vigabatrin has been researched along with Absence Seizure Disorder in 20 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-five patients with epilepsy (mostly with partial seizures) who had responded favourably to a short-term trial of add-on vigabatrin entered maintenance treatment." | 7.68 | Six-year follow-up study on the efficacy and safety of vigabatrin in patients with epilepsy. ( Galimberti, CA; Iudice, A; Manni, R; Morini, R; Mumford, JP; Perucca, E; Tartara, A, 1992) |
| "Vigabatrin is a specific and irreversible inhibitor of the enzyme gamma-amino-butyric-acid (GABA) transferase." | 6.39 | [Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic]. ( Krämer, G; Vogt, H, 1995) |
| "Twenty-five patients with epilepsy (mostly with partial seizures) who had responded favourably to a short-term trial of add-on vigabatrin entered maintenance treatment." | 3.68 | Six-year follow-up study on the efficacy and safety of vigabatrin in patients with epilepsy. ( Galimberti, CA; Iudice, A; Manni, R; Morini, R; Mumford, JP; Perucca, E; Tartara, A, 1992) |
| "Vigabatrin, because of its ability to increase brain GABA concentration, acts as an anticonvulsant on convulsive epileptic seizures and increases seizures in generalized non-convulsive epilepsy." | 3.68 | Potentiation of gamma-vinyl GABA (vigabatrin) effects by glycine. ( Depaulis, A; Liu, Z; Marescaux, C; Seiler, N; Vergnes, M, 1990) |
| "Vigabatrin is a specific and irreversible inhibitor of the enzyme gamma-amino-butyric-acid (GABA) transferase." | 2.39 | [Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic]. ( Krämer, G; Vogt, H, 1995) |
| "Epileptic seizures can be difficult to recognize in infancy and childhood because the semeiology can be misleading." | 1.35 | [Epileptic seizures in childhood: from seizure type to diagnosis]. ( Chabrol, B; Hugonencq, C; Mancini, J; Milh, M; Ticus, I; Villeneuve, N, 2008) |
| "Vigabatrin was used with the aim of enhancing GABAergic neurotransmission, and in this way to investigate the role of this process in the properties of SWDs." | 1.34 | GABAergic mechanisms in absence epilepsy: a computational model of absence epilepsy simulating spike and wave discharges after vigabatrin in WAG/Rij rats. ( Bouwman, BM; Lopes da Silva, FH; Maris, E; Suffczynski, P; van Rijn, CM, 2007) |
| "Vigabatrin was also used in the treatment of two children." | 1.30 | Inappropriate use of carbamazepine and vigabatrin in typical absence seizures. ( Agathonikou, A; Panayiotopoulos, CP; Parker, AP; Robinson, RO, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 11 (55.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perescis, MFJ | 1 |
| van Luijtelaar, G | 2 |
| van Rijn, CM | 3 |
| Pawluski, JL | 1 |
| Kuchenbuch, M | 1 |
| Hadjadj, S | 1 |
| Dieuset, G | 1 |
| Costet, N | 1 |
| Vercueil, L | 1 |
| Biraben, A | 1 |
| Martin, B | 1 |
| Yang, MT | 1 |
| Lee, WT | 1 |
| Chu, LW | 1 |
| Shen, YZ | 1 |
| Maris, E | 2 |
| Bouwman, BM | 2 |
| Suffczynski, P | 2 |
| Bosnyakova, D | 1 |
| Gabova, A | 1 |
| Kuznetsova, G | 1 |
| Obukhov, Y | 1 |
| Midzyanovskaya, I | 1 |
| Salonin, D | 1 |
| van Rijn, C | 1 |
| Coenen, A | 1 |
| Tuomisto, L | 1 |
| Lopes da Silva, FH | 1 |
| Milh, M | 1 |
| Ticus, I | 1 |
| Villeneuve, N | 1 |
| Hugonencq, C | 1 |
| Mancini, J | 1 |
| Chabrol, B | 1 |
| Vergnes, M | 4 |
| Marescaux, C | 4 |
| Micheletti, G | 2 |
| Depaulis, A | 3 |
| Rumbach, L | 2 |
| Warter, JM | 2 |
| Vogt, H | 1 |
| Krämer, G | 1 |
| Cocito, L | 2 |
| Maffini, M | 1 |
| Loeb, C | 1 |
| Snead, OC | 1 |
| Liu, CC | 1 |
| Hosford, DA | 1 |
| Wang, Y | 1 |
| Panayiotopoulos, CP | 3 |
| Agathonikou, A | 2 |
| Sharoqi, IA | 1 |
| Parker, AP | 2 |
| Robinson, RO | 1 |
| Primavera, A | 1 |
| Tartara, A | 1 |
| Manni, R | 1 |
| Galimberti, CA | 1 |
| Morini, R | 1 |
| Mumford, JP | 1 |
| Iudice, A | 1 |
| Perucca, E | 1 |
| Liu, Z | 2 |
| Seiler, N | 1 |
1 review available for vigabatrin and Absence Seizure Disorder
| Article | Year |
|---|---|
[Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic].
Topics: 4-Aminobutyrate Transaminase; Adult; Anticonvulsants; Child; Drug Therapy, Combination; Epilepsies, | 1995 |
1 trial available for vigabatrin and Absence Seizure Disorder
| Article | Year |
|---|---|
Vigabatrin in chronic epilepsy: a 7-year follow-up study of responder patients.
Topics: Adolescent; Adult; Aminocaproates; Anticonvulsants; Drug Therapy, Combination; Electroencephalograph | 1993 |
18 other studies available for vigabatrin and Absence Seizure Disorder
| Article | Year |
|---|---|
Immediate versus late effects of vigabatrin on spike and wave discharges.
Topics: Animals; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Frontal Lobe; Male; Neur | 2020 |
Long-term negative impact of an inappropriate first antiepileptic medication on the efficacy of a second antiepileptic medication in mice.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; | 2018 |
Anti-epileptic drugs-induced de novo absence seizures.
Topics: Anticonvulsants; Carbamazepine; Child; Electroencephalography; Epilepsy, Absence; Epilepsy, Complex | 2003 |
Starting and stopping mechanisms of absence epileptic seizures are revealed by hazard functions.
Topics: Algorithms; Animals; Anticonvulsants; Data Interpretation, Statistical; Electroencephalography; Epil | 2006 |
Time-frequency analysis of spike-wave discharges using a modified wavelet transform.
Topics: Algorithms; Anesthetics, Dissociative; Animals; Anti-Allergic Agents; Anticonvulsants; Data Interpre | 2006 |
GABAergic mechanisms in absence epilepsy: a computational model of absence epilepsy simulating spike and wave discharges after vigabatrin in WAG/Rij rats.
Topics: Action Potentials; Animals; Animals, Genetically Modified; Anticonvulsants; Brain; Computer Simulati | 2007 |
[Epileptic seizures in childhood: from seizure type to diagnosis].
Topics: Adolescent; Age Factors; Anticonvulsants; Child; Diagnosis, Differential; Electroencephalography; Ep | 2008 |
Enhancement of spike and wave discharges by GABAmimetic drugs in rats with spontaneous petit-mal-like epilepsy.
Topics: Action Potentials; Aminocaproates; Animals; Baclofen; Epilepsy, Absence; gamma-Aminobutyric Acid; Is | 1984 |
GABAA receptor function in the gamma-hydroxybutyrate model of generalized absence seizures.
Topics: Aminocaproates; Animals; Anticonvulsants; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicycl | 1993 |
Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dru | 1997 |
Vigabatrin aggravates absences and absence status.
Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; gamma-Amin | 1997 |
Inappropriate use of carbamazepine and vigabatrin in typical absence seizures.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsies, Myoclon | 1998 |
Vigabatrin aggravates absences and absence status.
Topics: Adult; Anticonvulsants; Asphyxia; Brain Damage, Chronic; Carbamazepine; Drug Therapy, Combination; E | 1998 |
Importance of specifying the type of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Contraindications; Diagnosis, Differential; Epilepsies, Parti | 1999 |
Six-year follow-up study on the efficacy and safety of vigabatrin in patients with epilepsy.
Topics: Adolescent; Adult; Aminocaproates; Anticonvulsants; Brain Stem; Cerebral Cortex; Electroencephalogra | 1992 |
Evidence for a critical role of GABAergic transmission within the thalamus in the genesis and control of absence seizures in the rat.
Topics: Aminocaproates; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, | 1991 |
Potentiation of gamma-vinyl GABA (vigabatrin) effects by glycine.
Topics: 3-Mercaptopropionic Acid; Acoustic Stimulation; Aminocaproates; Animals; Anticonvulsants; Drug Syner | 1990 |
Diazepam antagonizes GABAmimetics in rats with spontaneous petit mal-like epilepsy.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Cycloserine; Diazepam; Epilepsy, Absence; Iso | 1985 |