vigabatrin has been researched along with Alcohol Abuse in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We enrolled 120 patients with alcohol use disorder who were randomly assigned to either treatment with vigabatrin (2g/day for 4 days) or placebo." | 3.30 | A Placebo-Controlled Randomized Trial of Vigabatrin in the Management of Acute Alcohol Withdrawal. ( Bonomo, Y; Collins, L; Lloyd-Jones, M; Norman, A; O'Neill, H; Ogden, E; Pastor, A; Williams, J, 2023) |
| "Cocaine dependence is associated with severe medical, psychiatric, and social morbidity, but no pharmacotherapy is approved for its treatment in the United States." | 2.74 | Randomized, double-blind, placebo-controlled trial of vigabatrin for the treatment of cocaine dependence in Mexican parolees. ( Brodie, JD; Case, BG; Dewey, SL; Figueroa, E; Laska, EM; Robinson, JA; Wanderling, JA, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Williams, J | 1 |
| Collins, L | 1 |
| Norman, A | 1 |
| O'Neill, H | 1 |
| Lloyd-Jones, M | 1 |
| Ogden, E | 1 |
| Bonomo, Y | 1 |
| Pastor, A | 1 |
| Brodie, JD | 1 |
| Case, BG | 1 |
| Figueroa, E | 1 |
| Dewey, SL | 1 |
| Robinson, JA | 1 |
| Wanderling, JA | 1 |
| Laska, EM | 1 |
| Brady, KT | 2 |
| Stuppaeck, CH | 1 |
| Deisenhammer, EA | 1 |
| Kurz, M | 1 |
| Whitworth, AB | 1 |
| Hinterhuber, H | 1 |
| Myrick, H | 1 |
| Malcolm, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-Blind, Randomized, Placebo- Controlled Trial of Vigabatrin for Short Term Abstinence From Cocaine in Cocaine Dependent Parolees[NCT00527683] | Phase 2 | 100 participants (Actual) | Interventional | 2007-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for vigabatrin and Alcohol Abuse
| Article | Year |
|---|---|
New developments in the pharmacotherapy of alcohol dependence.
Topics: Acamprosate; Adjuvants, Anesthesia; Alcohol Deterrents; Alcoholism; Anticonvulsants; Buspirone; Carb | 2001 |
2 trials available for vigabatrin and Alcohol Abuse
| Article | Year |
|---|---|
A Placebo-Controlled Randomized Trial of Vigabatrin in the Management of Acute Alcohol Withdrawal.
Topics: Alcoholism; Benzodiazepines; Diazepam; Double-Blind Method; Humans; Substance Withdrawal Syndrome; V | 2023 |
Randomized, double-blind, placebo-controlled trial of vigabatrin for the treatment of cocaine dependence in Mexican parolees.
Topics: Adult; Alcoholism; Anticonvulsants; Cocaine-Related Disorders; Combined Modality Therapy; Double-Bli | 2009 |
2 other studies available for vigabatrin and Alcohol Abuse
| Article | Year |
|---|---|
Expanding treatment options for cocaine dependence.
Topics: Adult; Alcoholism; Animals; Cocaine-Related Disorders; Disease Models, Animal; Drug Approval; Drug-R | 2009 |
The irreversible gamma-aminobutyrate transaminase inhibitor vigabatrin in the treatment of the alcohol withdrawal syndrome.
Topics: 4-Aminobutyrate Transaminase; Adult; Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Elect | 1996 |