vigabatrin has been researched along with Body Weight in 13 studies
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two toxicologic studies of vigabatrin were conducted with immature Sprague Dawley rats to characterize intramyelinic edema (IME) formation and assess potential impact on behavioral measures." | 7.77 | Oral toxicity of vigabatrin in immature rats: characterization of intramyelinic edema. ( Bekersky, I; Collins, S; Garman, R; Jortner, B; Patterson, R; Sagar, S; Tolbert, D; Walzer, M; Wanaski, S, 2011) |
| "Vigabatrin is an inhibitor of γ-aminobutyric acid transaminase." | 5.40 | Population pharmacokinetics analysis of vigabatrin in adults and children with epilepsy and children with infantile spasms. ( Karim, A; Kowalski, KG; Nielsen, JC; Patel, M; Tolbert, D; Wesche, DL, 2014) |
| "Two toxicologic studies of vigabatrin were conducted with immature Sprague Dawley rats to characterize intramyelinic edema (IME) formation and assess potential impact on behavioral measures." | 3.77 | Oral toxicity of vigabatrin in immature rats: characterization of intramyelinic edema. ( Bekersky, I; Collins, S; Garman, R; Jortner, B; Patterson, R; Sagar, S; Tolbert, D; Walzer, M; Wanaski, S, 2011) |
| "several parameters, concerning fertility were measured in 40 albino male rats of Sprague Dawley strain, they were divided into 4 groups, group one received vehicle (distilled water), group two received Vigabatrin in a dose of 200 mg/kg body weight, group three received Lamotrigine in a dose of 30 mg/kg body weight, and group four received Gabapentin 100 mg/kg body weight." | 3.72 | The effect of Vigabatrin, Lamotrigine and Gabapentin on the fertility, weights, sex hormones and biochemical profiles of male rats. ( Abdul-Zahra, E; Bataineh, H; Daoud, AS; Otoom, S, 2004) |
| "Vigabatrin is an inhibitor of γ-aminobutyric acid transaminase." | 1.40 | Population pharmacokinetics analysis of vigabatrin in adults and children with epilepsy and children with infantile spasms. ( Karim, A; Kowalski, KG; Nielsen, JC; Patel, M; Tolbert, D; Wesche, DL, 2014) |
| "Vigabatrin dosages were identified for pediatric rCPS patients with body weights ≥10 kg." | 1.40 | Vigabatrin pediatric dosing information for refractory complex partial seizures: results from a population dose-response analysis. ( Kowalski, KG; Nielsen, JC; Patel, M; Tolbert, D; Wesche, DL, 2014) |
| " Oral dosing [3 mg/ml of drinking water, giving doses of GVG of 194 +/- 38 mg/kg/day and of EOS of 303 +/- 42 mg/kg/day (mean +/- SD)] was followed by microdialysis at 2, 8, and 21 days." | 1.29 | The effect of chronic treatment with the GABA transaminase inhibitors gamma-vinyl-GABA and ethanolamine-O-sulphate on the in vivo release of GABA from rat hippocampus. ( Fowler, LJ; Qume, M; Whitton, PS, 1995) |
| "Acute and chronic administration of vigabatrin, a selective inactivator of GABA-T, suppresses haloperidol-induced dyskinesias at low doses without preventing the enhancement of striatal dopamine D2 receptor density or the development of vacuous chewing movements." | 1.29 | Suppression of haloperidol-induced oral dyskinesias in rats by vigabatrin. ( Elands, J; Gobaille, S; Grauffel, C; Knödgen, B; Moran, P; Sarhan, S; Seiler, N; van den Buuse, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nielsen, JC | 2 |
| Kowalski, KG | 2 |
| Karim, A | 1 |
| Patel, M | 2 |
| Wesche, DL | 2 |
| Tolbert, D | 3 |
| DeMarco, A | 1 |
| Dalal, RM | 1 |
| Kahanda, M | 1 |
| Mullapudi, U | 1 |
| Pai, J | 1 |
| Hammel, C | 1 |
| Liebling, CN | 1 |
| Patel, V | 1 |
| Brodie, JD | 1 |
| Schiffer, WK | 1 |
| Dewey, SL | 1 |
| Aquilina, SD | 1 |
| Walzer, M | 1 |
| Bekersky, I | 1 |
| Wanaski, S | 1 |
| Collins, S | 1 |
| Jortner, B | 1 |
| Patterson, R | 1 |
| Garman, R | 1 |
| Sagar, S | 1 |
| Daoud, AS | 1 |
| Bataineh, H | 1 |
| Otoom, S | 1 |
| Abdul-Zahra, E | 1 |
| Lombardo, SA | 1 |
| Leanza, G | 1 |
| Meli, C | 1 |
| Lombardo, ME | 1 |
| Mazzone, L | 1 |
| Vincenti, I | 1 |
| Cioni, M | 1 |
| Lenicque, PM | 1 |
| Abdul Hai, C | 1 |
| Wepierre, J | 1 |
| Cohen, Y | 1 |
| Qume, M | 2 |
| Whitton, PS | 1 |
| Fowler, LJ | 2 |
| Seiler, N | 1 |
| Grauffel, C | 1 |
| Elands, J | 1 |
| van den Buuse, M | 1 |
| Knödgen, B | 1 |
| Sarhan, S | 1 |
| Moran, P | 1 |
| Gobaille, S | 1 |
| Gupta, M | 1 |
| Greven, R | 1 |
| Jansen, EE | 1 |
| Jakobs, C | 1 |
| Hogema, BM | 1 |
| Froestl, W | 1 |
| Snead, OC | 1 |
| Bartels, H | 1 |
| Grompe, M | 1 |
| Gibson, KM | 1 |
| Singewald, N | 1 |
| Pfitscher, A | 1 |
| Philippu, A | 1 |
| Persson, LI | 1 |
| Rönnbäck, L | 1 |
| Ben-Menachem, E | 1 |
| Eriksson, P | 1 |
| Nilsson, M | 1 |
13 other studies available for vigabatrin and Body Weight
| Article | Year |
|---|---|
Population pharmacokinetics analysis of vigabatrin in adults and children with epilepsy and children with infantile spasms.
Topics: Adult; Body Weight; Child; Child, Preschool; Enzyme Inhibitors; Epilepsy; Female; gamma-Aminobutyric | 2014 |
Vigabatrin pediatric dosing information for refractory complex partial seizures: results from a population dose-response analysis.
Topics: Adult; Anticonvulsants; Body Weight; Chemistry, Pharmaceutical; Child; Child, Preschool; Community H | 2014 |
Subchronic racemic gamma vinyl-GABA produces weight loss in Sprague Dawley and Zucker fatty rats.
Topics: Age Factors; Animals; Body Weight; Chronotherapy; Injections, Intraperitoneal; Male; Obesity; Rats; | 2008 |
Oral toxicity of vigabatrin in immature rats: characterization of intramyelinic edema.
Topics: Administration, Oral; Age Factors; Animals; Behavior, Animal; Body Weight; Brain; Dose-Response Rela | 2011 |
The effect of Vigabatrin, Lamotrigine and Gabapentin on the fertility, weights, sex hormones and biochemical profiles of male rats.
Topics: Amines; Analgesics; Animals; Antimanic Agents; Body Weight; Cyclohexanecarboxylic Acids; Female; Fer | 2004 |
Maternal exposure to the antiepileptic drug vigabatrin affects postnatal development in the rat.
Topics: Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Birth Weight; Body Weight; Brain Chemi | 2005 |
Time course relation between neurotoxic effects of kainic acid on behaviour and brain GABA-levels. Protection by gamma-vinyl GABA.
Topics: Aminocaproates; Animals; Behavior, Animal; Body Weight; Brain Chemistry; gamma-Aminobutyric Acid; Ka | 1983 |
The effect of chronic treatment with the GABA transaminase inhibitors gamma-vinyl-GABA and ethanolamine-O-sulphate on the in vivo release of GABA from rat hippocampus.
Topics: 4-Aminobutyrate Transaminase; Animals; Behavior, Animal; Body Weight; Calcium; Drinking; Ethanolamin | 1995 |
Suppression of haloperidol-induced oral dyskinesias in rats by vigabatrin.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Body Weight; Brain; Dyskinesia, Drug-Induced | 1995 |
Effect of chronic treatment with the GABA transaminase inhibitors gamma-vinyl GABA and ethanolamine O-sulphate on the in vitro GABA release from rat hippocampus.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Animals; Behavior, Animal; Body Weight; Brain Chemistry; | 1997 |
Therapeutic intervention in mice deficient for succinate semialdehyde dehydrogenase (gamma-hydroxybutyric aciduria).
Topics: Aldehyde Oxidoreductases; Animals; Benzocycloheptenes; Body Weight; gamma-Aminobutyric Acid; Genotyp | 2002 |
Effects of gamma-vinyl GABA (vigabatrin) on blood pressure and body weight of hypertensive and normotensive rats.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Blood Pressure; Body Weight; Brain; gamma-Ami | 1992 |
Changes in CSF and brain soluble proteins following vigabatrin treatment in rats.
Topics: Aminocaproates; Animals; Anticonvulsants; Body Weight; Brain; Brain Chemistry; Cerebrospinal Fluid P | 1989 |