vigabatrin has been researched along with Cognition Disorders in 14 studies
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To review the efficacy, cognitive outcome and safety profile in children treated with vigabatrin (VGB) for infantile spasms (IS) and partial epilepsies related to tuberous sclerosis complex (TSC) and other etiologies." | 7.74 | Vigabatrin in the treatment of childhood epilepsy: a retrospective chart review of efficacy and safety profile. ( Camposano, SE; Halpern, E; Major, P; Thiele, EA, 2008) |
| "Vigabatrin (VGB) has demonstrated high efficacy in infantile spasms (IS) due to tuberous sclerosis." | 7.70 | Mental and behavioural outcome of infantile epilepsy treated by vigabatrin in tuberous sclerosis patients. ( Chiron, C; Dulac, O; Dumas, C; Jambaqué, I; Mumford, J, 2000) |
| "The objective of this study was to compare the efficacy of corticotropin (ACTH) versus vigabatrin in treating infantile spasms and to determine which medication has a more favorable long-term outcome in terms of cognitive function, evolution of epilepsy, and incidence of autism." | 5.10 | Prospective preliminary analysis of the development of autism and epilepsy in children with infantile spasms. ( Askalan, R; Boyd, J; Brian, J; Bryson, S; Mackay, M; McDermott, C; Otsubo, H; Roberts, W; Snead, C; Weiss, S, 2003) |
| " We retrospectively evaluated the long-term outcome of 44 infants presenting with seizures in the first 12 months who received vigabatrin, and were followed up for at least 3." | 3.77 | Long-term neurological outcome in children with early-onset epilepsy associated with tuberous sclerosis. ( Bombardieri, R; Curatolo, P; Cusmai, R; Moavero, R; Vigevano, F, 2011) |
| "To review the efficacy, cognitive outcome and safety profile in children treated with vigabatrin (VGB) for infantile spasms (IS) and partial epilepsies related to tuberous sclerosis complex (TSC) and other etiologies." | 3.74 | Vigabatrin in the treatment of childhood epilepsy: a retrospective chart review of efficacy and safety profile. ( Camposano, SE; Halpern, E; Major, P; Thiele, EA, 2008) |
| "Vigabatrin (VGB) has demonstrated high efficacy in infantile spasms (IS) due to tuberous sclerosis." | 3.70 | Mental and behavioural outcome of infantile epilepsy treated by vigabatrin in tuberous sclerosis patients. ( Chiron, C; Dulac, O; Dumas, C; Jambaqué, I; Mumford, J, 2000) |
| "Vigabatrin is an effective antiepileptic drug (AED) for the treatment of refractory complex partial seizures (rCPS) and infantile spasms (IS)." | 2.47 | Non-vision adverse events with vigabatrin therapy. ( Kälviäinen, R; Walker, SD, 2011) |
| "Vigabatrin has been shown to be particularly effective in treating infantile spasms in the setting of tuberous sclerosis complex." | 2.42 | Managing epilepsy in tuberous sclerosis complex. ( Thiele, EA, 2004) |
| "Early control of seizures has a crucial role in preventing subsequent epileptic encephalopathy, and in reducing the cognitive/behavioural consequences of seizures, but does not guarantee for a normal mental outcome in children with TSC." | 1.36 | Early control of seizures improves long-term outcome in children with tuberous sclerosis complex. ( Bombardieri, R; Cerminara, C; Curatolo, P; Moavero, R; Pinci, M, 2010) |
| "Infantile spasms are characterized by age-specific expression of epileptic spasms and hypsarrhythmia and often result in significant cognitive impairment." | 1.36 | A model of symptomatic infantile spasms syndrome. ( Betancourth, D; Chudomelova, L; Galanopoulou, AS; Moshé, SL; Raffo, E; Scantlebury, MH, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Riikonen, R | 1 |
| Karvelas, G | 1 |
| Lortie, A | 1 |
| Scantlebury, MH | 2 |
| Duy, PT | 1 |
| Cossette, P | 1 |
| Carmant, L | 1 |
| Bombardieri, R | 3 |
| Pinci, M | 1 |
| Moavero, R | 2 |
| Cerminara, C | 2 |
| Curatolo, P | 3 |
| Galanopoulou, AS | 1 |
| Chudomelova, L | 1 |
| Raffo, E | 1 |
| Betancourth, D | 1 |
| Moshé, SL | 1 |
| Cavanna, AE | 1 |
| Ali, F | 1 |
| Rickards, HE | 1 |
| McCorry, D | 1 |
| Walker, SD | 1 |
| Kälviäinen, R | 1 |
| Cusmai, R | 1 |
| Vigevano, F | 1 |
| Askalan, R | 1 |
| Mackay, M | 1 |
| Brian, J | 1 |
| Otsubo, H | 1 |
| McDermott, C | 1 |
| Bryson, S | 1 |
| Boyd, J | 1 |
| Snead, C | 1 |
| Roberts, W | 1 |
| Weiss, S | 1 |
| Thiele, EA | 2 |
| Camposano, SE | 1 |
| Major, P | 1 |
| Halpern, E | 1 |
| Jambaqué, I | 1 |
| Chiron, C | 1 |
| Dumas, C | 1 |
| Mumford, J | 1 |
| Dulac, O | 1 |
| Aldenkamp, AP | 1 |
| Calvet, D | 1 |
| Touzé, E | 1 |
| Delegue, P | 1 |
| Bertherat, J | 1 |
| Zuber, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prednisolone vs. Vigabatrin in the First-line Treatment of Infantile Spasms[NCT02299115] | Phase 3 | 0 participants (Actual) | Interventional | 2017-09-05 | Withdrawn (stopped due to Most centres are now using oral steroids as 1st line treatment so question of efficacy is no longer of high interest.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for vigabatrin and Cognition Disorders
| Article | Year |
|---|---|
Recent advances in the pharmacotherapy of infantile spasms.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Cognition Disorders; | 2014 |
Behavioral and cognitive effects of anti-epileptic drugs.
Topics: Amines; Anticonvulsants; Antidepressive Agents; Behavior; Cognition; Cognition Disorders; Cyclohexan | 2010 |
Non-vision adverse events with vigabatrin therapy.
Topics: 4-Aminobutyrate Transaminase; Adolescent; Adult; Animals; Anticonvulsants; Brain Diseases; Cognition | 2011 |
Managing epilepsy in tuberous sclerosis complex.
Topics: Anticonvulsants; Child; Cognition Disorders; Diet Therapy; Electroencephalography; Epilepsy; Humans; | 2004 |
Current management for epilepsy in tuberous sclerosis complex.
Topics: Animals; Anticonvulsants; Brain Injuries; Cognition Disorders; Epilepsy; Humans; Neurosurgery; Tuber | 2006 |
1 trial available for vigabatrin and Cognition Disorders
| Article | Year |
|---|---|
Prospective preliminary analysis of the development of autism and epilepsy in children with infantile spasms.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Autistic Disorder; Cognition Disorders; Electroencepha | 2003 |
8 other studies available for vigabatrin and Cognition Disorders
| Article | Year |
|---|---|
A retrospective study on aetiology based outcome of infantile spasms.
Topics: Anticonvulsants; Cognition Disorders; Developmental Disabilities; Electroencephalography; Female; Fo | 2009 |
Early control of seizures improves long-term outcome in children with tuberous sclerosis complex.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cognition Disorders; Electroencephalography; F | 2010 |
A model of symptomatic infantile spasms syndrome.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Antibiotics, Antineoplastic; Anticonvulsants | 2010 |
Long-term neurological outcome in children with early-onset epilepsy associated with tuberous sclerosis.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cognition Disorders; Developmental Disabilitie | 2011 |
Vigabatrin in the treatment of childhood epilepsy: a retrospective chart review of efficacy and safety profile.
Topics: Anticonvulsants; Child; Child, Preschool; Cognition Disorders; Electroretinography; Epilepsies, Part | 2008 |
Mental and behavioural outcome of infantile epilepsy treated by vigabatrin in tuberous sclerosis patients.
Topics: Anticonvulsants; Autistic Disorder; Child Behavior Disorders; Cognition Disorders; Drug Therapy, Com | 2000 |
Effects of antiepileptic drugs on cognition.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Cyclohexanecarboxy | 2001 |
[Stiff limb syndrome associated with Hashimoto's encephalopathy: improvement after corticotherapy].
Topics: Aged; Antibody Specificity; Anticonvulsants; Antithyroid Agents; Autoantibodies; Autoimmune Diseases | 2002 |