vigabatrin has been researched along with Brain Disorders in 17 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vigabatrin (Sabril, Hoechst Marion Roussel) is an antiepilepsy drug (AED) presently marketed in 64 countries for the treatment of partial and secondarily generalized seizures." | 8.80 | The potential for vigabatrin-induced intramyelinic edema in humans. ( Brigell, MG; Cohen, JA; Fisher, RS; Peyster, RG; Sze, G, 2000) |
| "Vigabatrin (Sabril, Hoechst Marion Roussel) is an antiepilepsy drug (AED) presently marketed in 64 countries for the treatment of partial and secondarily generalized seizures." | 4.80 | The potential for vigabatrin-induced intramyelinic edema in humans. ( Brigell, MG; Cohen, JA; Fisher, RS; Peyster, RG; Sze, G, 2000) |
| "Vigabatrin is an effective antiepileptic drug (AED) for the treatment of refractory complex partial seizures (rCPS) and infantile spasms (IS)." | 2.47 | Non-vision adverse events with vigabatrin therapy. ( Kälviäinen, R; Walker, SD, 2011) |
| "Report a series of children with West syndrome (WS) treated with vigabatrin (VGB) who developed characteristic MRI alterations." | 1.72 | Vigabatrin-associated brain abnormalities on MRI and other neurological symptoms in patients with West syndrome. ( Calvo, A; Caraballo, RH; Crespo, A; Fassulo, L; Gallo, A; Pociecha, J; Princich, J; Reyes Valenzuela, G; Rugilo, C; Semprino, M, 2022) |
| "Introduccion." | 1.39 | [Characterisation of the paediatric population of Costa Rica with tuberous sclerosis and a description of the behaviour of the associated epilepsy]. ( Benavides-Lara, A; Hernández, L; Ulate-Campos, A, 2013) |
| "Vigabatrin (VGB) is a new-generation anticonvulsant used in the treatment of partial seizures and West syndrome." | 1.31 | Acute encephalopathy associated with vigabatrin in a six-month-old girl. ( Haas-Lude, K; Krägeloh-Mann, I; Niemann, G; Riethmüller, J; Wolff, M, 2000) |
| "Thus, the seizure-facilitating nigral efferents may be subject to inhibition by both GABA and opiates and may normally be driven by substance P." | 1.27 | Role of the substantia nigra in GABA-mediated anticonvulsant actions. ( Gale, K, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Reyes Valenzuela, G | 1 |
| Crespo, A | 1 |
| Princich, J | 1 |
| Fassulo, L | 1 |
| Semprino, M | 1 |
| Gallo, A | 1 |
| Rugilo, C | 1 |
| Pociecha, J | 1 |
| Calvo, A | 1 |
| Caraballo, RH | 1 |
| Bhalla, S | 1 |
| Skjei, K | 1 |
| Lotan, E | 1 |
| Bluvstein, J | 1 |
| Zan, E | 1 |
| Hernández Vega, Y | 1 |
| Kaliakatsos, M | 1 |
| U-King-Im, JM | 1 |
| Lascelles, K | 1 |
| Lim, M | 1 |
| Ulate-Campos, A | 1 |
| Benavides-Lara, A | 1 |
| Hernández, L | 1 |
| Cazorla, MR | 1 |
| Verdú, A | 1 |
| Montes, C | 1 |
| Ayuga, F | 1 |
| Nandhagopal, R | 1 |
| Thapa, M | 1 |
| Khanna, PC | 1 |
| Walker, SD | 1 |
| Kälviäinen, R | 1 |
| da Rocha, AJ | 1 |
| Reis, F | 1 |
| Gama, HP | 1 |
| da Silva, CJ | 1 |
| Braga, FT | 1 |
| Maia, AC | 1 |
| Cendes, F | 1 |
| Jackson, GD | 1 |
| Williams, SR | 1 |
| Weller, RO | 1 |
| van Bruggen, N | 1 |
| Preece, NE | 1 |
| Williams, SC | 1 |
| Butler, WH | 1 |
| Duncan, JS | 1 |
| Granström, ML | 1 |
| Gaily, E | 1 |
| Liukkonen, E | 1 |
| Cohen, JA | 1 |
| Fisher, RS | 1 |
| Brigell, MG | 1 |
| Peyster, RG | 1 |
| Sze, G | 1 |
| Haas-Lude, K | 1 |
| Wolff, M | 1 |
| Riethmüller, J | 1 |
| Niemann, G | 1 |
| Krägeloh-Mann, I | 1 |
| Qiao, M | 1 |
| Malisza, KL | 1 |
| Del Bigio, MR | 1 |
| Kozlowski, P | 1 |
| Seshia, SS | 1 |
| Tuor, UI | 1 |
| Gale, K | 1 |
| Pedersen, SA | 1 |
| Klosterskov, P | 1 |
| Gram, L | 1 |
| Dam, M | 1 |
3 reviews available for vigabatrin and Brain Disorders
| Article | Year |
|---|---|
Fulminant vigabatrin toxicity during combination therapy with adrenocorticotropic hormone for infantile spasms: Three cases and review of the literature.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Brain Diseases; Drug Therapy, Combination; Fatal Outco | 2020 |
Non-vision adverse events with vigabatrin therapy.
Topics: 4-Aminobutyrate Transaminase; Adolescent; Adult; Animals; Anticonvulsants; Brain Diseases; Cognition | 2011 |
The potential for vigabatrin-induced intramyelinic edema in humans.
Topics: Animals; Anticonvulsants; Brain; Brain Diseases; Clinical Trials as Topic; Dogs; Edema; Epilepsy; Ev | 2000 |
1 trial available for vigabatrin and Brain Disorders
| Article | Year |
|---|---|
Treatment of infantile spasms: results of a population-based study with vigabatrin as the first drug for spasms.
Topics: 4-Aminobutyrate Transaminase; Adrenocorticotropic Hormone; Anticonvulsants; Brain Diseases; Child; C | 1999 |
13 other studies available for vigabatrin and Brain Disorders
| Article | Year |
|---|---|
Vigabatrin-associated brain abnormalities on MRI and other neurological symptoms in patients with West syndrome.
Topics: Anticonvulsants; Brain; Brain Diseases; Child; Humans; Infant; Magnetic Resonance Imaging; Retrospec | 2022 |
Vigabatrin Toxicity in a Patient with Infantile Spasms Treated with Concomitant Hormonal Therapy.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Brain; Brain Diseases; Drug Therapy, Combination; Fema | 2020 |
Reversible vigabatrin-induced life-threatening encephalopathy.
Topics: Anticonvulsants; Brain; Brain Diseases; Female; Humans; Infant; Magnetic Resonance Imaging; Spasms, | 2014 |
[Characterisation of the paediatric population of Costa Rica with tuberous sclerosis and a description of the behaviour of the associated epilepsy].
Topics: Anticonvulsants; Autistic Disorder; Brain Diseases; Brain Neoplasms; Child, Preschool; Comorbidity; | 2013 |
Early infantile epileptic encephalopathy with unusual favourable outcome.
Topics: Anticonvulsants; Brain Diseases; Electroencephalography; Epilepsy; Female; Humans; Infant; Male; Pre | 2010 |
Coexistence of cerebral tubers with neurocysticercosis.
Topics: Anticonvulsants; Brain Diseases; Child; Humans; Incidental Findings; Male; Neurocysticercosis; Seizu | 2010 |
Vigabatrin-associated diffusion MRI abnormalities in tuberous sclerosis.
Topics: Brain; Brain Diseases; Diffusion Magnetic Resonance Imaging; Enzyme Inhibitors; Humans; Infant; Male | 2010 |
Focal transient lesion in the splenium of the corpus callosum in three non-epileptic patients.
Topics: Adult; Anticonvulsants; Brain Diseases; Corpus Callosum; Female; Humans; Magnetic Resonance Imaging; | 2006 |
Vigabatrin-induced lesions in the rat brain demonstrated by quantitative magnetic resonance imaging.
Topics: Animals; Anticonvulsants; Brain; Brain Diseases; Cerebellum; gamma-Aminobutyric Acid; Glial Fibrilla | 1994 |
Acute encephalopathy associated with vigabatrin in a six-month-old girl.
Topics: Acute Disease; Age Factors; Anticonvulsants; Brain Diseases; Electroencephalography; Female; Humans; | 2000 |
Effect of long-term vigabatrin administration on the immature rat brain.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Brain Diseases; Cell Death; Magnetic Resonance Im | 2000 |
Role of the substantia nigra in GABA-mediated anticonvulsant actions.
Topics: Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Brain Diseases; Denervation; D | 1986 |
Long-term study of gamma-vinyl GABA in the treatment of epilepsy.
Topics: Adolescent; Adult; Aged; Aminocaproates; Animals; Anticonvulsants; Brain Diseases; Child; Child, Pre | 1985 |