vigabatrin has been researched along with Complications, Pregnancy in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vigabatrin was specifically designed to enhance gamma-aminobutyric acid (GABA) function in the CNS." | 7.77 | Vigabatrin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control. ( Grant, SM; Heel, RC, 1991) |
| "Vigabatrin was specifically designed to enhance gamma-aminobutyric acid (GABA) function in the CNS." | 3.77 | Vigabatrin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control. ( Grant, SM; Heel, RC, 1991) |
| " By contrast, offspring of rats exposed to carbamazepine (which at the dose used produced low plasma concentrations) or to generalized convulsive seizures showed no clear-cut evidence of dysplasias." | 3.74 | Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias. ( Ben-Ari, Y; Depaulis, A; Jorquera, I; Manent, JB; Mazzucchelli, I; Perucca, E; Represa, A, 2007) |
| " In the last decade, pregnancy registries have been activated by collaborative groups of physicians in Europe (EURAP), North America (NAREP), Australia and India (the latter two recently merged into EURAP), to enroll a large number of exposed women to be monitored prospectively with standardized methods, and by three pharmaceutical companies marketing lamotrigine, gabapentin and vigabatrin, as part of their post-marketing surveillance." | 3.71 | Pregnancy registries in epilepsy. ( Annegers, JF; Beghi, E, 2001) |
| "5 months of pregnancy then carbamazepine 400 mg LP x 2/day, raised to 600 mg LP x 2/day at the 25th week of gestation because of epileptic crisis." | 3.69 | [Carbamazepine and vigabatrin in epileptic pregnant woman and side effects in the newborn infant]. ( Aboulghit, H; Beust, M; Kayemba Kay'S, S; Mourtada, A; Voisin, M, 1997) |
| "Vigabatrin is a new antiepileptic medication consisting of a racemic mixture of 50% active S enantiomer and 50% inactive R enantiomer." | 1.30 | Vigabatrin: placental transfer in vivo and excretion into breast milk of the enantiomers. ( Mai, J; Mumford, JP; O'Mahoney, T; Olive, G; Rey, E; Tran, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lawthom, C | 1 |
| Smith, PE | 1 |
| Wild, JM | 1 |
| Gosakan, R | 1 |
| von Knorring, N | 1 |
| Stewart, P | 1 |
| Wu, SP | 1 |
| Shyu, MK | 1 |
| Liou, HH | 1 |
| Gau, CS | 1 |
| Lin, CJ | 1 |
| Manent, JB | 1 |
| Jorquera, I | 1 |
| Mazzucchelli, I | 1 |
| Depaulis, A | 1 |
| Perucca, E | 1 |
| Ben-Ari, Y | 1 |
| Represa, A | 1 |
| Kayemba Kay'S, S | 1 |
| Beust, M | 1 |
| Aboulghit, H | 1 |
| Voisin, M | 1 |
| Mourtada, A | 1 |
| Tran, A | 1 |
| O'Mahoney, T | 1 |
| Rey, E | 1 |
| Mai, J | 1 |
| Mumford, JP | 1 |
| Olive, G | 1 |
| Beghi, E | 1 |
| Annegers, JF | 1 |
| Grant, SM | 1 |
| Heel, RC | 1 |
1 review available for vigabatrin and Complications, Pregnancy
| Article | Year |
|---|---|
Vigabatrin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control.
Topics: 4-Aminobutyrate Transaminase; Adult; Aged; Aminocaproates; Animals; Ataxia; Child; Dyskinesia, Drug- | 1991 |
1 trial available for vigabatrin and Complications, Pregnancy
| Article | Year |
|---|---|
Vigabatrin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control.
Topics: 4-Aminobutyrate Transaminase; Adult; Aged; Aminocaproates; Animals; Ataxia; Child; Dyskinesia, Drug- | 1991 |
7 other studies available for vigabatrin and Complications, Pregnancy
| Article | Year |
|---|---|
In utero exposure to vigabatrin: no indication of visual field loss.
Topics: Adolescent; Adult; Anticonvulsants; Child; Dose-Response Relationship, Drug; Epilepsies, Partial; Fe | 2009 |
Successful pregnancy in a patient with hyperoxaluria and combined liver and renal transplant.
Topics: Adult; Epilepsy; Female; Humans; Hyperoxaluria; Infant, Newborn; Kidney Transplantation; Liver Trans | 2003 |
Interaction between anticonvulsants and human placental carnitine transporter.
Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techn | 2004 |
Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Female; Fetus | 2007 |
[Carbamazepine and vigabatrin in epileptic pregnant woman and side effects in the newborn infant].
Topics: Alkaline Phosphatase; Anticonvulsants; Carbamazepine; Chlorine; Drug Therapy, Combination; Epilepsy; | 1997 |
Vigabatrin: placental transfer in vivo and excretion into breast milk of the enantiomers.
Topics: Adult; Anticonvulsants; Central Nervous System; Female; Fetal Blood; gamma-Aminobutyric Acid; Humans | 1998 |
Pregnancy registries in epilepsy.
Topics: Abnormalities, Drug-Induced; Acetates; Amines; Anticonvulsants; Australia; Cross-Cultural Comparison | 2001 |