vicenin-ii and Colorectal-Neoplasms

vicenin-ii has been researched along with Colorectal-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for vicenin-ii and Colorectal-Neoplasms

ArticleYear
Vicenin-2 inhibits Wnt/β-catenin signaling and induces apoptosis in HT-29 human colon cancer cell line.
    Drug design, development and therapy, 2018, Volume: 12

    MTT assay was used to assess the cell viability at different concentrations and time point. Vicenin-2 at a concentration of 50 µM (IC. Further, Vincenin-2 reduced the T-cell factor (TCF) / Leukocyte erythroid factor (LEF) reporter activity in HT-29 cells. Vicenin-2 also promoted substantial cell cycle arrest at the G. Together, these results revealed that Vicenin-2 can act as a potent inhibitor of HT-29 cell proliferation and can be used as an agent against CRC.

    Topics: Antineoplastic Agents, Phytogenic; Apigenin; Apoptosis; beta Catenin; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Glucosides; HT29 Cells; Humans; Structure-Activity Relationship; Tumor Cells, Cultured; Wnt Signaling Pathway

2018