verapamil has been researched along with Sarcoma 180 in 7 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Sarcoma 180: An experimental sarcoma of mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Experiments were carried out in vitro on adriamycin (ADR) accumulation and cytotoxicity alone and in combination with calcium channel antagonist, verapamil (VRP), in ascites murine tumour models of Ehrlich carcinoma (EAC), sarcoma 180 (S180) and P388 lymphocytic leukaemia (P388)." | 7.67 | Modulation of in vitro response to adriamycin by verapamil in murine P388 leukaemia, Ehrlich ascites carcinoma and sarcoma 180. ( Basrur, VS; Chitnis, MP; Pradhan, SG; Tantri, SK, 1987) |
| "The cytotoxic effect of bouvardin (BVD) a protein synthesis inhibitor was studied separately and in combination with verapamil (VRP), a vasodilator and hyperthermia (43 degrees C) against Sarcoma 180 (S 180) and Ehrlich ascites carcinoma (EAC) tumour cells in vitro." | 7.67 | Enhancement of the in vitro cytotoxicity of bouvardin by verapamil alone and combined with hyperthermia in Sarcoma 180 and Ehrlich ascites carcinoma cells. ( Adwankar, MK; Chitnis, MP, 1986) |
| "Reversal of natural resistance to bouvardin (NSC 259968) has been attained in vitro and in vivo, by the calcium influx blocker verapamil in sarcoma 180 cells insensitive to bouvardin." | 7.67 | Reversal of natural resistance to bouvardin (NSC 259968) in sarcoma 180 cells in vitro and in vivo by verapamil. ( Adwankar, MK; Basrur, VS; Chitnis, MP; Menon, RS; Satyamoorthy, K, 1985) |
| "Sarcoma 180 (S180) cells pretreated with verapamil increase their resistance to doxorubicin in vitro." | 3.68 | Resistance to doxorubicin in tumor cells in vitro and in vivo after pretreatment with verapamil. ( Donenko, FV; Efferth, T; Mattern, J; Moroz, LV; Volm, M, 1991) |
| "Experiments were carried out in vitro on adriamycin (ADR) accumulation and cytotoxicity alone and in combination with calcium channel antagonist, verapamil (VRP), in ascites murine tumour models of Ehrlich carcinoma (EAC), sarcoma 180 (S180) and P388 lymphocytic leukaemia (P388)." | 3.67 | Modulation of in vitro response to adriamycin by verapamil in murine P388 leukaemia, Ehrlich ascites carcinoma and sarcoma 180. ( Basrur, VS; Chitnis, MP; Pradhan, SG; Tantri, SK, 1987) |
| "The cytotoxic effect of bouvardin (BVD) a protein synthesis inhibitor was studied separately and in combination with verapamil (VRP), a vasodilator and hyperthermia (43 degrees C) against Sarcoma 180 (S 180) and Ehrlich ascites carcinoma (EAC) tumour cells in vitro." | 3.67 | Enhancement of the in vitro cytotoxicity of bouvardin by verapamil alone and combined with hyperthermia in Sarcoma 180 and Ehrlich ascites carcinoma cells. ( Adwankar, MK; Chitnis, MP, 1986) |
| "Verapamil was found to increase the G2 blocking effect of bleomycin A5 prominently in mouse S-180 and human HEP-2 cell lines." | 1.28 | [Mechanism of enhancement of bleomycin A5 antitumor activity by verapamil]. ( He, NG; Liu, ZM; Song, PG; Xue, SB; Zhang, HQ, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, T | 1 |
| Gao, C | 1 |
| Guo, Y | 1 |
| Donenko, FV | 1 |
| Efferth, T | 1 |
| Mattern, J | 1 |
| Moroz, LV | 1 |
| Volm, M | 1 |
| He, NG | 2 |
| Zhang, HQ | 2 |
| Song, PG | 1 |
| Liu, ZM | 1 |
| Xue, SB | 2 |
| Wang, RH | 1 |
| Yang, XL | 1 |
| Pradhan, SG | 1 |
| Chitnis, MP | 3 |
| Basrur, VS | 2 |
| Tantri, SK | 1 |
| Adwankar, MK | 2 |
| Menon, RS | 1 |
| Satyamoorthy, K | 1 |
7 other studies available for verapamil and Sarcoma 180
| Article | Year |
|---|---|
[Effects of moxibustion on the function of MDR gene product, P-glycoprotein (P-170)].
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Resistance, Mult | 1994 |
Resistance to doxorubicin in tumor cells in vitro and in vivo after pretreatment with verapamil.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Resistance; Leuk | 1991 |
[Mechanism of enhancement of bleomycin A5 antitumor activity by verapamil].
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Drug Synergism; Female; Flow Cytometry; G2 Phase; H | 1991 |
[Enhancement of antitumor activity of bleomycin A5 in mouse sarcoma 180 cells in vitro and in vivo by verapamil].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dru | 1990 |
Modulation of in vitro response to adriamycin by verapamil in murine P388 leukaemia, Ehrlich ascites carcinoma and sarcoma 180.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Survival; Depression, Chemical; DNA, Neoplasm; Do | 1987 |
Enhancement of the in vitro cytotoxicity of bouvardin by verapamil alone and combined with hyperthermia in Sarcoma 180 and Ehrlich ascites carcinoma cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane Perme | 1986 |
Reversal of natural resistance to bouvardin (NSC 259968) in sarcoma 180 cells in vitro and in vivo by verapamil.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Drug Resistance; Mice; Peptides, Cyclic; Sarc | 1985 |