versicolorin-a and Liver-Neoplasms

versicolorin-a has been researched along with Liver-Neoplasms* in 1 studies

Reviews

1 review(s) available for versicolorin-a and Liver-Neoplasms

ArticleYear
Biological reactive intermediates of bisfuranoid mycotoxins.
    The Journal of toxicological sciences, 1990, Volume: 15 Suppl 4

    Based on the mode of action of AFB1 and the activities of its biologically active intermediates, one may conclude that: 1. The mode of toxic action of the bisfuranoid mycotoxin is through epoxidation of the vinyl ether double bond of their dihydrobisfuran functionality. 2. The DNA and plasma albumin adducts formed in vivo may be useful in the molecular dosimetry of these environmental carcinogens. 3. Monitoring of these adducts of AFB1 in biological samples so far indicates that aflatoxin is likely involved in the etiology of human liver cancer.

    Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; Animals; Anthraquinones; DNA; Humans; Liver Neoplasms; Mice; Mutagenesis; Mycotoxins; Rats; Serum Albumin; Sterigmatocystin

1990