verapamil has been researched along with Pulmonary Consumption in 6 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bedaquiline is a newly approved drug for the treatment of multidrug-resistant tuberculosis, but there are concerns about its safety in humans." | 1.42 | Verapamil increases the bactericidal activity of bedaquiline against Mycobacterium tuberculosis in a mouse model. ( Bishai, WR; Gupta, S; Tyagi, S, 2015) |
| "As verapamil is a substrate for CYP3A4, which is induced by rifampin, we evaluated the pharmacokinetic/pharmacodynamic relationships of verapamil and rifampin coadministration in mice." | 1.39 | Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor. ( Almeida, DV; Ammerman, NC; Bishai, WR; Gupta, S; Maiga, MC; Tyagi, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghajavand, H | 1 |
| Kargarpour Kamakoli, M | 1 |
| Khanipour, S | 1 |
| Pourazar Dizaji, S | 1 |
| Masoumi, M | 1 |
| Rahimi Jamnani, F | 1 |
| Fateh, A | 1 |
| Siadat, SD | 1 |
| Vaziri, F | 1 |
| Gupta, S | 2 |
| Tyagi, S | 2 |
| Almeida, DV | 1 |
| Maiga, MC | 1 |
| Ammerman, NC | 1 |
| Bishai, WR | 2 |
| Li, G | 1 |
| Zhang, J | 1 |
| Li, C | 1 |
| Guo, Q | 1 |
| Jiang, Y | 1 |
| Wei, J | 1 |
| Qiu, Y | 1 |
| Zhao, X | 1 |
| Zhao, LL | 1 |
| Lu, J | 1 |
| Wan, K | 1 |
| Balganesh, M | 1 |
| Dinesh, N | 1 |
| Sharma, S | 1 |
| Kuruppath, S | 1 |
| Nair, AV | 1 |
| Sharma, U | 1 |
| Szumowski, JD | 1 |
| Adams, KN | 1 |
| Edelstein, PH | 1 |
| Ramakrishnan, L | 1 |
6 other studies available for verapamil and Pulmonary Consumption
| Article | Year |
|---|---|
High Prevalence of Bedaquiline Resistance in Treatment-Naive Tuberculosis Patients and Verapamil Effectiveness.
Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Humans; Iran; Membrane Transpor | 2019 |
Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor.
Topics: Adjuvants, Pharmaceutic; Animals; Antitubercular Agents; Calcium Channel Blockers; Drug Therapy, Com | 2013 |
Verapamil increases the bactericidal activity of bedaquiline against Mycobacterium tuberculosis in a mouse model.
Topics: Animals; Antitubercular Agents; Calcium Channel Blockers; Diarylquinolines; Disease Models, Animal; | 2015 |
Antimycobacterial activity of five efflux pump inhibitors against Mycobacterium tuberculosis clinical isolates.
Topics: Adult; Antitubercular Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; China; Chlorpromazine; Huma | 2016 |
Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates.
Topics: Antitubercular Agents; ATP-Binding Cassette Transporters; Bacterial Proteins; Culture Media; Dipepti | 2012 |
Antimicrobial efflux pumps and Mycobacterium tuberculosis drug tolerance: evolutionary considerations.
Topics: Antitubercular Agents; ATP-Binding Cassette Transporters; Biological Transport; Calcium Channel Bloc | 2013 |