Page last updated: 2024-11-05

vigabatrin and Developmental Disabilities

vigabatrin has been researched along with Developmental Disabilities in 15 studies

Developmental Disabilities: Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)

Research Excerpts

ExcerptRelevanceReference
"Early EEG findings help to identify TSC infants at risk of severe epilepsy and neurodevelopmental delay and those who may benefit from preventive treatment with vigabatrin."5.41Early epileptiform EEG activity in infants with tuberous sclerosis complex predicts epilepsy and neurodevelopmental outcomes. ( Aronica, E; Benova, B; Curatolo, P; De Ridder, J; Domanska-Pakieła, D; Ferrier, CH; Feucht, M; Hertzberg, C; Jansen, AC; Jansen, FE; Jóźwiak, S; Kaczorowska-Frontczak, M; Kotulska, K; Krsek, P; Kwiatkowski, DJ; Lagae, L; Lemmens, K; Moavero, R; Nabbout, R; Riney, K; Samueli, S; Verhelle, B; Vervisch, J; Weschke, B; Wojdan, K, 2021)
" We retrospectively evaluated the long-term outcome of 44 infants presenting with seizures in the first 12 months who received vigabatrin, and were followed up for at least 3."3.77Long-term neurological outcome in children with early-onset epilepsy associated with tuberous sclerosis. ( Bombardieri, R; Curatolo, P; Cusmai, R; Moavero, R; Vigevano, F, 2011)
" The child was treated with vigabatrin at age 6 months after an abnormal electroencephalogram but before onset of seizures."3.73Autistic regression associated with seizure onset in an infant with tuberous sclerosis. ( Bolton, PF; Clarke, A; Humphrey, A; Neville, BG, 2006)
"Early treatment of infantile spasms seems to be important."2.46Favourable prognostic factors with infantile spasms. ( Riikonen, RS, 2010)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (33.33)18.2507
2000's3 (20.00)29.6817
2010's5 (33.33)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Moavero, R3
Kotulska, K2
Lagae, L3
Benvenuto, A1
Emberti Gialloreti, L1
Weschke, B2
Riney, K2
Feucht, M2
Krsek, P2
Nabbout, R2
Jansen, AC2
Wojdan, K2
Borkowska, J1
Sadowski, K1
Hertzberg, C2
Van Schooneveld, MM1
Samueli, S2
Maulisovà, A1
Aronica, E2
Kwiatkowski, DJ2
Jansen, FE2
Jozwiak, S2
Curatolo, P3
De Ridder, J1
Verhelle, B1
Vervisch, J1
Lemmens, K1
Domanska-Pakieła, D1
Kaczorowska-Frontczak, M1
Ferrier, CH1
Benova, B1
Horvath, GA1
Hukin, J1
Stockler-Ipsiroglu, SG1
Aroichane, M1
Sun, LR1
Bosemani, T1
Smith-Hicks, CL1
Karvelas, G1
Lortie, A1
Scantlebury, MH1
Duy, PT1
Cossette, P1
Carmant, L1
Riikonen, RS1
Verhelst, H1
Ceulemans, B1
De Meirleir, L1
Nassogne, MC1
De Borchgrave, V1
D'Hooghe, M1
Foulon, M1
Van Bogaert, P1
Cusmai, R1
Bombardieri, R1
Vigevano, F1
Ergezinger, K1
Jeschke, R1
Frauendienst-Egger, G1
Korall, H1
Gibson, KM3
Schuster, VH1
Humphrey, A1
Neville, BG1
Clarke, A1
Bolton, PF1
Kok, RM1
Howells, DW1
van den Heuvel, CC1
Guérand, WS1
Thompson, GN1
Jakobs, C3
Christensen, E1
Fowler, B1
Clarke, MA1
Hammersen, G1
Raab, K1
Kobori, J1
Moosa, A1
Vollmer, B1
Rossier, E1
Iafolla, AK1
Matern, D1
Brouwer, OF1
Finkelstein, J1
Aksu, F1
Weber, HP1
Bakkeren, JA1
Gabreels, FJ1
Bluestone, D1
Barron, TF1
Beauvais, P1
Rabier, D1
Santos, C1
Lehnert, W1
Hoffmann, GF1
Hodson, AK1
Bottiglieri, T1
Dooley, J1
Gordon, K1
Dooley, K1
Wohlrab, G1
Boltshauser, E1
Schmitt, B1

Reviews

2 reviews available for vigabatrin and Developmental Disabilities

ArticleYear
Favourable prognostic factors with infantile spasms.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2010, Volume: 14, Issue:1

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Developmental Disabilities; Electroencephalography; Hu

2010
4-Hydroxybutyric acid and the clinical phenotype of succinic semialdehyde dehydrogenase deficiency, an inborn error of GABA metabolism.
    Neuropediatrics, 1998, Volume: 29, Issue:1

    Topics: Aldehyde Oxidoreductases; Animals; Anticonvulsants; Child; Developmental Disabilities; Disease Model

1998

Trials

3 trials available for vigabatrin and Developmental Disabilities

ArticleYear
Is autism driven by epilepsy in infants with Tuberous Sclerosis Complex?
    Annals of clinical and translational neurology, 2020, Volume: 7, Issue:8

    Topics: Anticonvulsants; Autism Spectrum Disorder; Child, Preschool; Developmental Disabilities; Epilepsy; F

2020
Early epileptiform EEG activity in infants with tuberous sclerosis complex predicts epilepsy and neurodevelopmental outcomes.
    Epilepsia, 2021, Volume: 62, Issue:5

    Topics: Anticonvulsants; Developmental Disabilities; Early Diagnosis; Electroencephalography; Epilepsy; Fema

2021
Vigabatrin as a first-line drug in West syndrome: clinical and electroencephalographic outcome.
    Neuropediatrics, 1998, Volume: 29, Issue:3

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Cerebral Cortex; Child, Preschool; Developmental Disab

1998

Other Studies

10 other studies available for vigabatrin and Developmental Disabilities

ArticleYear
Eye Findings on Vigabatrin and Taurine Treatment in Two Patients with Succinic Semialdehyde Dehydrogenase Deficiency.
    Neuropediatrics, 2016, Volume: 47, Issue:4

    Topics: Amino Acid Metabolism, Inborn Errors; Anticonvulsants; Child; Developmental Disabilities; Electroret

2016
Neuroimaging Abnormalities in a Child With Infantile Spasms on High-Dose Vigabatrin.
    Pediatric neurology, 2017, Volume: 67

    Topics: Developmental Disabilities; Down Syndrome; Dyskinesia, Drug-Induced; Female; GABA Agents; Humans; In

2017
A retrospective study on aetiology based outcome of infantile spasms.
    Seizure, 2009, Volume: 18, Issue:3

    Topics: Anticonvulsants; Cognition Disorders; Developmental Disabilities; Electroencephalography; Female; Fo

2009
Treatment and long term outcome in West syndrome: the clinical reality. A multicentre follow up study.
    Seizure, 2010, Volume: 19, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Developmental Disabilities; F

2010
Long-term neurological outcome in children with early-onset epilepsy associated with tuberous sclerosis.
    Epilepsy & behavior : E&B, 2011, Volume: 22, Issue:4

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cognition Disorders; Developmental Disabilitie

2011
Monitoring of 4-hydroxybutyric acid levels in body fluids during vigabatrin treatment in succinic semialdehyde dehydrogenase deficiency.
    Annals of neurology, 2003, Volume: 54, Issue:5

    Topics: Aldehyde Oxidoreductases; Child; Developmental Disabilities; Enzyme Inhibitors; Female; Humans; Hydr

2003
Autistic regression associated with seizure onset in an infant with tuberous sclerosis.
    Developmental medicine and child neurology, 2006, Volume: 48, Issue:7

    Topics: Anticonvulsants; Autistic Disorder; Developmental Disabilities; Epilepsy; Humans; Infant; Male; Regr

2006
Stable isotope dilution analysis of GABA in CSF using simple solvent extraction and electron-capture negative-ion mass fragmentography.
    Journal of inherited metabolic disease, 1993, Volume: 16, Issue:3

    Topics: Aldehyde Oxidoreductases; Anticonvulsants; Carbohydrate Metabolism, Inborn Errors; Child; Developmen

1993
The clinical phenotype of succinic semialdehyde dehydrogenase deficiency (4-hydroxybutyric aciduria): case reports of 23 new patients.
    Pediatrics, 1997, Volume: 99, Issue:4

    Topics: Adolescent; Adult; Aldehyde Oxidoreductases; Child; Child, Preschool; Developmental Disabilities; Di

1997
Falsely elevated urinary ethanolamine levels due to vigabatrin.
    Journal of child neurology, 1998, Volume: 13, Issue:6

    Topics: Anticonvulsants; Child, Preschool; Developmental Disabilities; Ethanolamine; Female; gamma-Aminobuty

1998