vigabatrin has been researched along with Chronic Disease in 9 studies
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the long-term retention of gabapentin (GBP), lamotrigine (LTG), and vigabatrin (VGB) by patients with chronic epilepsy and the reasons for treatment discontinuation." | 7.70 | The long-term use of gabapentin, lamotrigine, and vigabatrin in patients with chronic epilepsy. ( Chadwick, DW; Fenwick, PB; Mawer, GE; Sander, JW; Wong, IC, 1999) |
| "Vigabatrin is a selective, irreversible suicide inhibitor of GABA transaminase and thus increases brain and CSF GABA." | 6.67 | Vigabatrin: rational treatment for chronic epilepsy. ( Farr, IN; Heller, AJ; Reynolds, EH; Ring, HA, 1990) |
| "This report describes the long-term follow-up of 56 patients with refractory partial epilepsy who, within 3 months of vigabatrin add-on therapy (3 g/day), showed a reduction in monthly seizure frequency of more than 50%." | 3.70 | Long-term treatment with vigabatrin - 10 years of clinical experience. ( Mumford, JP; Riekkinen, PJ; Salmenperä, T; Ylinen, A, 1999) |
| "To compare the long-term retention of gabapentin (GBP), lamotrigine (LTG), and vigabatrin (VGB) by patients with chronic epilepsy and the reasons for treatment discontinuation." | 3.70 | The long-term use of gabapentin, lamotrigine, and vigabatrin in patients with chronic epilepsy. ( Chadwick, DW; Fenwick, PB; Mawer, GE; Sander, JW; Wong, IC, 1999) |
| "Since anticonvulsants have been used for treating neuralgias, an interest has arisen to experimentally test vigabatrin for its gabaergic mechanism of action." | 3.70 | Possible analgesic effect of vigabatrin in animal experimental chronic neuropathic pain. ( Alves, ND; de Carvalho, AM; de Castro-Costa, CM; Santos, FJ; Silveira, DG, 1999) |
| "Vigabatrin was administered as "add on therapy" (Table 1) and monotherapy (Table 2)." | 2.67 | [Gamma-vinyl-GABA: the first trials in Italy]. ( de Romanis, F; Sopranzi, N, 1993) |
| "Vigabatrin is a selective, irreversible suicide inhibitor of GABA transaminase and thus increases brain and CSF GABA." | 2.67 | Vigabatrin: rational treatment for chronic epilepsy. ( Farr, IN; Heller, AJ; Reynolds, EH; Ring, HA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (88.89) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thelle, T | 1 |
| Gammelgaard, L | 1 |
| Hansen, JK | 1 |
| Østergaard, JR | 1 |
| de Romanis, F | 1 |
| Sopranzi, N | 1 |
| Walker, MC | 1 |
| Li, LM | 1 |
| Sander, JW | 2 |
| Wilson, EA | 1 |
| Brodie, MJ | 1 |
| Ylinen, A | 1 |
| Salmenperä, T | 1 |
| Mumford, JP | 1 |
| Riekkinen, PJ | 1 |
| Wong, IC | 1 |
| Chadwick, DW | 1 |
| Fenwick, PB | 1 |
| Mawer, GE | 1 |
| Alves, ND | 1 |
| de Castro-Costa, CM | 1 |
| de Carvalho, AM | 1 |
| Santos, FJ | 1 |
| Silveira, DG | 1 |
| Reynolds, EH | 2 |
| Ring, HA | 1 |
| Heller, AJ | 1 |
| Farr, IN | 1 |
1 review available for vigabatrin and Chronic Disease
| Article | Year |
|---|---|
Gamma-vinyl GABA (vigabatrin): clinical experience in adult and adolescent patients with intractable epilepsy.
Topics: Adolescent; Adult; Age Factors; Aminocaproates; Anticonvulsants; Chronic Disease; Epilepsies, Partia | 1992 |
2 trials available for vigabatrin and Chronic Disease
| Article | Year |
|---|---|
[Gamma-vinyl-GABA: the first trials in Italy].
Topics: Adolescent; Adult; Aminocaproates; Anticonvulsants; Chronic Disease; Drug Therapy, Combination; Epil | 1993 |
Vigabatrin: rational treatment for chronic epilepsy.
Topics: Adolescent; Adult; Aminocaproates; Anticonvulsants; Chronic Disease; Double-Blind Method; Drug Admin | 1990 |
6 other studies available for vigabatrin and Chronic Disease
| Article | Year |
|---|---|
Reversible magnetic resonance imaging and spectroscopy abnormalities in the course of vigabatrin treatment for West syndrome.
Topics: Anticonvulsants; Basal Ganglia Diseases; Brain Diseases, Metabolic; Chronic Disease; Humans; Infant; | 2011 |
Long-term use of lamotrigine and vigabatrin in severe refractory epilepsy: audit of outcome.
Topics: Chronic Disease; Clinical Trials as Topic; Epilepsy; Follow-Up Studies; gamma-Aminobutyric Acid; Hum | 1996 |
Severe persistent visual field constriction associated with vigabatrin. Chronic refractory epilepsy may have role in causing these unusual lesions.
Topics: Adult; Anticonvulsants; Chronic Disease; Epilepsy; gamma-Aminobutyric Acid; Humans; Male; Vigabatrin | 1997 |
Long-term treatment with vigabatrin - 10 years of clinical experience.
Topics: Anticonvulsants; Chronic Disease; Cohort Studies; Epilepsy; Female; Follow-Up Studies; gamma-Aminobu | 1999 |
The long-term use of gabapentin, lamotrigine, and vigabatrin in patients with chronic epilepsy.
Topics: Acetates; Ambulatory Care; Amines; Anticonvulsants; Chronic Disease; Clinical Trials as Topic; Cyclo | 1999 |
Possible analgesic effect of vigabatrin in animal experimental chronic neuropathic pain.
Topics: Analgesics; Animals; Anticonvulsants; Carbamazepine; Chronic Disease; Neuralgia; Phenytoin; Rats; Ra | 1999 |