vigabatrin has been researched along with Convulsions, Grand Mal in 11 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-five patients with epilepsy (mostly with partial seizures) who had responded favourably to a short-term trial of add-on vigabatrin entered maintenance treatment." | 7.68 | Six-year follow-up study on the efficacy and safety of vigabatrin in patients with epilepsy. ( Galimberti, CA; Iudice, A; Manni, R; Morini, R; Mumford, JP; Perucca, E; Tartara, A, 1992) |
| "Vigabatrin is a specific and irreversible inhibitor of the enzyme gamma-amino-butyric-acid (GABA) transferase." | 6.39 | [Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic]. ( Krämer, G; Vogt, H, 1995) |
| "Clonic seizures were rare in NMDA-treated P25 rats, but valproate pretreatment increased their incidence significantly." | 5.36 | Vigabatrin but not valproate prevents development of age-specific flexion seizures induced by N-methyl-D-aspartate (NMDA) in immature rats. ( Kubová, H; Mares, P, 2010) |
| "The incidence of minimal, predominantly clonic seizures was not changed in any age group, but their latencies were prolonged in 18- and 25-day-old rats." | 5.31 | Does vigabatrin possess an anticonvulsant action against pentylenetetrazol-induced seizures in developing rats? ( Haugvicová, R; Kubová, H; Mares, P, 2002) |
| "The effect of introducing vigabatrin into the management of 57 patients with severe epilepsy is reported." | 3.68 | Vigabatrin: a three year clinical analysis. ( Martin, PJ; Millac, PA, 1993) |
| "Twenty-five patients with epilepsy (mostly with partial seizures) who had responded favourably to a short-term trial of add-on vigabatrin entered maintenance treatment." | 3.68 | Six-year follow-up study on the efficacy and safety of vigabatrin in patients with epilepsy. ( Galimberti, CA; Iudice, A; Manni, R; Morini, R; Mumford, JP; Perucca, E; Tartara, A, 1992) |
| "Vigabatrin is a specific and irreversible inhibitor of the enzyme gamma-amino-butyric-acid (GABA) transferase." | 2.39 | [Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic]. ( Krämer, G; Vogt, H, 1995) |
| "Clonic seizures were rare in NMDA-treated P25 rats, but valproate pretreatment increased their incidence significantly." | 1.36 | Vigabatrin but not valproate prevents development of age-specific flexion seizures induced by N-methyl-D-aspartate (NMDA) in immature rats. ( Kubová, H; Mares, P, 2010) |
| "Vigabatrin is an antiepileptic drug and may increase the intraretinal GABA level due to an inhibition of the enzyme GABA-transaminase and may induce an ascending simple optic nerve atrophy." | 1.32 | [Vigabatrin-associated bilateral simple optic nerve atrophy with visual field constriction. A case report and a survey of the literature]. ( Mardin, CY; Viestenz, A, 2003) |
| "The incidence of minimal, predominantly clonic seizures was not changed in any age group, but their latencies were prolonged in 18- and 25-day-old rats." | 1.31 | Does vigabatrin possess an anticonvulsant action against pentylenetetrazol-induced seizures in developing rats? ( Haugvicová, R; Kubová, H; Mares, P, 2002) |
| "A patient with focal epilepsy that was resistant to medical treatment received add-on therapy with vigabatrin." | 1.29 | [Allergic vasculitis caused by Vigabatrin]. ( Becker, EW; Berg, PA; Berkenfeld, R; Dieterle, L; Reinshagen, G, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kubová, H | 2 |
| Mares, P | 2 |
| Haugvicová, R | 1 |
| Viestenz, A | 2 |
| Mardin, CY | 1 |
| Marciani, MG | 1 |
| Maschio, M | 1 |
| Spanedda, F | 1 |
| Iani, C | 1 |
| Gigli, GL | 1 |
| Bernardi, G | 1 |
| Vogt, H | 1 |
| Krämer, G | 1 |
| Sälke-Kellermann, A | 1 |
| Baier, H | 1 |
| Rambeck, B | 1 |
| Boenigk, HE | 1 |
| Wolf, P | 1 |
| Dieterle, L | 1 |
| Becker, EW | 1 |
| Berg, PA | 1 |
| Berkenfeld, R | 1 |
| Reinshagen, G | 1 |
| Martin, PJ | 1 |
| Millac, PA | 1 |
| Schapel, G | 1 |
| Chadwick, D | 1 |
| Cocito, L | 1 |
| Primavera, A | 1 |
| Tartara, A | 1 |
| Manni, R | 1 |
| Galimberti, CA | 1 |
| Morini, R | 1 |
| Mumford, JP | 1 |
| Iudice, A | 1 |
| Perucca, E | 1 |
1 review available for vigabatrin and Convulsions, Grand Mal
| Article | Year |
|---|---|
[Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic].
Topics: 4-Aminobutyrate Transaminase; Adult; Anticonvulsants; Child; Drug Therapy, Combination; Epilepsies, | 1995 |
10 other studies available for vigabatrin and Convulsions, Grand Mal
| Article | Year |
|---|---|
Vigabatrin but not valproate prevents development of age-specific flexion seizures induced by N-methyl-D-aspartate (NMDA) in immature rats.
Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Disease Models, Animal; E | 2010 |
Does vigabatrin possess an anticonvulsant action against pentylenetetrazol-induced seizures in developing rats?
Topics: Animals; Animals, Newborn; Anticonvulsants; Convulsants; Epilepsy, Generalized; Epilepsy, Tonic-Clon | 2002 |
[Vigabatrin-associated bilateral simple optic nerve atrophy with visual field constriction. A case report and a survey of the literature].
Topics: Aged; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Evoked Potentials, | 2003 |
Development of myoclonus in patients with partial epilepsy during treatment with vigabatrin: an electroencephalographic study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain; Carbamazepine; Delta Rhythm; Electroencephalography | 1995 |
Acute encephalopathy with vigabatrin.
Topics: 4-Aminobutyrate Transaminase; Adolescent; Adult; Aminocaproates; Anticonvulsants; Carbamazepine; Com | 1993 |
[Allergic vasculitis caused by Vigabatrin].
Topics: Adult; Aminocaproates; Anticonvulsants; Dose-Response Relationship, Drug; Drug Administration Schedu | 1994 |
Vigabatrin: a three year clinical analysis.
Topics: Adolescent; Adult; Aminocaproates; Anticonvulsants; Cerebral Cortex; Dose-Response Relationship, Dru | 1993 |
A survey comparing lamotrigine and vigabatrin in everyday clinical practice.
Topics: Anticonvulsants; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epile | 1996 |
Vigabatrin aggravates absences and absence status.
Topics: Adult; Anticonvulsants; Asphyxia; Brain Damage, Chronic; Carbamazepine; Drug Therapy, Combination; E | 1998 |
Six-year follow-up study on the efficacy and safety of vigabatrin in patients with epilepsy.
Topics: Adolescent; Adult; Aminocaproates; Anticonvulsants; Brain Stem; Cerebral Cortex; Electroencephalogra | 1992 |