verapamil has been researched along with Stomach Neoplasms in 21 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Stomach Neoplasms: Tumors or cancer of the STOMACH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To establish a simple method for estimating residual peritoneal ascites in order to determine the optimum verapamil (VRP) initial concentration in the intraperitoneal perfusion chemotherapy." | 7.80 | Studies on assessment methods of malignant ascites residue and changes of verapamil concentration in intraperitoneal perfusion chemotherapy. ( Duan, Q; Fan, P; Jia, W; Liu, Y; Ma, K; Wen, C; Wu, Y; Zhang, T, 2014) |
| "The purpose of this study was to assess the efficacy of verapamil (20 microM) and hyperthermia (42 degrees C) as modifiers of 5-fluorouracil (5-FU), used at different concentrations, in inhibiting the growth of gastric adenocarcinoma cells." | 7.69 | Antitumour activity of 5-fluorouracil, verapamil and hyperthermia against human gastric adenocarcinoma cell (AGS) in vitro. ( Brenner, RV; Buras, RR; Evans, SR; Nauta, RJ; Shabahang, M; Shchepotin, IB, 1994) |
| "The purpose of this study was to assess the efficacy of verapamil (20 microM) and hyperthermia (42 degrees C) as modifiers of mitomycin C (MMC), used at different concentrations, in inhibiting the growth of human gastric adenocarcinoma (AGS) cells." | 7.69 | Effect of mitomycin C, verapamil, and hyperthermia on human gastric adenocarcinoma. ( Buras, RR; Evans, SR; Nauta, RJ; Shabahang, M; Shchepotin, IB, 1994) |
| "To establish a simple method for estimating residual peritoneal ascites in order to determine the optimum verapamil (VRP) initial concentration in the intraperitoneal perfusion chemotherapy." | 3.80 | Studies on assessment methods of malignant ascites residue and changes of verapamil concentration in intraperitoneal perfusion chemotherapy. ( Duan, Q; Fan, P; Jia, W; Liu, Y; Ma, K; Wen, C; Wu, Y; Zhang, T, 2014) |
| "The purpose of this study was to assess the efficacy of verapamil (20 microM) and hyperthermia (42 degrees C) as modifiers of 5-fluorouracil (5-FU), used at different concentrations, in inhibiting the growth of gastric adenocarcinoma cells." | 3.69 | Antitumour activity of 5-fluorouracil, verapamil and hyperthermia against human gastric adenocarcinoma cell (AGS) in vitro. ( Brenner, RV; Buras, RR; Evans, SR; Nauta, RJ; Shabahang, M; Shchepotin, IB, 1994) |
| "The purpose of this study was to assess the efficacy of verapamil (20 microM) and hyperthermia (42 degrees C) as modifiers of mitomycin C (MMC), used at different concentrations, in inhibiting the growth of human gastric adenocarcinoma (AGS) cells." | 3.69 | Effect of mitomycin C, verapamil, and hyperthermia on human gastric adenocarcinoma. ( Buras, RR; Evans, SR; Nauta, RJ; Shabahang, M; Shchepotin, IB, 1994) |
| "Recombinant human-interferon-gamma (rH-IFN-gamma) and verapamil (VRP), either alone or in combination, were evaluated in MTT assay for their modification effects on adriamycin-induced cytotoxicity against MKN-45, human stomach adenocarcinoma cells." | 3.68 | Modification of adriamycin-induced cytotoxicity by recombinant human interferon-gamma and/or verapamil in human stomach cancer cells. ( Hong, WS; Kang, TW; Kim, CM; Lee, CT; Lee, JO, 1992) |
| "The present study evaluated the efficacy of chemotherapy combined with targeted arterial infusion of verapamil in patients with advanced gastric cancer." | 2.79 | Efficacy of chemotherapy combined with targeted arterial infusion of verapamil in patients with advanced gastric cancer. ( Chen, D; Duan, Q; Fan, G; Fan, P; Liu, A; Ning, Z; Zhang, T, 2014) |
| "Gastric carcinoma is one of the most common malignant tumors and one of the most common cancer-related fatal diseases." | 1.56 | Effect of verapamil in the reversal of doxorubicin chemotherapy resistance in advanced gastric cancer. ( Fan, GF; Fan, PS; Li, Y; Sun, B; Wang, X; Zhang, TY, 2020) |
| "We analyzed the clinical observations of target arterial infusion of verapamil combined with chemotherapy as therapy for advanced gastric cancer." | 1.48 | The clinical observation of verapamil in combination with interventional chemotherapy in advanced gastric cancer. ( Dai, HB; Duan, QH; Fan, GF; Fan, PS; Huang, J; Liu, M; Liu, YB; Pan, JJ; Tang, LL; Weng, CT; Wu, Y; Yang, GH; Zhang, TY; Zhu, ZQ, 2018) |
| "Arsenic trioxide has been used as a therapeutic agent for acute promyelocytic leukemia and recently for some solid tumors." | 1.35 | The overexpression of multidrug resistance-associated proteins and gankyrin contribute to arsenic trioxide resistance in liver and gastric cancer cells. ( Chen, X; Liu, LX; Zhang, M, 2009) |
| "The expression of MRP gene in gastric cancer cell lines varied from a low to a high level, but mdrl was not detected in any of these cell lines." | 1.29 | The multidrug resistance-associated protein gene confers drug resistance in human gastric and colon cancers. ( Cowan, KH; Fukuda, M; Ikeda, K; Kohno, S; Matsuo, I; Nakano, R; Narasaki, F; Oka, M; Soda, H; Takatani, H; Terashi, K; Tomonaga, M, 1996) |
| "Its internalization in human gastric cancer cell line SGC-7901 was followed by double dynamic EM labelling procedure using streptavidin-gold and sheep anti-mouse IgG-gold probes." | 1.28 | [Immuno-ricin A chain specific for gastric cancer: internalization and its significance]. ( Wang, F, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 8 (38.10) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, YC | 1 |
| Jin, LF | 1 |
| Ren, HM | 1 |
| Zhang, SJ | 1 |
| Liu, YJ | 1 |
| Xu, YT | 1 |
| He, ZH | 1 |
| Song, Y | 1 |
| Yuan, H | 1 |
| Chen, SH | 1 |
| Guan, YY | 1 |
| Wang, X | 1 |
| Li, Y | 1 |
| Fan, GF | 2 |
| Zhang, TY | 2 |
| Sun, B | 1 |
| Fan, PS | 2 |
| Shiozaki, A | 1 |
| Katsurahara, K | 1 |
| Kudou, M | 1 |
| Shimizu, H | 1 |
| Kosuga, T | 1 |
| Ito, H | 1 |
| Arita, T | 1 |
| Konishi, H | 1 |
| Komatsu, S | 1 |
| Kubota, T | 1 |
| Fujiwara, H | 1 |
| Okamoto, K | 1 |
| Otsuji, E | 1 |
| Pan, JJ | 1 |
| Liu, YB | 1 |
| Huang, J | 1 |
| Weng, CT | 1 |
| Liu, M | 1 |
| Duan, QH | 1 |
| Wu, Y | 2 |
| Tang, LL | 1 |
| Yang, GH | 1 |
| Dai, HB | 1 |
| Zhu, ZQ | 1 |
| Ning, Z | 1 |
| Chen, D | 1 |
| Liu, A | 1 |
| Fan, P | 2 |
| Duan, Q | 2 |
| Zhang, T | 2 |
| Fan, G | 1 |
| Wen, C | 1 |
| Liu, Y | 1 |
| Ma, K | 1 |
| Jia, W | 1 |
| Li, X | 1 |
| Zhang, Y | 2 |
| Xiong, C | 1 |
| Jin, H | 2 |
| Jing, B | 1 |
| Fan, D | 3 |
| Chen, X | 1 |
| Zhang, M | 1 |
| Liu, LX | 1 |
| Du, J | 1 |
| Pan, Y | 1 |
| Shi, Y | 1 |
| Guo, C | 1 |
| Jin, X | 1 |
| Sun, L | 1 |
| Liu, N | 1 |
| Qiao, T | 1 |
| Wang, J | 2 |
| Xia, Y | 1 |
| Wang, H | 1 |
| Hou, Z | 1 |
| Hong, L | 1 |
| Zhao, Y | 1 |
| Han, Z | 1 |
| Zhou, X | 1 |
| Guo, W | 1 |
| Zhang, X | 1 |
| Wu, K | 1 |
| Ding, J | 1 |
| Nozue, M | 1 |
| Nishida, M | 1 |
| Todoroki, T | 1 |
| Fukao, K | 1 |
| Tanaka, M | 1 |
| Shchepotin, IB | 2 |
| Shabahang, M | 2 |
| Nauta, RJ | 2 |
| Buras, RR | 2 |
| Brenner, RV | 1 |
| Evans, SR | 2 |
| Tomonaga, M | 1 |
| Oka, M | 1 |
| Narasaki, F | 1 |
| Fukuda, M | 1 |
| Nakano, R | 1 |
| Takatani, H | 1 |
| Ikeda, K | 1 |
| Terashi, K | 1 |
| Matsuo, I | 1 |
| Soda, H | 1 |
| Cowan, KH | 1 |
| Kohno, S | 1 |
| Kokoska, ER | 1 |
| Smith, GS | 1 |
| Wolff, AB | 1 |
| Deshpande, Y | 1 |
| Rieckenberg, CL | 1 |
| Banan, A | 1 |
| Miller, TA | 1 |
| Stein, U | 1 |
| Lage, H | 1 |
| Jordan, A | 1 |
| Walther, W | 1 |
| Bates, SE | 1 |
| Litman, T | 1 |
| Hohenberger, P | 1 |
| Dietel, M | 1 |
| Hong, WS | 1 |
| Kim, CM | 1 |
| Lee, CT | 1 |
| Lee, JO | 1 |
| Kang, TW | 1 |
| Wang, F | 1 |
| Tatsuta, M | 1 |
| Iishi, H | 1 |
| Baba, M | 1 |
| Nakaizumi, A | 1 |
| Uehara, H | 1 |
| Taniguchi, H | 1 |
| Nakano, GI | 1 |
| Katoh, H | 1 |
| Ikeda, H | 1 |
| Sakamoto, K | 1 |
| Nagamachi, Y | 1 |
1 trial available for verapamil and Stomach Neoplasms
| Article | Year |
|---|---|
Efficacy of chemotherapy combined with targeted arterial infusion of verapamil in patients with advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Agents; Disease Progression; Drug Therapy, Combination; Female; Humans; | 2014 |
20 other studies available for verapamil and Stomach Neoplasms
| Article | Year |
|---|---|
Design, synthesis, and biological evaluation of novel dual inhibitors targeting lysine specific demethylase 1 (LSD1) and histone deacetylases (HDAC) for treatment of gastric cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Dose-Response Relationship, Drug; Dru | 2021 |
Effect of verapamil in the reversal of doxorubicin chemotherapy resistance in advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Carcin | 2020 |
Amlodipine and Verapamil, Voltage-Gated Ca
Topics: Amlodipine; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Hy | 2021 |
The clinical observation of verapamil in combination with interventional chemotherapy in advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Calcium Channel Blockers; Female; Follo | 2018 |
Studies on assessment methods of malignant ascites residue and changes of verapamil concentration in intraperitoneal perfusion chemotherapy.
Topics: Aged; Ascites; Chromatography, Liquid; Colonic Neoplasms; Female; Humans; Infusions, Parenteral; Mal | 2014 |
Overexpression of a new gene P28GANK confers multidrug resistance of gastric cancer cells.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, | 2009 |
The overexpression of multidrug resistance-associated proteins and gankyrin contribute to arsenic trioxide resistance in liver and gastric cancer cells.
Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; ATP Binding Cassette Transporter, Subfamily B; | 2009 |
Overexpression and significance of prion protein in gastric cancer and multidrug-resistant gastric carcinoma cell line SGC7901/ADR.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Apoptosis; Calcium Channel Blockers; Doxorubicin; Drug | 2005 |
Chinese herbs of Shenghe Powder reverse multidrug resistance of gastric carcinoma SGC-7901.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; | 2007 |
DARPP-32 mediates multidrug resistance of gastric cancer through regulation of P-gp and ZNRD1.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; DNA-Binding Prot | 2007 |
Selection of three out of 24 anti-cancer agents in poorly-differentiated gastric cancer cell lines, evaluated by the AUC/delta IC50 ratio.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Gene | 1995 |
Antitumour activity of 5-fluorouracil, verapamil and hyperthermia against human gastric adenocarcinoma cell (AGS) in vitro.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Combined Modality Therap | 1994 |
Effect of mitomycin C, verapamil, and hyperthermia on human gastric adenocarcinoma.
Topics: Adenocarcinoma; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Hyperthermia, | 1994 |
The multidrug resistance-associated protein gene confers drug resistance in human gastric and colon cancers.
Topics: Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; Doxorubicin; Etoposide; Genes, MD | 1996 |
Role of calcium in adaptive cytoprotection and cell injury induced by deoxycholate in human gastric cells.
Topics: Acclimatization; Calcium; Cell Membrane; Cell Survival; Deoxycholic Acid; Dose-Response Relationship | 1998 |
Impact of BCRP/MXR, MRP1 and MDR1/P-Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, M | 2002 |
Modification of adriamycin-induced cytotoxicity by recombinant human interferon-gamma and/or verapamil in human stomach cancer cells.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Doxorubicin; Drug Int | 1992 |
[Immuno-ricin A chain specific for gastric cancer: internalization and its significance].
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Endocytosis; Humans; Immunotoxins; Mice; Rici | 1992 |
Effect of calcium channel blockers on gastric carcinogenesis and caerulein enhancement of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Topics: Adenocarcinoma; Animals; Calcium Channel Blockers; Ceruletide; DNA; Gastric Juice; Gastrins; Hydroge | 1990 |
[Experimental study on combination chemotherapy of UFT and calcium antagonist in gastric cancer].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; DNA, Neoplasm; Drug Screening Assays, Antit | 1989 |