vesamicol has been researched along with Parkinson Disease in 3 studies
vesamicol: RN given refers to parent cpd; structure
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "[3H]Vesamicol binding was characterized in human brain post mortem." | 1.28 | Choline acetyltransferase activity and [3H]vesamicol binding in the temporal cortex of patients with Alzheimer's disease, Parkinson's disease, and rats with basal forebrain lesions. ( Agid, Y; Brice, A; Duyckaerts, C; Hauw, JJ; LeMoal, M; Mayo, W; Ruberg, M; Simon, H, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frey, KA | 1 |
| Wieland, DM | 1 |
| Kilbourn, MR | 1 |
| Kish, SJ | 1 |
| Distefano, LM | 1 |
| Dozic, S | 1 |
| Robitaille, Y | 1 |
| Rajput, A | 1 |
| Deck, JH | 1 |
| Hornykiewicz, O | 1 |
| Ruberg, M | 1 |
| Mayo, W | 1 |
| Brice, A | 1 |
| Duyckaerts, C | 1 |
| Hauw, JJ | 1 |
| Simon, H | 1 |
| LeMoal, M | 1 |
| Agid, Y | 1 |
3 other studies available for vesamicol and Parkinson Disease
| Article | Year |
|---|---|
Imaging of monoaminergic and cholinergic vesicular transporters in the brain.
Topics: Acetylcholine; Alzheimer Disease; Brain; Carbon Radioisotopes; Carrier Proteins; Humans; Membrane Gl | 1998 |
[3H]vesamicol binding in human brain cholinergic deficiency disorders.
Topics: Acetylcholine; Adult; Aged; Alzheimer Disease; Amygdala; Autonomic Nervous System Diseases; Brain Ch | 1990 |
Choline acetyltransferase activity and [3H]vesamicol binding in the temporal cortex of patients with Alzheimer's disease, Parkinson's disease, and rats with basal forebrain lesions.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Brain Injuries; Choline O-Acetyltransferase; Fe | 1990 |