verapamil has been researched along with Uterine Neoplasms in 7 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Uterine Neoplasms: Tumors or cancer of the UTERUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of multi-drug resistance (MDR1) and its product, P-glycoprotein (P-gp) on 5-aminolevulinic acid hexyl ester (Hexyl-ALA) mediated phototoxicity was determined with human uterine sarcoma cells, MES-SA control and MDR1 expressing MES-SA-Dx5." | 7.74 | Effects of photoactivated 5-aminolevulinic acid hexyl ester on MDR1 over-expressing human uterine sarcoma cells. ( Chu, ES; Ho, RJ; Shi, M; Yow, CM, 2008) |
| "We investigated transport systems for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR, using a range of structurally similar compounds to determine whether these thyroid hormones are transported by common or different mechanisms." | 7.70 | Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA, 2000) |
| "The role of multi-drug resistance (MDR1) and its product, P-glycoprotein (P-gp) on 5-aminolevulinic acid hexyl ester (Hexyl-ALA) mediated phototoxicity was determined with human uterine sarcoma cells, MES-SA control and MDR1 expressing MES-SA-Dx5." | 3.74 | Effects of photoactivated 5-aminolevulinic acid hexyl ester on MDR1 over-expressing human uterine sarcoma cells. ( Chu, ES; Ho, RJ; Shi, M; Yow, CM, 2008) |
| "We investigated transport systems for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR, using a range of structurally similar compounds to determine whether these thyroid hormones are transported by common or different mechanisms." | 3.70 | Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA, 2000) |
| "The present study was performed to compare the cardiovascular adverse effects of verapamil, KR30031 and their optical isomers, and also to measure their ability to overcome multidrug resistance (MDR)." | 1.32 | Differential effects of the optical isomers of KR30031 on cardiotoxicity and on multidrug resistance reversal activity. ( Choi, SU; Kwon, MJ; Lee, BH; Lee, CO; Yi, KY; Yoo, SE, 2003) |
| "Verapamil has been shown to reverse acquired drug resistance to Adriamycin (ADR) and vinblastine in the P388 leukemia and Ehrlich ascites carcinoma model systems." | 1.27 | Effect of verapamil on in vitro cytotoxicity of adriamycin and vinblastine in human tumor cells. ( Cox, TC; Crowley, J; Goodman, GE; Yen, YP, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, BH | 1 |
| Lee, CO | 1 |
| Kwon, MJ | 1 |
| Yi, KY | 1 |
| Yoo, SE | 1 |
| Choi, SU | 1 |
| Pósa, SP | 1 |
| Dargó, G | 1 |
| Nagy, S | 1 |
| Kisszékelyi, P | 1 |
| Garádi, Z | 1 |
| Hámori, L | 1 |
| Szakács, G | 1 |
| Kupai, J | 1 |
| Tóth, S | 1 |
| Tcherniuk, SO | 1 |
| Oleinikov, AV | 1 |
| Chu, ES | 1 |
| Yow, CM | 1 |
| Shi, M | 1 |
| Ho, RJ | 1 |
| Powell, KA | 1 |
| Mitchell, AM | 1 |
| Manley, SW | 1 |
| Mortimer, RH | 2 |
| Goodman, GE | 1 |
| Yen, YP | 1 |
| Cox, TC | 1 |
| Crowley, J | 1 |
| Harker, WG | 1 |
| Bauer, D | 1 |
| Etiz, BB | 1 |
| Newman, RA | 1 |
| Sikic, BI | 1 |
7 other studies available for verapamil and Uterine Neoplasms
| Article | Year |
|---|---|
Differential effects of the optical isomers of KR30031 on cardiotoxicity and on multidrug resistance reversal activity.
Topics: Animals; Antineoplastic Agents; Aorta; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bloo | 2003 |
Cytotoxicity of cinchona alkaloid organocatalysts against MES-SA and MES-SA/Dx5 multidrug-resistant uterine sarcoma cell lines.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cinchona Alkaloids; Doxor | 2022 |
Pgp efflux pump decreases the cytostatic effect of CENP-E inhibitor GSK923295.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfami | 2015 |
Effects of photoactivated 5-aminolevulinic acid hexyl ester on MDR1 over-expressing human uterine sarcoma cells.
Topics: Aminolevulinic Acid; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter | 2008 |
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR.
Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenas | 2000 |
Effect of verapamil on in vitro cytotoxicity of adriamycin and vinblastine in human tumor cells.
Topics: Breast Neoplasms; Cell Survival; Clone Cells; Colonic Neoplasms; Doxorubicin; Drug Resistance; Esoph | 1987 |
Verapamil-mediated sensitization of doxorubicin-selected pleiotropic resistance in human sarcoma cells: selectivity for drugs which produce DNA scission.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Doxorubicin; Drug Resistance; Drug Synergi | 1986 |