verapamil has been researched along with Stroke in 30 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (3.33) | 18.2507 |
2000's | 15 (50.00) | 29.6817 |
2010's | 12 (40.00) | 24.3611 |
2020's | 2 (6.67) | 2.80 |
Authors | Studies |
---|---|
Anger, T | 1 |
Madge, DJ | 1 |
Mulla, M | 1 |
Riddall, D | 1 |
Redondo, M | 1 |
Zarruk, JG | 1 |
Ceballos, P | 1 |
Pérez, DI | 1 |
Pérez, C | 1 |
Perez-Castillo, A | 1 |
Moro, MA | 1 |
Brea, J | 1 |
Val, C | 1 |
Cadavid, MI | 1 |
Loza, MI | 1 |
Campillo, NE | 1 |
Martínez, A | 1 |
Gil, C | 1 |
Sava, RI | 1 |
Chen, YE | 1 |
Smith, SM | 2 |
Gong, Y | 3 |
Cooper-DeHoff, RM | 5 |
Keeley, EC | 1 |
Pepine, CJ | 9 |
Handberg, EM | 2 |
Bobenko, AI | 1 |
Heller, S | 1 |
Schmitt, N | 1 |
Cherdtrakulkiat, R | 1 |
Lawung, R | 1 |
Nabu, S | 1 |
Tantimavanich, S | 1 |
Sinthupoom, N | 1 |
Prachayasittikul, S | 1 |
Prachayasittikul, V | 1 |
Zhang, B | 1 |
Wu, C | 1 |
Zhang, Z | 2 |
Yan, K | 1 |
Li, C | 2 |
Li, Y | 5 |
Li, L | 3 |
Zheng, C | 1 |
Xiao, Y | 1 |
He, D | 1 |
Zhao, F | 1 |
Su, JF | 1 |
Lun, SM | 1 |
Hou, YJ | 1 |
Duan, LJ | 1 |
Wang, NC | 1 |
Shen, FF | 1 |
Zhang, YW | 1 |
Gao, ZW | 1 |
Li, J | 5 |
Du, XJ | 1 |
Zhou, FY | 1 |
Yin, Z | 1 |
Zhu, J | 2 |
Yan, D | 1 |
Lou, H | 1 |
Yu, H | 1 |
Feng, C | 1 |
Wang, Z | 1 |
Wang, Y | 4 |
Hu, X | 1 |
Li, Z | 2 |
Shen, Y | 1 |
Hu, D | 1 |
Chen, H | 1 |
Wu, X | 1 |
Duan, Y | 1 |
Zhi, D | 1 |
Zou, M | 2 |
Zhao, Z | 1 |
Zhang, X | 2 |
Yang, X | 2 |
Zhang, J | 2 |
Wang, H | 1 |
Popović, KJ | 1 |
Popović, DJ | 1 |
Miljković, D | 1 |
Lalošević, D | 1 |
Čapo, I | 1 |
Popović, JK | 1 |
Liu, M | 1 |
Song, H | 2 |
Xing, Z | 1 |
Lu, G | 1 |
Chen, D | 1 |
Valentini, AM | 1 |
Di Pinto, F | 1 |
Coletta, S | 1 |
Guerra, V | 1 |
Armentano, R | 1 |
Caruso, ML | 1 |
Gong, J | 1 |
Wang, N | 1 |
Bian, L | 1 |
Wang, M | 1 |
Ye, M | 1 |
Wen, N | 1 |
Fu, M | 1 |
Fan, W | 2 |
Meng, Y | 1 |
Dong, G | 1 |
Lin, XH | 1 |
Liu, HH | 1 |
Gao, DM | 1 |
Cui, JF | 1 |
Ren, ZG | 1 |
Chen, RX | 1 |
Önal, B | 1 |
Özen, D | 1 |
Demir, B | 1 |
Akkan, AG | 1 |
Özyazgan, S | 1 |
Payette, G | 1 |
Geoffroy, V | 1 |
Martineau, C | 1 |
Villemur, R | 1 |
Jameel, T | 1 |
Baig, M | 1 |
Gazzaz, ZJ | 1 |
Tashkandi, JM | 1 |
Al Alhareth, NS | 1 |
Khan, SA | 1 |
Butt, NS | 1 |
Wang, J | 2 |
Geng, Y | 1 |
Zhang, Y | 4 |
Wang, X | 2 |
Liu, J | 2 |
Basit, A | 1 |
Miao, T | 1 |
Liu, W | 1 |
Jiang, W | 1 |
Yu, ZY | 1 |
Wu, L | 2 |
Qu, B | 1 |
Sun, JX | 1 |
Cai, AL | 1 |
Xie, LM | 1 |
Groeneveld, J | 1 |
Ho, SL | 1 |
Mackensen, A | 1 |
Mohtadi, M | 1 |
Laepple, T | 1 |
Genovesi, S | 1 |
Nava, E | 1 |
Bartolucci, C | 1 |
Severi, S | 1 |
Vincenti, A | 1 |
Contaldo, G | 1 |
Bigatti, G | 1 |
Ciurlino, D | 1 |
Bertoli, SV | 1 |
Slovak, JE | 1 |
Hwang, JK | 1 |
Rivera, SM | 1 |
Villarino, NF | 1 |
Li, S | 1 |
Cao, G | 1 |
Ling, M | 1 |
Ji, J | 1 |
Zhao, D | 1 |
Sha, Y | 1 |
Gao, X | 1 |
Liang, C | 2 |
Guo, Q | 1 |
Zhou, C | 1 |
Ma, Z | 1 |
Xu, J | 1 |
Wang, C | 1 |
Zhao, W | 1 |
Xia, X | 1 |
Jiang, Y | 1 |
Peng, J | 1 |
Jia, Z | 1 |
Li, F | 1 |
Chen, X | 2 |
Mo, J | 1 |
Zhang, S | 2 |
Li, X | 2 |
Huang, T | 1 |
Zhu, Q | 1 |
Wang, S | 1 |
Ge, RS | 1 |
Fortunato, G | 1 |
Lin, J | 2 |
Agarwal, PK | 1 |
Kohen, A | 1 |
Singh, P | 1 |
Cheatum, CM | 1 |
Zhu, D | 1 |
Hayman, A | 1 |
Kebede, B | 1 |
Stewart, I | 1 |
Chen, G | 1 |
Frew, R | 1 |
Guo, X | 1 |
Gong, Q | 1 |
Borowiec, J | 1 |
Han, S | 1 |
Zhang, M | 1 |
Willis, M | 1 |
Kreouzis, T | 1 |
Yu, K | 1 |
Chirvony, VS | 1 |
Sekerbayev, KS | 1 |
Pérez-Del-Rey, D | 1 |
Martínez-Pastor, JP | 1 |
Palazon, F | 1 |
Boix, PP | 1 |
Taurbayev, TI | 1 |
Sessolo, M | 1 |
Bolink, HJ | 1 |
Lu, M | 1 |
Lan, Y | 1 |
Xiao, J | 1 |
Song, M | 1 |
Chen, C | 1 |
Huang, Q | 1 |
Cao, Y | 1 |
Ho, CT | 1 |
Qi, B | 1 |
Wang, Q | 1 |
Zhang, W | 1 |
Fang, L | 1 |
Xie, CL | 1 |
Chen, R | 1 |
Yang, S | 1 |
Xia, JM | 1 |
Zhang, GY | 1 |
Chen, CH | 1 |
Yang, XW | 1 |
Domenech-Ximenos, B | 1 |
Garza, MS | 1 |
Prat-González, S | 1 |
Sepúlveda-Martínez, Á | 1 |
Crispi, F | 1 |
Perea, RJ | 1 |
Garcia-Alvarez, A | 1 |
Sitges, M | 1 |
Kalumpha, M | 1 |
Guyo, U | 1 |
Zinyama, NP | 1 |
Vakira, FM | 1 |
Nyamunda, BC | 1 |
Varga, M | 1 |
Drácz, L | 1 |
Kolbenheyer, E | 1 |
Varga, F | 1 |
Patai, ÁV | 1 |
Solymosi, N | 1 |
Patai, Á | 1 |
Kiss, J | 1 |
Gaál, V | 1 |
Nyul, Z | 1 |
Mosdósi, B | 1 |
Valdez, M | 1 |
Moosavi, L | 1 |
Heidari, A | 1 |
Novakovic-Agopian, T | 1 |
Kornblith, E | 1 |
Abrams, G | 1 |
McQuaid, JR | 1 |
Posecion, L | 1 |
Burciaga, J | 1 |
D'Esposito, M | 1 |
Chen, AJW | 1 |
Samy El Gendy, NM | 1 |
Wesolowska, P | 1 |
Georg, D | 1 |
Lechner, W | 1 |
Kazantsev, P | 1 |
Bokulic, T | 1 |
Tedgren, AC | 1 |
Adolfsson, E | 1 |
Campos, AM | 1 |
Alves, VGL | 1 |
Suming, L | 1 |
Hao, W | 1 |
Ekendahl, D | 1 |
Koniarova, I | 1 |
Bulski, W | 1 |
Chelminski, K | 1 |
Samper, JLA | 1 |
Vinatha, SP | 1 |
Rakshit, S | 1 |
Siri, S | 1 |
Tomsejm, M | 1 |
Tenhunen, M | 1 |
Povall, J | 1 |
Kry, SF | 1 |
Followill, DS | 1 |
Thwaites, DI | 1 |
Izewska, J | 1 |
Kang, JH | 1 |
Yoon, Y | 1 |
Song, J | 1 |
Van de Winckel, A | 1 |
Gauthier, L | 1 |
Chao, CT | 1 |
Lee, YH | 1 |
Li, CM | 1 |
Han, DS | 1 |
Huang, JW | 1 |
Huang, KC | 1 |
Ni, L | 1 |
Güttinger, R | 1 |
Triana, CA | 1 |
Spingler, B | 1 |
Baldridge, KK | 1 |
Patzke, GR | 1 |
Shen, X | 1 |
Wang, B | 1 |
Xie, S | 1 |
Deng, W | 1 |
Wu, D | 1 |
Zhang, Q | 1 |
Voskamp, BJ | 1 |
Peelen, MJCS | 1 |
Ravelli, ACJ | 1 |
van der Lee, R | 1 |
Mol, BWJ | 1 |
Pajkrt, E | 1 |
Ganzevoort, W | 1 |
Kazemier, BM | 1 |
Tibrewala, R | 1 |
Bahroos, E | 1 |
Mehrabian, H | 1 |
Foreman, SC | 1 |
Link, TM | 1 |
Pedoia, V | 1 |
Majumdar, S | 1 |
Jablonski, CL | 1 |
Leonard, C | 1 |
Salo, P | 1 |
Krawetz, RJ | 1 |
Yoon, N | 1 |
Hong, SN | 1 |
Cho, JG | 1 |
Jeong, HK | 1 |
Lee, KH | 1 |
Park, HW | 1 |
Barman, S | 1 |
Konai, MM | 1 |
Samaddar, S | 1 |
Haldar, J | 1 |
Mohamed, HSH | 1 |
Li, CF | 1 |
Hu, ZY | 1 |
Deng, Z | 1 |
Chen, LH | 1 |
Su, BL | 1 |
Chu, K | 1 |
Liu, YP | 1 |
Li, YB | 1 |
Zhang, H | 1 |
Xu, C | 1 |
Zou, Z | 1 |
Wu, Z | 1 |
Xia, Y | 1 |
Zhao, P | 1 |
Wang, HT | 1 |
de Biase, S | 1 |
Pellitteri, G | 1 |
Gigli, GL | 1 |
Valente, M | 1 |
Ismael, S | 1 |
Nasoohi, S | 1 |
Yoo, A | 1 |
Mirzahosseini, G | 1 |
Ahmed, HA | 1 |
Ishrat, T | 1 |
Fraser, JF | 2 |
Maniskas, M | 1 |
Trout, A | 1 |
Lukins, D | 1 |
Parker, L | 1 |
Stafford, WL | 1 |
Alhajeri, A | 1 |
Roberts, J | 1 |
Bix, GJ | 2 |
Washam, JB | 1 |
Hellkamp, AS | 1 |
Lokhnygina, Y | 1 |
Piccini, JP | 1 |
Berkowitz, SD | 1 |
Nessel, CC | 1 |
Becker, RC | 1 |
Breithardt, G | 1 |
Fox, KAA | 1 |
Halperin, JL | 1 |
Hankey, GJ | 1 |
Mahaffey, KW | 1 |
Singer, DE | 1 |
Patel, MR | 1 |
Huang, L | 1 |
Shang, E | 1 |
Li, B | 1 |
He, S | 1 |
Fu, Y | 1 |
Fang, W | 1 |
Carr, E | 1 |
Joudeh, L | 1 |
Maniskas, ME | 1 |
Roberts, JM | 1 |
Aron, I | 1 |
Khodneva, Y | 1 |
Shalev, A | 1 |
Frank, SJ | 1 |
Carson, AP | 1 |
Safford, MM | 1 |
Lena, J | 1 |
Eskandari, R | 1 |
Infinger, L | 1 |
Fargen, KM | 1 |
Spiotta, A | 1 |
Turk, A | 1 |
Turner, RD | 1 |
Chaudry, I | 1 |
Huo, T | 1 |
Handberg, E | 2 |
Gulati, M | 1 |
Merz, CN | 1 |
Bangalore, S | 2 |
Messerli, FH | 5 |
Cohen, JD | 2 |
Bacher, PH | 1 |
Sleight, P | 2 |
Mancia, G | 4 |
Kowey, P | 1 |
Zhou, Q | 2 |
Champion, A | 4 |
Kiga, C | 1 |
Sakurai, H | 1 |
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Shimada, Y | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
INternational VErapamil SR Trandolapril STudy[NCT00133692] | Phase 4 | 22,000 participants | Interventional | 1997-09-30 | Completed | ||
A Randomised, Double-blind, Placebo Controlled, Parallel Group, Multi-centre Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of Verapamil SR on Preservation of Beta-cell Function (Ver-A-T1D)[NCT04545151] | Phase 2 | 138 participants (Anticipated) | Interventional | 2021-02-08 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
4 reviews available for verapamil and Stroke
Article | Year |
---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Mo | 2001 |
Topics: Acetylcholine; Acinetobacter baumannii; Actinobacteria; Action Potentials; Adalimumab; Adaptation, P | 2019 |
Chronopharmacology of cardiovascular therapy.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Blood Pressu | 2002 |
Protection against stroke and dementia: an update on the latest clinical trial evidence.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl | 2004 |
6 trials available for verapamil and Stroke
Article | Year |
---|---|
Intra-arterial verapamil post-thrombectomy is feasible, safe, and neuroprotective in stroke.
Topics: Adult; Aged; Aged, 80 and over; Animals; Anti-Arrhythmia Agents; Brain Ischemia; Cell Death; Cells, | 2017 |
Efficacy and Safety of Rivaroxaban Versus Warfarin in Patients Taking Nondihydropyridine Calcium Channel Blockers for Atrial Fibrillation (from the ROCKET AF Trial).
Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Calcium Channel Blockers; Diltiazem | 2017 |
Verapamil-sustained release-based treatment strategy is equivalent to atenolol-based treatment strategy at reducing cardiovascular events in patients with prior myocardial infarction: an INternational VErapamil SR-Trandolapril (INVEST) substudy.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Atenol | 2008 |
Pulse pressure and risk of cardiovascular outcomes in patients with hypertension and coronary artery disease: an INternational VErapamil SR-trandolapril STudy (INVEST) analysis.
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Coronary Artery Disease; Coronary Disease; | 2009 |
Dogma disputed: can aggressively lowering blood pressure in hypertensive patients with coronary artery disease be dangerous?
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Cause of Death; Coronary Artery Disease; Di | 2006 |
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann | 2006 |
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann | 2006 |
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann | 2006 |
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann | 2006 |
20 other studies available for verapamil and Stroke
Article | Year |
---|---|
Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model.
Topics: Animals; Blood-Brain Barrier; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 7; Disease | 2012 |
Risk and Blood Pressure Control Rates Across the Spectrum of Coronary Artery Disease in Hypertensive Women: An Analysis from The INternational VErapamil SR-Trandolapril STudy (INVEST).
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Cha | 2020 |
Verapamil as an Adjunct Therapy to Reduce tPA Toxicity in Hyperglycemic Stroke: Implication of TXNIP/NLRP3 Inflammasome.
Topics: Animals; Carrier Proteins; Drug Therapy, Combination; Fibrinolytic Agents; Hyperglycemia; Male; Mice | 2021 |
S-oxiracetam protect against ischemic stroke via alleviating blood brain barrier dysfunction in rats.
Topics: Animals; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cla | 2017 |
A Young Woman With A History of Stroke and Recurrent Migraine Headaches.
Topics: Adult; Anti-Arrhythmia Agents; Biopsy; CADASIL; Female; Humans; Magnetic Resonance Imaging; Migraine | 2019 |
Stroke neuroprotection revisited: Intra-arterial verapamil is profoundly neuroprotective in experimental acute ischemic stroke.
Topics: Acute Disease; Animals; Apoptosis; Behavior, Animal; Brain Ischemia; Calcium Channel Blockers; Cell | 2016 |
Calcium channel blocker use is associated with lower fasting serum glucose among adults with diabetes from the REGARDS study.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Calcium Channel Blockers; Diabetes Mellitus; Dose-Response R | 2016 |
Basilar artery occlusion in a child treated successfully with mechanical thrombectomy using ADAPT.
Topics: Arterial Occlusive Diseases; Basilar Artery; Cerebral Angiography; Child; Combined Modality Therapy; | 2016 |
Mortality Risk Associated With Resistant Hypertension Among Women: Analysis from Three Prospective Cohorts Encompassing the Spectrum of Women's Heart Disease.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Artery Disease; Drug Resistance; Fema | 2016 |
Proteomic identification of haptoglobin as a stroke plasma biomarker in spontaneously hypertensive stroke-prone rats.
Topics: Animals; Biomarkers; Blood Proteins; Haptoglobins; Hypertension; Male; Proteomics; Rats; Rats, Inbre | 2008 |
Overlapping features of eclampsia and postpartum angiopathy.
Topics: Adult; Cerebrovascular Disorders; Eclampsia; Female; Headache; Humans; Methylprednisolone; Nicardipi | 2009 |
Recurrent stroke due to a novel voltage sensor mutation in Cav2.1 responds to verapamil.
Topics: Calcium Channels; Calcium Channels, N-Type; Child; Female; Humans; Mutation; Secondary Prevention; S | 2011 |
Harmful effects of NSAIDs among patients with hypertension and coronary artery disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Celec | 2011 |
Cerebral vasoconstriction and stroke after use of serotonergic drugs.
Topics: Cerebrovascular Circulation; Humans; Migraine Disorders; Serotonin Agents; Stroke; Vasoconstriction; | 2002 |
VISP and INVEST.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; | 2004 |
[Stroke and other thromboembolic complications of atrial fibrillation. Part v. The use of drugs without antithrombotic or antiarrhythmic properties.].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Humans; Stroke; Verapamil | 2004 |
Adult hypertension: reducing cardiovascular morbidity and mortality.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Alcohol Drinking | 2005 |
Predictors of adverse outcome among patients with hypertension and coronary artery disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Calcium | 2006 |
Predicting stroke risk in hypertensive patients with coronary artery disease: a report from the INVEST.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Atenolol; Black People; Coronary Artery Disease; D | 2008 |
Stroke-prone spontaneously hypertensive rats lose their ability to auto-regulate cerebral blood flow prior to stroke.
Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Diet; Homeostasis; Hypertension; In Vitro Tech | 1999 |