Page last updated: 2024-10-24

verapamil and Syncope

verapamil has been researched along with Syncope in 18 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)

Research Excerpts

ExcerptRelevanceReference
"Three of 15 patients with a history of cardiac arrest or syncope had ventricular tachycardia on ambulatory ECG monitoring."1.29Myocardial ischemia detected by thallium scintigraphy is frequently related to cardiac arrest and syncope in young patients with hypertrophic cardiomyopathy. ( Bonow, RO; Dilsizian, V; Epstein, SE; Fananapazir, L, 1993)
"The short-coupled variant of torsade de pointes should be identified because of their ECG pattern and the risk of sudden death in young adults with no structural heart disease."1.29Short-coupled variant of torsade de pointes. A new electrocardiographic entity in the spectrum of idiopathic ventricular tachyarrhythmias. ( Burguera, M; Coumel, P; Glaser, E; Leenhardt, A; Maison-Blanche, P; Nürnberg, M, 1994)
"Torsade de pointes (TdP) syncopal episodes were almost invariably precipitated by emotional stress or menstruation in a 17-year-old girl."1.28Role of early afterdepolarization in familial long QTU syndrome and torsade de pointes. ( Liu, WY; Zheng, LR; Zhou, JT, 1992)
"Calcium-channel blockers are useful for the treatment of hypertrophic cardiomyopathy (HCM), but, their adverse effects, especially, those of diltiazem, have not been of much concern."1.27Adverse effects of atrial fibrillation and syncope induced by calcium-channel blockers in hypertrophic cardiomyopathy. ( Doiuchi, J; Hamada, M; Ito, T; Kokubu, T; Ochi, T, 1985)
"Verapamil's effects were studied in eight patients and procainamide's effects in ten patients."1.26Contrasting effects of verapamil and procainamide on intraventricular conduction and reentry within the His-Purkinje system in man. ( McAllister, RG; Orr, CM; Reddy, CP, 1982)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19906 (33.33)18.7374
1990's8 (44.44)18.2507
2000's2 (11.11)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fagundes, A1
DE Magalhaes, LP1
Russo, M1
Xavier, E1
Carey, MG1
Pelter, MM1
Cao, P1
Pillow, MT1
Jacobs, A1
Knight, BP1
McDonald, KT1
Burke, MC1
Rosso, R1
Kalman, JM1
Rogowski, O1
Diamant, S1
Birger, A1
Biner, S1
Belhassen, B1
Viskin, S1
Canedo, MI1
Frank, MJ1
Reddy, CP1
Orr, CM1
McAllister, RG1
Ng, KS1
Wen, MS1
Yeh, SJ1
Lin, FC1
Wu, D1
Dilsizian, V1
Bonow, RO1
Epstein, SE1
Fananapazir, L1
Leenhardt, A2
Glaser, E2
Burguera, M2
Nürnberg, M2
Maison-Blanche, P2
Coumel, P2
Jhamb, DK1
Singh, B1
Sharda, B1
Kaul, U1
Goel, P1
Talwar, KK1
Wasir, HS1
Müller, U1
Jochheim, R1
Knaup, W1
Tenholt, M1
Gómez Pajuelo, C1
Gómez Sánchez, MA1
Delgado Jiménez, JF1
Tascón Pérez, JC1
Rodríguez Torras, ML1
Sáenz de la Calzada, C1
Bernuth, G1
Lang, D1
Hofstetter, R1
Zhou, JT1
Zheng, LR1
Liu, WY1
Schöls, W1
Brachmann, J1
Schmitt, C1
Waldecker, B1
Kübler, W1
Trohman, RG1
Feldman, T1
Palomo, AR1
Kessler, KM1
Myerberg, RJ1
Doiuchi, J1
Hamada, M1
Ochi, T1
Ito, T1
Kokubu, T1

Reviews

1 review available for verapamil and Syncope

ArticleYear
[An anomalous origin of the left coronary artery associated with a right coronary spasm as the cause of angina and presyncope].
    Revista espanola de cardiologia, 1999, Volume: 52, Issue:2

    Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Vasospasm; Coronary Vessel Anomalies; Dru

1999

Trials

1 trial available for verapamil and Syncope

ArticleYear
Comparative study of the efficacy of metoprolol and verapamil in patients with syncope and positive head-up tilt test response.
    American heart journal, 1996, Volume: 132, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Female; Heart

1996

Other Studies

16 other studies available for verapamil and Syncope

ArticleYear
Pharmacological treatment of electrical storm in cathecolaminergic polymorphic ventricular tachycardia.
    Pacing and clinical electrophysiology : PACE, 2010, Volume: 33, Issue:3

    Topics: Adolescent; Anti-Arrhythmia Agents; Atenolol; Defibrillators, Implantable; Drug Therapy, Combination

2010
Pharmacological cardiosuppression.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2010, Volume: 19, Issue:5

    Topics: Aged, 80 and over; Calcium Channel Blockers; Electrocardiography; Female; Heart Block; Humans; Synco

2010
Verapamil decreases ventricular tachyarrhythmias in a patient with Timothy syndrome (LQT8).
    Heart rhythm, 2006, Volume: 3, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Calcium Channel Blockers; Combined Modality Therapy; Defibrillat

2006
Calcium channel blockers and beta-blockers versus beta-blockers alone for preventing exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardia.
    Heart rhythm, 2007, Volume: 4, Issue:9

    Topics: Adrenergic beta-Antagonists; Aged; Calcium Channel Blockers; Catecholamines; Child; Drug Therapy, Co

2007
Therapy of hypertrophic cardiomyopathy: medical or surgical? clinical and pathophysiologic considerations.
    The American journal of cardiology, 1981, Volume: 48, Issue:2

    Topics: Adrenergic beta-Antagonists; Calcium; Cardiomyopathy, Hypertrophic; Heart; Heart Conduction System;

1981
Contrasting effects of verapamil and procainamide on intraventricular conduction and reentry within the His-Purkinje system in man.
    Acta cardiologica, 1982, Volume: 37, Issue:4

    Topics: Adult; Aged; Bundle of His; Cardiac Pacing, Artificial; Electrophysiology; Female; Heart Block; Hear

1982
The effects of adenosine on idiopathic ventricular tachycardia.
    The American journal of cardiology, 1994, Jul-15, Volume: 74, Issue:2

    Topics: Adenosine Triphosphate; Adolescent; Adult; Bundle-Branch Block; Child; Electrocardiography; Exercise

1994
Myocardial ischemia detected by thallium scintigraphy is frequently related to cardiac arrest and syncope in young patients with hypertrophic cardiomyopathy.
    Journal of the American College of Cardiology, 1993, Volume: 22, Issue:3

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Cardiac Pacing, Artificial; Cardiomyopathy, Hypertro

1993
[Torsades de pointes with short coupling interval].
    Archives des maladies du coeur et des vaisseaux, 1993, Volume: 86, Issue:5 Suppl

    Topics: Defibrillators, Implantable; Electrocardiography; Female; Humans; Male; Syncope; Torsades de Pointes

1993
Short-coupled variant of torsade de pointes. A new electrocardiographic entity in the spectrum of idiopathic ventricular tachyarrhythmias.
    Circulation, 1994, Volume: 89, Issue:1

    Topics: Adult; Cardiac Pacing, Artificial; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardi

1994
[Implantable event recorder: a new aid for the diagnosis of arrhythmogenic syncope].
    Deutsche medizinische Wochenschrift (1946), 1998, Nov-13, Volume: 123, Issue:46

    Topics: Anti-Arrhythmia Agents; Atrial Premature Complexes; Digitalis Glycosides; Drug Eruptions; Electrocar

1998
[Exercise-induced tachyarrhythmic syncopes with sinus bradycardia and normal QT-interval at rest (author's transl)].
    Zeitschrift fur Kardiologie, 1977, Volume: 66, Issue:2

    Topics: Bradycardia; Child; Electrocardiography; Female; Humans; Male; Physical Exertion; Pindolol; Practolo

1977
Role of early afterdepolarization in familial long QTU syndrome and torsade de pointes.
    Pacing and clinical electrophysiology : PACE, 1992, Volume: 15, Issue:11 Pt 2

    Topics: Action Potentials; Adolescent; Cardiac Pacing, Artificial; Epinephrine; Female; Heart Conduction Sys

1992
[Continuous ventricular tachyarrhythmia in patients without detectable organic heart disease: clinical and electrophysiologic findings].
    Zeitschrift fur Kardiologie, 1989, Volume: 78, Issue:12

    Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Child; Electrocardiogra

1989
Verapamil, syncope, and hypertrophic obstructive cardiomyopathy.
    The New England journal of medicine, 1986, Jun-12, Volume: 314, Issue:24

    Topics: Cardiomyopathy, Hypertrophic; Constipation; Humans; Male; Middle Aged; Syncope; Verapamil

1986
Adverse effects of atrial fibrillation and syncope induced by calcium-channel blockers in hypertrophic cardiomyopathy.
    Clinical cardiology, 1985, Volume: 8, Issue:3

    Topics: Adult; Atrial Fibrillation; Benzazepines; Cardiomyopathy, Hypertrophic; Diltiazem; Echocardiography;

1985