verapamil has been researched along with Plasmodium falciparum Malaria in 10 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ellagic acid is a polyphenol found in various plant products." | 1.35 | In vitro and in vivo properties of ellagic acid in malaria treatment. ( Benoit-Vical, F; Berry, A; Garcia-Alvarez, MC; Nicolau, ML; Olagnier, D; Soh, PN; Witkowski, B, 2009) |
| "Control of falciparum malaria has become almost impossible in many areas due to the development of resistance to chloroquine and other antimalarial drugs." | 1.29 | Relationship of global chloroquine transport and reversal of resistance in Plasmodium falciparum. ( Boulter, MK; Bray, PG; Howells, RE; Ritchie, GY; Ward, SA, 1994) |
| "Cyproheptadine and verapamil were not effective in reversing chloroquine resistance and probable drug toxicity was observed with these drugs in combination with chloroquine." | 1.29 | Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys. ( Kyle, DE; Milhous, WK; Rossan, RN, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soh, PN | 1 |
| Witkowski, B | 2 |
| Olagnier, D | 1 |
| Nicolau, ML | 1 |
| Garcia-Alvarez, MC | 1 |
| Berry, A | 1 |
| Benoit-Vical, F | 1 |
| Ross, LS | 1 |
| Dhingra, SK | 1 |
| Mok, S | 1 |
| Yeo, T | 1 |
| Wicht, KJ | 1 |
| Kümpornsin, K | 1 |
| Takala-Harrison, S | 1 |
| Fairhurst, RM | 1 |
| Ariey, F | 1 |
| Menard, D | 1 |
| Fidock, DA | 1 |
| Ciach, M | 1 |
| Zong, K | 1 |
| Kain, KC | 1 |
| Crandall, I | 1 |
| Chen, N | 1 |
| Kyle, DE | 2 |
| Pasay, C | 1 |
| Fowler, EV | 1 |
| Baker, J | 1 |
| Peters, JM | 1 |
| Cheng, Q | 1 |
| Tamez, PA | 1 |
| Lantvit, D | 1 |
| Lim, E | 1 |
| Pezzuto, JM | 1 |
| Bray, PG | 2 |
| Boulter, MK | 1 |
| Ritchie, GY | 1 |
| Howells, RE | 1 |
| Ward, SA | 2 |
| Milhous, WK | 1 |
| Rossan, RN | 1 |
| Adovelande, J | 1 |
| Delèze, J | 1 |
| Schrével, J | 1 |
| Mungthin, M | 1 |
| Rafatro, H | 1 |
| Ramanitrahasimbola, D | 1 |
| Rasoanaivo, P | 1 |
| Ratsimamanga-Urverg, S | 1 |
| Rakoto-Ratsimamanga, A | 1 |
| Frappier, F | 1 |
10 other studies available for verapamil and Plasmodium falciparum Malaria
| Article | Year |
|---|---|
In vitro and in vivo properties of ellagic acid in malaria treatment.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Chloroquine; Dose-Response Relationshi | 2009 |
Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine.
Topics: Animals; Antimalarials; Cambodia; Cell Shape; Chloroquine; Drug Resistance; Gene Dosage; Gene Editin | 2018 |
Reversal of mefloquine and quinine resistance in Plasmodium falciparum with NP30.
Topics: Animals; Antimalarials; Calcium Channel Blockers; Drug Resistance; Genotype; Humans; Malaria, Falcip | 2003 |
pfcrt Allelic types with two novel amino acid mutations in chloroquine-resistant Plasmodium falciparum isolates from the Philippines.
Topics: Alleles; Amino Acid Substitution; Amino Acids; Animals; Antimalarials; Calcium Channel Blockers; Chl | 2003 |
Chemosensitizing action of cepharanthine against drug-resistant human malaria, Plasmodium falciparum.
Topics: Alkaloids; Animals; Benzylisoquinolines; Chloroquine; Disease Models, Animal; Dose-Response Relation | 2005 |
Relationship of global chloroquine transport and reversal of resistance in Plasmodium falciparum.
Topics: Animals; Biological Transport, Active; Chloroquine; Desipramine; Drug Resistance; Humans; Hydrogen-I | 1994 |
Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys.
Topics: Animals; Aotus trivirgatus; Calcium Channel Blockers; Chloroquine; Chlorpromazine; Cyproheptadine; D | 1993 |
Synergy between two calcium channel blockers, verapamil and fantofarone (SR33557), in reversing chloroquine resistance in Plasmodium falciparum.
Topics: Animals; Antimalarials; Calcium Channel Blockers; Chloroquine; Dose-Response Relationship, Drug; Dru | 1998 |
Phenotypic and genotypic characteristics of recently adapted isolates of Plasmodium falciparum from Thailand.
Topics: Animals; Antimalarials; Blotting, Western; Chloroquine; DNA Fingerprinting; DNA, Protozoan; Drug Res | 1999 |
Reversal activity of the naturally occurring chemosensitizer malagashanine in Plasmodium malaria.
Topics: Alkaloids; Animals; Antimalarials; Chloroquine; Disease Models, Animal; Drug Interactions; Drug Resi | 2000 |