vesnarinone has been researched along with Neutropenia in 5 studies
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the maximum-tolerated dose, dose-limiting toxicities (DLTs), and pharmacokinetic profile of vesnarinone given once daily in combination with gemcitabine." | 2.69 | Phase I and pharmacokinetic study of the differentiating agent vesnarinone in combination with gemcitabine in patients with advanced cancer. ( Drengler, RL; Eckhardt, SG; Felton, SA; Garner, AM; Hammond, LA; Hidalgo, M; Mallikaarjun, S; Patnaik, A; Rowinsky, EK; Siu, LL; Tammara, BK; Von Hoff, DD, 2000) |
| "This article reviews the precautions and adverse effects associated with vesnarinone use, and the potential mechanisms responsible for these complications as well as suggested treatment strategies." | 2.42 | Precautions for use and adverse effects of vesnarinone: potential mechanisms and future therapies. ( Bertolet, BD, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bertolet, BD | 2 |
| White, BG | 1 |
| Pepine, CJ | 1 |
| Sato, Y | 1 |
| Matsumori, A | 1 |
| Sasayama, S | 1 |
| Vander Heide, RS | 1 |
| Marsh, JD | 1 |
| Patnaik, A | 1 |
| Rowinsky, EK | 1 |
| Tammara, BK | 1 |
| Hidalgo, M | 1 |
| Drengler, RL | 1 |
| Garner, AM | 1 |
| Siu, LL | 1 |
| Hammond, LA | 1 |
| Felton, SA | 1 |
| Mallikaarjun, S | 1 |
| Von Hoff, DD | 1 |
| Eckhardt, SG | 1 |
1 review available for vesnarinone and Neutropenia
| Article | Year |
|---|---|
Precautions for use and adverse effects of vesnarinone: potential mechanisms and future therapies.
Topics: Animals; Clinical Trials as Topic; Death, Sudden; Heart Failure; Humans; Monitoring, Physiologic; Mu | 2004 |
1 trial available for vesnarinone and Neutropenia
| Article | Year |
|---|---|
Phase I and pharmacokinetic study of the differentiating agent vesnarinone in combination with gemcitabine in patients with advanced cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Differentiation; Deoxyc | 2000 |
3 other studies available for vesnarinone and Neutropenia
| Article | Year |
|---|---|
Neutropenia occurring during treatment with vesnarinone (OPC-8212).
Topics: Cardiomyopathy, Dilated; Cardiotonic Agents; Clinical Trials as Topic; Europe; Female; Granulocyte C | 1994 |
Inotropic agent vesnarinone inhibits cytokine production and E-selectin expression in human umbilical vein endothelial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amrinone; Cardiotonic Agents; Cell Adhesion; Cells, Cultured | 1995 |
Through the looking glass: a positive inotropic drug and ischemic preconditioning.
Topics: 5'-Nucleotidase; Adenosine; Animals; Cardiotonic Agents; Dogs; Drug Approval; Enzyme Activation; Hea | 1997 |