Page last updated: 2024-10-24

verapamil and Pre-Eclampsia

verapamil has been researched along with Pre-Eclampsia in 11 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.

Research Excerpts

ExcerptRelevanceReference
"Preeclampsia is associated with increased peripheral, uterine, and umbilical artery resistance."5.29The effect of acute volume expansion and vasodilatation with verapamil on uterine and umbilical artery Doppler indices in severe preeclampsia. ( Akovic, K; Anthony, J; Belfort, M; Kirshon, B; Moise, K; Saade, G, 1994)
" Volume loading with 400 +/- 114 ml dextran-70 normalized these variables, and subsequent vasodilatation with verapamil did not reduce these indices below the normal limits for pregnancy."3.68Respiratory function in severe gestational proteinuric hypertension: the effects of rapid volume expansion and subsequent vasodilatation with verapamil. ( Anthony, J; Belfort, MA; Kirshon, B, 1991)
"Verapamil was initiated, and at 1 month there was improvement intracranially, but cervical vertebral arterial narrowing, likely dissection, was discovered."3.01Reversible cerebral vasoconstriction syndrome in the postpartum period: A case report and review of the literature. ( Collins, R; Krishnan, A; Lee, DE, 2023)
"Part 2: RBC-deformability in preeclampsia was reduced as predicted by previous studies (0."2.71Effect of magnesium on red blood cell deformability in pregnancy. ( Abele, H; Aydeniz, B; Becker, S; Klever, T; Schauf, B; Wallwiener, D, 2005)
"Preeclampsia is associated with increased peripheral, uterine, and umbilical artery resistance."1.29The effect of acute volume expansion and vasodilatation with verapamil on uterine and umbilical artery Doppler indices in severe preeclampsia. ( Akovic, K; Anthony, J; Belfort, M; Kirshon, B; Moise, K; Saade, G, 1994)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's4 (36.36)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Lee, DE1
Krishnan, A1
Collins, R1
Chen, Q1
Guo, F1
Liu, S1
Xiao, J1
Wang, C1
Snowise, S1
Stone, PR1
Chamley, LW1
Schauf, B1
Becker, S1
Abele, H1
Klever, T1
Wallwiener, D1
Aydeniz, B1
Belfort, M1
Akovic, K1
Anthony, J3
Saade, G1
Kirshon, B2
Moise, K1
Gromyko, GL1
Serafini, PC2
Petracco, A2
Vicosa Júnior, HM1
Costa, PL2
Viçosa, HM1
Barcelos, LF1
Belfort, MA2
Buccimazza, A1
Davey, DA1
Norris, MC1
Rose, JC1
Dewan, DM1
Brittinger, WD1
Schwarzbeck, A1
Wittenmeier, KW1
Twittenhoff, WD1
Stegaru, B1
Huber, W1
Ewald, RW1
von Henning, GE1
Fabricius, M1
Strauch, M1

Reviews

1 review available for verapamil and Pre-Eclampsia

ArticleYear
Reversible cerebral vasoconstriction syndrome in the postpartum period: A case report and review of the literature.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2023, Volume: 162, Issue:3

    Topics: Adult; Female; Humans; Magnetic Resonance Imaging; Postpartum Period; Pre-Eclampsia; Pregnancy; Vaso

2023

Trials

1 trial available for verapamil and Pre-Eclampsia

ArticleYear
Effect of magnesium on red blood cell deformability in pregnancy.
    Hypertension in pregnancy, 2005, Volume: 24, Issue:1

    Topics: Adult; Cells, Cultured; Double-Blind Method; Drug Therapy, Combination; Erythrocyte Deformability; F

2005

Other Studies

9 other studies available for verapamil and Pre-Eclampsia

ArticleYear
Calcium channel blockers prevent endothelial cell activation in response to necrotic trophoblast debris: possible relevance to pre-eclampsia.
    Cardiovascular research, 2012, Dec-01, Volume: 96, Issue:3

    Topics: Adolescent; Adult; Calcium Channel Blockers; Case-Control Studies; Cell Adhesion; Cell Proliferation

2012
The effect of acute volume expansion and vasodilatation with verapamil on uterine and umbilical artery Doppler indices in severe preeclampsia.
    Journal of clinical ultrasound : JCU, 1994, Volume: 22, Issue:5

    Topics: Adult; Arteries; Blood Flow Velocity; Blood Pressure; Blood Volume; Cardiac Output; Dextrans; Female

1994
[Changes in cardiohemodynamic indicators during use of verapamil for preventing and treating hypertensive complications of pregnancy].
    Biulleten' eksperimental'noi biologii i meditsiny, 1995, Volume: 120, Issue:11

    Topics: Adolescent; Adult; Antihypertensive Agents; Female; Hemodynamics; Humans; Hypertension; Pre-Eclampsi

1995
[Arterial hypotensive effect of verapamil in severe pre-eclampsia. Preliminary study].
    Arquivos brasileiros de cardiologia, 1979, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Blood Pressure; Electrocardiography; Female; Fetal Heart; Heart Rate; Humans; Pre

1979
[Verapamil and severe pre-eclampsia. Plasma and urinary levels of urea, creatinine, sodium, potassium, chloride and calcium].
    Arquivos brasileiros de cardiologia, 1978, Volume: 31 Suppl 1

    Topics: Calcium; Chlorides; Creatinine; Female; Glomerular Filtration Rate; Humans; Potassium; Pre-Eclampsia

1978
Hemodynamic changes associated with intravenous infusion of the calcium antagonist verapamil in the treatment of severe gestational proteinuric hypertension.
    Obstetrics and gynecology, 1990, Volume: 75, Issue:6

    Topics: Adult; Blood Pressure; Central Venous Pressure; Dextrans; Female; Fluid Therapy; Hemodynamics; Human

1990
Respiratory function in severe gestational proteinuric hypertension: the effects of rapid volume expansion and subsequent vasodilatation with verapamil.
    British journal of obstetrics and gynaecology, 1991, Volume: 98, Issue:10

    Topics: Blood Volume; Dextrans; Drug Therapy, Combination; Female; Hemodynamics; Humans; Oxygen Consumption;

1991
Nifedipine or verapamil counteracts hypertension in gravid ewes.
    Anesthesiology, 1986, Volume: 65, Issue:3

    Topics: Animals; Blood Gas Analysis; Female; Hypertension; Nifedipine; Norepinephrine; Pre-Eclampsia; Pregna

1986
[Clinical experimental studies on the blood pressure reducing effect of verapamil].
    Deutsche medizinische Wochenschrift (1946), 1970, Sep-11, Volume: 95, Issue:37

    Topics: Adult; Anti-Arrhythmia Agents; Blood Circulation; Blood Pressure; Electrocardiography; Female; Femor

1970