Page last updated: 2024-10-24

verapamil and Pulmonary Consumption

verapamil has been researched along with Pulmonary Consumption in 6 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
"Bedaquiline is a newly approved drug for the treatment of multidrug-resistant tuberculosis, but there are concerns about its safety in humans."1.42Verapamil increases the bactericidal activity of bedaquiline against Mycobacterium tuberculosis in a mouse model. ( Bishai, WR; Gupta, S; Tyagi, S, 2015)
"As verapamil is a substrate for CYP3A4, which is induced by rifampin, we evaluated the pharmacokinetic/pharmacodynamic relationships of verapamil and rifampin coadministration in mice."1.39Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor. ( Almeida, DV; Ammerman, NC; Bishai, WR; Gupta, S; Maiga, MC; Tyagi, S, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghajavand, H1
Kargarpour Kamakoli, M1
Khanipour, S1
Pourazar Dizaji, S1
Masoumi, M1
Rahimi Jamnani, F1
Fateh, A1
Siadat, SD1
Vaziri, F1
Gupta, S2
Tyagi, S2
Almeida, DV1
Maiga, MC1
Ammerman, NC1
Bishai, WR2
Li, G1
Zhang, J1
Li, C1
Guo, Q1
Jiang, Y1
Wei, J1
Qiu, Y1
Zhao, X1
Zhao, LL1
Lu, J1
Wan, K1
Balganesh, M1
Dinesh, N1
Sharma, S1
Kuruppath, S1
Nair, AV1
Sharma, U1
Szumowski, JD1
Adams, KN1
Edelstein, PH1
Ramakrishnan, L1

Other Studies

6 other studies available for verapamil and Pulmonary Consumption

ArticleYear
High Prevalence of Bedaquiline Resistance in Treatment-Naive Tuberculosis Patients and Verapamil Effectiveness.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:3

    Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Humans; Iran; Membrane Transpor

2019
Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor.
    American journal of respiratory and critical care medicine, 2013, Sep-01, Volume: 188, Issue:5

    Topics: Adjuvants, Pharmaceutic; Animals; Antitubercular Agents; Calcium Channel Blockers; Drug Therapy, Com

2013
Verapamil increases the bactericidal activity of bedaquiline against Mycobacterium tuberculosis in a mouse model.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1

    Topics: Animals; Antitubercular Agents; Calcium Channel Blockers; Diarylquinolines; Disease Models, Animal;

2015
Antimycobacterial activity of five efflux pump inhibitors against Mycobacterium tuberculosis clinical isolates.
    The Journal of antibiotics, 2016, Volume: 69, Issue:3

    Topics: Adult; Antitubercular Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; China; Chlorpromazine; Huma

2016
Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:5

    Topics: Antitubercular Agents; ATP-Binding Cassette Transporters; Bacterial Proteins; Culture Media; Dipepti

2012
Antimicrobial efflux pumps and Mycobacterium tuberculosis drug tolerance: evolutionary considerations.
    Current topics in microbiology and immunology, 2013, Volume: 374

    Topics: Antitubercular Agents; ATP-Binding Cassette Transporters; Biological Transport; Calcium Channel Bloc

2013