verapamil and Shock
verapamil has been researched along with Shock in 15 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Based on the results of intravascular ultrasound the occlusion was suspected to be caused by coronary vasospasm, which was not relieved by intracoronary injection of isosorbide dinitrate (1 mg), but was alleviated by nicorandil (2 mg), a potassium-channel opener." | 7.74 | Intracoronary nicorandil relieves multiple coronary vasospasm with hemodynamic collapse. ( Hayashi, T; Ichikawa, M; Iwata, A; Lim, YJ; Mishima, M; Nakata, T, 2008) |
| "In an animal model of verapamil-induced shock, endogenous AVP levels increased nearly 40-fold compared with baseline levels." | 7.72 | Use of vasopressin in a canine model of severe verapamil poisoning: a preliminary descriptive study. ( Bond, GR; Johnson, SB; Sztajnkrycer, MD; Weaver, AL, 2004) |
| "Splanchnic artery occlusion (SAO) shock made by clamping splanchnic arteries for 45 min was performed in female rats infused for 30 min with vehicle, nimodipine, and verapamil before, during, or after SAO." | 7.67 | Splanchnic artery occlusion shock in the rat: effects of the calcium entry blockers nimodipine and verapamil. ( Altavilla, D; Berlinghieri, MC; Caputi, AP; Squadrito, F; Sturniolo, R, 1988) |
| "Verapamil was injected intravenously 30 min before the beginning of haemorrhage." | 5.28 | [Effects of verapamil on the activity of Ca2+, Mg2+-dependent endonucleases in the nuclei of the dog liver during prolonged hypovolemic shock]. ( Kozhura, VL; Novoderzhkina, IS; Smirnova, NV, 1991) |
| " Based on the results of intravascular ultrasound the occlusion was suspected to be caused by coronary vasospasm, which was not relieved by intracoronary injection of isosorbide dinitrate (1 mg), but was alleviated by nicorandil (2 mg), a potassium-channel opener." | 3.74 | Intracoronary nicorandil relieves multiple coronary vasospasm with hemodynamic collapse. ( Hayashi, T; Ichikawa, M; Iwata, A; Lim, YJ; Mishima, M; Nakata, T, 2008) |
| "In an animal model of verapamil-induced shock, endogenous AVP levels increased nearly 40-fold compared with baseline levels." | 3.72 | Use of vasopressin in a canine model of severe verapamil poisoning: a preliminary descriptive study. ( Bond, GR; Johnson, SB; Sztajnkrycer, MD; Weaver, AL, 2004) |
| "Splanchnic artery occlusion (SAO) shock made by clamping splanchnic arteries for 45 min was performed in female rats infused for 30 min with vehicle, nimodipine, and verapamil before, during, or after SAO." | 3.67 | Splanchnic artery occlusion shock in the rat: effects of the calcium entry blockers nimodipine and verapamil. ( Altavilla, D; Berlinghieri, MC; Caputi, AP; Squadrito, F; Sturniolo, R, 1988) |
| "A four-month-old infant with myocarditis and supraventricular tachycardia was given intravenous verapamil (0." | 3.67 | An infant fatality following verapamil therapy for supraventricular tachycardia: cardiovascular collapse following intravenous verapamil. ( Berens, RJ; Garland, JS; Losek, JD; Wilson, AD, 1985) |
| "Cardiogenic shock is associated with primary myocardial failure and a low-flow state." | 2.36 | Calcium entry blockers: potential applications in shock. ( Greenfield, LJ; Hess, ML, 1983) |
| " IFE therapy is being recommended by US PCCs; protocols and dosing regimens are nearly uniform." | 1.39 | Lipid rescue 911: Are poison centers recommending intravenous fat emulsion therapy for severe poisoning? ( Christian, MR; Mycyk, MB; Pallasch, EM; Wahl, M, 2013) |
| "Verapamil was injected intravenously 30 min before the beginning of haemorrhage." | 1.28 | [Effects of verapamil on the activity of Ca2+, Mg2+-dependent endonucleases in the nuclei of the dog liver during prolonged hypovolemic shock]. ( Kozhura, VL; Novoderzhkina, IS; Smirnova, NV, 1991) |
Research
Studies (15)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (40.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Christian, MR | 1 |
| Pallasch, EM | 1 |
| Wahl, M | 1 |
| Mycyk, MB | 1 |
| Varpula, T | 1 |
| Rapola, J | 1 |
| Sallisalmi, M | 1 |
| Kurola, J | 1 |
| Richard, AL | 1 |
| Hantson, P | 1 |
| Sztajnkrycer, MD | 1 |
| Bond, GR | 1 |
| Johnson, SB | 1 |
| Weaver, AL | 1 |
| Hayashi, T | 1 |
| Ichikawa, M | 1 |
| Iwata, A | 1 |
| Nakata, T | 1 |
| Lim, YJ | 1 |
| Mishima, M | 1 |
| Hess, ML | 2 |
| Mahany, TM | 1 |
| Greenfield, LJ | 2 |
| Marsocci, G | 1 |
| Boschetti, C | 1 |
| Manai, L | 1 |
| Sica, G | 1 |
| Loscudo, L | 1 |
| Shahar, E | 1 |
| Lotan, D | 1 |
| Barzilay, Z | 1 |
| Lapostolle, F | 1 |
| Bourdain, F | 1 |
| Adnet, F | 1 |
| Benaissa, A | 1 |
| Muszynski, J | 1 |
| Baud, F | 1 |
| Kozhura, VL | 1 |
| Smirnova, NV | 1 |
| Novoderzhkina, IS | 1 |
| Dong, BN | 1 |
| Wang, YT | 1 |
| Liu, ZM | 1 |
| Sturniolo, R | 1 |
| Altavilla, D | 1 |
| Berlinghieri, MC | 1 |
| Squadrito, F | 1 |
| Caputi, AP | 1 |
| Garland, JS | 1 |
| Berens, RJ | 1 |
| Losek, JD | 1 |
| Wilson, AD | 1 |
Reviews
2 reviews available for verapamil and Shock
| Article | Year |
|---|---|
Calcium channel blockers in shock.
Topics: Calcium Channel Blockers; Cardiovascular System; Hemodynamics; Humans; Ischemia; Shock; Shock, Hemor | 1983 |
Calcium entry blockers: potential applications in shock.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Diltiazem; Dogs | 1983 |
Other Studies
13 other studies available for verapamil and Shock
| Article | Year |
|---|---|
Lipid rescue 911: Are poison centers recommending intravenous fat emulsion therapy for severe poisoning?
Topics: Acute Disease; Adult; Amitriptyline; Bupivacaine; Drug Overdose; Fat Emulsions, Intravenous; Guideli | 2013 |
Treatment of serious calcium channel blocker overdose with levosimendan, a calcium sensitizer.
Topics: Acidosis, Lactic; Amlodipine; Calcium Channel Blockers; Cardiotonic Agents; Coma; Drug Overdose; Ech | 2009 |
Cardiocirculatory collapse after a single dose of sustained-release verapamil in a cirrhotic patient: usefulness of hyperinsulinaemia-euglycaemia therapy.
Topics: Calcium Channel Blockers; Delayed-Action Preparations; Humans; Insulin; Liver Cirrhosis; Male; Shock | 2010 |
Use of vasopressin in a canine model of severe verapamil poisoning: a preliminary descriptive study.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Dog | 2004 |
Intracoronary nicorandil relieves multiple coronary vasospasm with hemodynamic collapse.
Topics: Coronary Vasospasm; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Middle Aged; Nicorandil; Sho | 2008 |
[Myocardial damage caused by ischemia and/or re-perfusion in cardiac surgery: prevention and treatment with verapamil].
Topics: Adult; Cardiac Output, Low; Cardiac Surgical Procedures; Coronary Artery Bypass; Coronary Disease; F | 1981 |
Dopamine-induced paroxysmal supraventricular tachycardia in an infant.
Topics: Dopamine; Dose-Response Relationship, Drug; Female; Humans; Infant; Shock; Tachycardia, Paroxysmal; | 1981 |
[Acute verapamil poisoning. A proposal of a strategy for therapeutic management].
Topics: Acute Disease; Adrenergic beta-Agonists; Aged; Atropine; Calcium Channel Blockers; Cardiotonic Agent | 2000 |
[Effects of verapamil on the activity of Ca2+, Mg2+-dependent endonucleases in the nuclei of the dog liver during prolonged hypovolemic shock].
Topics: Animals; Cell Nucleus; Dogs; Endodeoxyribonucleases; Female; Liver; Male; Shock; Time Factors; Verap | 1991 |
[The effects of verapamil on calcium and magnesium concentrations during intestinal shock in rats].
Topics: Animals; Calcium; Magnesium; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains; Shock; Verapamil | 1991 |
Morphometric study of neuromuscular junction in rabbits subjected to shock by superior mesenteric artery occlusion.
Topics: Acetylcholinesterase; Adenosine Triphosphate; Animals; Liver; Mesenteric Arteries; Mesenteric Vascul | 1990 |
Splanchnic artery occlusion shock in the rat: effects of the calcium entry blockers nimodipine and verapamil.
Topics: Animals; Arterial Occlusive Diseases; Female; Leukocyte Count; Leukocytes; Nimodipine; Phagocytosis; | 1988 |
An infant fatality following verapamil therapy for supraventricular tachycardia: cardiovascular collapse following intravenous verapamil.
Topics: Humans; Infant; Male; Myocarditis; Shock; Tachycardia, Supraventricular; Verapamil | 1985 |