verapamil has been researched along with Tuberculosis, Multidrug-Resistant in 9 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Tuberculosis, Multidrug-Resistant: Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.
Excerpt | Relevance | Reference |
---|---|---|
"Verapamil and reserpine were included to determine their effect on rifampicin and ofloxacin susceptibility." | 1.37 | Rifampicin reduces susceptibility to ofloxacin in rifampicin-resistant Mycobacterium tuberculosis through efflux. ( Gey van Pittius, NC; Grobbelaar, M; Hernandez-Pando, R; Jimenez, A; Leon, R; Louw, GE; McEvoy, CR; Murray, M; van Helden, PD; Victor, TC; Warren, RM, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 6 (66.67) | 24.3611 |
2020's | 3 (33.33) | 2.80 |
Authors | Studies |
---|---|
Özgür, D | 1 |
Ersoy, L | 1 |
Ülger, M | 1 |
Tezcan Ülger, S | 1 |
Aslan, G | 1 |
Mushtaq, F | 1 |
Raza, SM | 1 |
Ahmad, A | 1 |
Aslam, H | 1 |
Adeel, A | 1 |
Saleem, S | 1 |
Ahmad, I | 1 |
de Souza, JVP | 1 |
Murase, LS | 2 |
Caleffi-Ferracioli, KR | 3 |
Palomo, CT | 1 |
de Lima Scodro, RB | 1 |
Siqueira, VLD | 1 |
Pavan, FR | 2 |
Cardoso, RF | 3 |
de Souza, JV | 1 |
Canezin, PH | 2 |
Scodro, RB | 2 |
Ld Siqueira, V | 1 |
Gupta, S | 1 |
Cohen, KA | 1 |
Winglee, K | 1 |
Maiga, M | 1 |
Diarra, B | 1 |
Bishai, WR | 1 |
Demitto, Fde O | 1 |
do Amaral, RC | 1 |
Maltempe, FG | 1 |
Siqueira, VL | 1 |
Lopes, MA | 1 |
Ramos, DF | 1 |
Almeida da Silva, PE | 1 |
Louw, GE | 1 |
Warren, RM | 1 |
Gey van Pittius, NC | 1 |
Leon, R | 1 |
Jimenez, A | 1 |
Hernandez-Pando, R | 1 |
McEvoy, CR | 1 |
Grobbelaar, M | 1 |
Murray, M | 1 |
van Helden, PD | 1 |
Victor, TC | 1 |
Machado, D | 1 |
Couto, I | 1 |
Perdigão, J | 1 |
Rodrigues, L | 1 |
Portugal, I | 1 |
Baptista, P | 1 |
Veigas, B | 1 |
Amaral, L | 1 |
Viveiros, M | 1 |
9 other studies available for verapamil and Tuberculosis, Multidrug-Resistant
Article | Year |
---|---|
[Investigation of Efflux Pump Genes in Resistant Mycobacterium tuberculosis Complex Clinical Isolates Exposed to First Line Antituberculosis Drugs and Verapamil Combination].
Topics: Antitubercular Agents; Bacterial Proteins; DNA, Complementary; Humans; Isoniazid; Microbial Sensitiv | 2023 |
Antimicrobial drug resistant features of Mycobacterium tuberculosis associated with treatment failure.
Topics: Amikacin; Antitubercular Agents; Humans; Isoniazid; Linezolid; Microbial Sensitivity Tests; Moxiflox | 2023 |
Isoniazid and verapamil modulatory activity and efflux pump gene expression in
Topics: Antitubercular Agents; Bacterial Proteins; Gene Expression; Humans; Isoniazid; Membrane Transport Pr | 2020 |
Modulatory effects of verapamil in rifampicin activity against Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Brazil; Catalase; DNA-Directed RNA Polymerases; Drug Resi | 2019 |
Efflux inhibition with verapamil potentiates bedaquiline in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Diarylquinolines; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tu | 2014 |
In vitro activity of rifampicin and verapamil combination in multidrug-resistant mycobacterium tuberculosis.
Topics: Antibiotics, Antitubercular; Calcium Channel Blockers; Drug Resistance, Multiple, Bacterial; Ethidiu | 2015 |
Antimycobacterial activity of usnic acid against resistant and susceptible strains of Mycobacterium tuberculosis and non-tuberculous mycobacteria.
Topics: Anti-Bacterial Agents; Benzofurans; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydraz | 2010 |
Rifampicin reduces susceptibility to ofloxacin in rifampicin-resistant Mycobacterium tuberculosis through efflux.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacterial | 2011 |
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Biological Transport, Active; Carrier Proteins; Catalase; | 2012 |