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verapamil and Shock

verapamil has been researched along with Shock in 15 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.

Research Excerpts

ExcerptRelevanceReference
" Based on the results of intravascular ultrasound the occlusion was suspected to be caused by coronary vasospasm, which was not relieved by intracoronary injection of isosorbide dinitrate (1 mg), but was alleviated by nicorandil (2 mg), a potassium-channel opener."7.74Intracoronary nicorandil relieves multiple coronary vasospasm with hemodynamic collapse. ( Hayashi, T; Ichikawa, M; Iwata, A; Lim, YJ; Mishima, M; Nakata, T, 2008)
"In an animal model of verapamil-induced shock, endogenous AVP levels increased nearly 40-fold compared with baseline levels."7.72Use of vasopressin in a canine model of severe verapamil poisoning: a preliminary descriptive study. ( Bond, GR; Johnson, SB; Sztajnkrycer, MD; Weaver, AL, 2004)
"Splanchnic artery occlusion (SAO) shock made by clamping splanchnic arteries for 45 min was performed in female rats infused for 30 min with vehicle, nimodipine, and verapamil before, during, or after SAO."7.67Splanchnic artery occlusion shock in the rat: effects of the calcium entry blockers nimodipine and verapamil. ( Altavilla, D; Berlinghieri, MC; Caputi, AP; Squadrito, F; Sturniolo, R, 1988)
"Verapamil was injected intravenously 30 min before the beginning of haemorrhage."5.28[Effects of verapamil on the activity of Ca2+, Mg2+-dependent endonucleases in the nuclei of the dog liver during prolonged hypovolemic shock]. ( Kozhura, VL; Novoderzhkina, IS; Smirnova, NV, 1991)
" Based on the results of intravascular ultrasound the occlusion was suspected to be caused by coronary vasospasm, which was not relieved by intracoronary injection of isosorbide dinitrate (1 mg), but was alleviated by nicorandil (2 mg), a potassium-channel opener."3.74Intracoronary nicorandil relieves multiple coronary vasospasm with hemodynamic collapse. ( Hayashi, T; Ichikawa, M; Iwata, A; Lim, YJ; Mishima, M; Nakata, T, 2008)
"In an animal model of verapamil-induced shock, endogenous AVP levels increased nearly 40-fold compared with baseline levels."3.72Use of vasopressin in a canine model of severe verapamil poisoning: a preliminary descriptive study. ( Bond, GR; Johnson, SB; Sztajnkrycer, MD; Weaver, AL, 2004)
"Splanchnic artery occlusion (SAO) shock made by clamping splanchnic arteries for 45 min was performed in female rats infused for 30 min with vehicle, nimodipine, and verapamil before, during, or after SAO."3.67Splanchnic artery occlusion shock in the rat: effects of the calcium entry blockers nimodipine and verapamil. ( Altavilla, D; Berlinghieri, MC; Caputi, AP; Squadrito, F; Sturniolo, R, 1988)
"A four-month-old infant with myocarditis and supraventricular tachycardia was given intravenous verapamil (0."3.67An infant fatality following verapamil therapy for supraventricular tachycardia: cardiovascular collapse following intravenous verapamil. ( Berens, RJ; Garland, JS; Losek, JD; Wilson, AD, 1985)
"Cardiogenic shock is associated with primary myocardial failure and a low-flow state."2.36Calcium entry blockers: potential applications in shock. ( Greenfield, LJ; Hess, ML, 1983)
" IFE therapy is being recommended by US PCCs; protocols and dosing regimens are nearly uniform."1.39Lipid rescue 911: Are poison centers recommending intravenous fat emulsion therapy for severe poisoning? ( Christian, MR; Mycyk, MB; Pallasch, EM; Wahl, M, 2013)
"Verapamil was injected intravenously 30 min before the beginning of haemorrhage."1.28[Effects of verapamil on the activity of Ca2+, Mg2+-dependent endonucleases in the nuclei of the dog liver during prolonged hypovolemic shock]. ( Kozhura, VL; Novoderzhkina, IS; Smirnova, NV, 1991)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's3 (20.00)18.2507
2000's4 (26.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christian, MR1
Pallasch, EM1
Wahl, M1
Mycyk, MB1
Varpula, T1
Rapola, J1
Sallisalmi, M1
Kurola, J1
Richard, AL1
Hantson, P1
Sztajnkrycer, MD1
Bond, GR1
Johnson, SB1
Weaver, AL1
Hayashi, T1
Ichikawa, M1
Iwata, A1
Nakata, T1
Lim, YJ1
Mishima, M1
Hess, ML2
Mahany, TM1
Greenfield, LJ2
Marsocci, G1
Boschetti, C1
Manai, L1
Sica, G1
Loscudo, L1
Shahar, E1
Lotan, D1
Barzilay, Z1
Lapostolle, F1
Bourdain, F1
Adnet, F1
Benaissa, A1
Muszynski, J1
Baud, F1
Kozhura, VL1
Smirnova, NV1
Novoderzhkina, IS1
Dong, BN1
Wang, YT1
Liu, ZM1
Sturniolo, R1
Altavilla, D1
Berlinghieri, MC1
Squadrito, F1
Caputi, AP1
Garland, JS1
Berens, RJ1
Losek, JD1
Wilson, AD1

Reviews

2 reviews available for verapamil and Shock

ArticleYear
Calcium channel blockers in shock.
    Progress in clinical and biological research, 1983, Volume: 111

    Topics: Calcium Channel Blockers; Cardiovascular System; Hemodynamics; Humans; Ischemia; Shock; Shock, Hemor

1983
Calcium entry blockers: potential applications in shock.
    Advances in shock research, 1983, Volume: 10

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Diltiazem; Dogs

1983

Other Studies

13 other studies available for verapamil and Shock

ArticleYear
Lipid rescue 911: Are poison centers recommending intravenous fat emulsion therapy for severe poisoning?
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2013, Volume: 9, Issue:3

    Topics: Acute Disease; Adult; Amitriptyline; Bupivacaine; Drug Overdose; Fat Emulsions, Intravenous; Guideli

2013
Treatment of serious calcium channel blocker overdose with levosimendan, a calcium sensitizer.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:3

    Topics: Acidosis, Lactic; Amlodipine; Calcium Channel Blockers; Cardiotonic Agents; Coma; Drug Overdose; Ech

2009
Cardiocirculatory collapse after a single dose of sustained-release verapamil in a cirrhotic patient: usefulness of hyperinsulinaemia-euglycaemia therapy.
    Anaesthesia and intensive care, 2010, Volume: 38, Issue:2

    Topics: Calcium Channel Blockers; Delayed-Action Preparations; Humans; Insulin; Liver Cirrhosis; Male; Shock

2010
Use of vasopressin in a canine model of severe verapamil poisoning: a preliminary descriptive study.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2004, Volume: 11, Issue:12

    Topics: Animals; Arginine Vasopressin; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Dog

2004
Intracoronary nicorandil relieves multiple coronary vasospasm with hemodynamic collapse.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:2

    Topics: Coronary Vasospasm; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Middle Aged; Nicorandil; Sho

2008
[Myocardial damage caused by ischemia and/or re-perfusion in cardiac surgery: prevention and treatment with verapamil].
    Bollettino della Societa italiana di cardiologia, 1981, Volume: 26, Issue:12

    Topics: Adult; Cardiac Output, Low; Cardiac Surgical Procedures; Coronary Artery Bypass; Coronary Disease; F

1981
Dopamine-induced paroxysmal supraventricular tachycardia in an infant.
    Clinical pediatrics, 1981, Volume: 20, Issue:8

    Topics: Dopamine; Dose-Response Relationship, Drug; Female; Humans; Infant; Shock; Tachycardia, Paroxysmal;

1981
[Acute verapamil poisoning. A proposal of a strategy for therapeutic management].
    Annales francaises d'anesthesie et de reanimation, 2000, Volume: 19, Issue:8

    Topics: Acute Disease; Adrenergic beta-Agonists; Aged; Atropine; Calcium Channel Blockers; Cardiotonic Agent

2000
[Effects of verapamil on the activity of Ca2+, Mg2+-dependent endonucleases in the nuclei of the dog liver during prolonged hypovolemic shock].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 112, Issue:12

    Topics: Animals; Cell Nucleus; Dogs; Endodeoxyribonucleases; Female; Liver; Male; Shock; Time Factors; Verap

1991
[The effects of verapamil on calcium and magnesium concentrations during intestinal shock in rats].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1991, Volume: 29, Issue:5

    Topics: Animals; Calcium; Magnesium; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains; Shock; Verapamil

1991
Morphometric study of neuromuscular junction in rabbits subjected to shock by superior mesenteric artery occlusion.
    Critical care medicine, 1990, Volume: 18, Issue:2

    Topics: Acetylcholinesterase; Adenosine Triphosphate; Animals; Liver; Mesenteric Arteries; Mesenteric Vascul

1990
Splanchnic artery occlusion shock in the rat: effects of the calcium entry blockers nimodipine and verapamil.
    Circulatory shock, 1988, Volume: 24, Issue:1

    Topics: Animals; Arterial Occlusive Diseases; Female; Leukocyte Count; Leukocytes; Nimodipine; Phagocytosis;

1988
An infant fatality following verapamil therapy for supraventricular tachycardia: cardiovascular collapse following intravenous verapamil.
    Pediatric emergency care, 1985, Volume: 1, Issue:4

    Topics: Humans; Infant; Male; Myocarditis; Shock; Tachycardia, Supraventricular; Verapamil

1985