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verapamil and Ureteral Obstruction

verapamil has been researched along with Ureteral Obstruction in 4 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Ureteral Obstruction: Blockage in any part of the URETER causing obstruction of urine flow from the kidney to the URINARY BLADDER. The obstruction may be congenital, acquired, unilateral, bilateral, complete, partial, acute, or chronic. Depending on the degree and duration of the obstruction, clinical features vary greatly such as HYDRONEPHROSIS and obstructive nephropathy.

Research Excerpts

ExcerptRelevanceReference
"The expression of p53, Fas and PCNA molecules is associated with long-term partial ureteral obstruction, whereas verapamil seems to be a protective agent against apoptotic changes."7.74Verapamil attenuates renal tubular apoptosis in response to partial unilateral ureteral obstruction. ( Erbagci, A; Erturhan, S; Topcu, SO; Ucak, R; Yagci, F, 2008)
"We examined the effect of a calcium channel blocker (verapamil) on renal functions and the abundance of apoptotic (p53, Fas, proliferating cell nuclear antigen [PCNA]) markers 1 week after Unilateral Ureteral Obstruction (UUO)."7.74Verapamil prevents the apoptotic and hemodynamic changes in response to unilateral ureteral obstruction. ( Celik, S; Erbagci, A; Erturhan, S; Topcu, SO; Ucak, R; Yagci, F, 2008)
"We examined the effect of a calcium channel blocker (verapamil) on renal functions and the abundance of apoptotic (p53, Fas, proliferating cell nuclear antigen [PCNA]) markers 1 week after Unilateral Ureteral Obstruction (UUO)."3.74Verapamil prevents the apoptotic and hemodynamic changes in response to unilateral ureteral obstruction. ( Celik, S; Erbagci, A; Erturhan, S; Topcu, SO; Ucak, R; Yagci, F, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Qing, Z1
Yuan, W1
Wang, J1
Song, W1
Luo, J1
Wu, X1
Lu, Q1
Li, Y1
Zeng, M1
Topcu, SO2
Erbagci, A2
Erturhan, S2
Yagci, F2
Ucak, R2
Celik, S1
Kahn, SA1
Gulmi, FA1
Chou, SY1
Mooppan, UM1
Kim, H1

Other Studies

4 other studies available for verapamil and Ureteral Obstruction

ArticleYear
Verapamil inhibited the development of ureteral stricture by blocking CaMK II-mediated STAT3 and Smad3/JunD pathways.
    International urology and nephrology, 2022, Volume: 54, Issue:11

    Topics: Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Collagen; Collagen Typ

2022
Verapamil attenuates renal tubular apoptosis in response to partial unilateral ureteral obstruction.
    Urologia internationalis, 2008, Volume: 80, Issue:1

    Topics: Animals; Apoptosis; Cell Proliferation; fas Receptor; Gene Expression Regulation; Immunohistochemist

2008
Verapamil prevents the apoptotic and hemodynamic changes in response to unilateral ureteral obstruction.
    International journal of urology : official journal of the Japanese Urological Association, 2008, Volume: 15, Issue:4

    Topics: Animals; Apoptosis; Calcium Channel Blockers; fas Receptor; Hemodynamics; Kidney; Kidney Tubules; Ma

2008
Contribution of endothelin-1 to renal vasoconstriction in unilateral ureteral obstruction: reversal by verapamil.
    The Journal of urology, 1997, Volume: 157, Issue:5

    Topics: Animals; Blood Pressure; Dogs; Endothelin-1; Female; Regional Blood Flow; Ureteral Obstruction; Vaso

1997