics: Adolescent; Anticonvulsants; Chi-Square Distribution; Child; Child, Preschool; Cohort Studies; Femal | 2014 |
Successful treatment of Ohtahara syndrome with chloral hydrate.
Topics: Anticonvulsants; Chloral Hydrate; Drug Therapy, Combination; Electroencephalography; Female; Humans; | 2002 |
Perinatal exposure to GABA-transaminase inhibitor impaired psychomotor function in the developing and adult mouse.
Topics: 4-Aminobutyrate Transaminase; Animals; Animals, Newborn; Anticonvulsants; Hippocampus; Mice; Mice, I | 2004 |
[Monotherapy with vigabatrin in the treatment of West's syndrome].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Female; gamma-Aminobutyric Acid; Humans; Infant; Male; | 1997 |