vigabatrin has been researched along with Brain Injuries in 3 studies
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After three doses, median Cmax in microdialysates increased to 5." | 2.79 | Monitoring vigabatrin in head injury patients by cerebral microdialysis: obtaining pharmacokinetic measurements in a neurocritical care setting. ( Carpenter, KL; Hutchinson, PJ; Nortje, J; Shannon, RJ; Timofeev, I, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shannon, RJ | 1 |
| Timofeev, I | 2 |
| Nortje, J | 2 |
| Hutchinson, PJ | 2 |
| Carpenter, KL | 2 |
| Czosnyka, M | 1 |
| Pickard, JD | 1 |
| Curatolo, P | 1 |
| Bombardieri, R | 1 |
| Cerminara, C | 1 |
1 review available for vigabatrin and Brain Injuries
| Article | Year |
|---|---|
Current management for epilepsy in tuberous sclerosis complex.
Topics: Animals; Anticonvulsants; Brain Injuries; Cognition Disorders; Epilepsy; Humans; Neurosurgery; Tuber | 2006 |
2 trials available for vigabatrin and Brain Injuries
| Article | Year |
|---|---|
Monitoring vigabatrin in head injury patients by cerebral microdialysis: obtaining pharmacokinetic measurements in a neurocritical care setting.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Area Under Curve; Blood-Brain Barrier; Brain Injuries; Chr | 2014 |
A microdialysis study of oral vigabatrin administration in head injury patients: preliminary evaluation of multimodality monitoring.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amino Acids; Anticonvulsants; Blood Pressure; Brain C | 2012 |