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verapamil and Pituitary Neoplasms

verapamil has been researched along with Pituitary Neoplasms in 22 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.

Research Excerpts

ExcerptRelevanceReference
"Verapamil stimulation test was previously investigated as a tool for differential diagnosis of hyperprolactinemia, but with conflicting results."7.76Verapamil stimulation test in hyperprolactinemia: loss of prolactin response in anatomic or functional stalk effect. ( Dagdelen, S; Usman, A, 2010)
"To describe a patient with an incidental pituitary lesion who experienced verapamil-induced hyperprolactinemia."7.69Verapamil-induced hyperprolactinemia complicated by a pituitary incidentaloma. ( Aron, DC; Dombrowski, RC; Romeo, JH, 1995)
"Verapamil stimulation test was previously investigated as a tool for differential diagnosis of hyperprolactinemia, but with conflicting results."3.76Verapamil stimulation test in hyperprolactinemia: loss of prolactin response in anatomic or functional stalk effect. ( Dagdelen, S; Usman, A, 2010)
"To describe a patient with an incidental pituitary lesion who experienced verapamil-induced hyperprolactinemia."3.69Verapamil-induced hyperprolactinemia complicated by a pituitary incidentaloma. ( Aron, DC; Dombrowski, RC; Romeo, JH, 1995)
"Cluster headache is classified as a primary headache by definition not caused by an underlying pathology."1.43Chronic cluster headache and the pituitary gland. ( De Pue, A; Lutin, B; Paemeleire, K, 2016)
"Magnetic resonance imaging showed a pituitary adenoma which invaded into right cavernous sinus."1.33[Cluster like headache in a patient with the Maffucci's syndrome]. ( Imai, N; Kitamura, E; Konisi, T; Okabe, T; Serizawa, M; Suzuki, Y, 2006)
"Serum from patients with IDDM increased L-type calcium channel activity of insulin-producing cells and of GH3 cells derived from a pituitary tumor."1.29Increased activity of L-type Ca2+ channels exposed to serum from patients with type I diabetes. ( Ammälä, C; Bokvist, K; Dypbukt, J; Hallberg, A; Juntti-Berggren, L; Larsson, O; Nicotera, P; Orrenius, S; Rorsman, P; Wåhlander, K, 1993)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199013 (59.09)18.7374
1990's5 (22.73)18.2507
2000's2 (9.09)29.6817
2010's2 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Pue, A1
Lutin, B1
Paemeleire, K1
Dagdelen, S1
Usman, A1
Kitamura, E1
Imai, N1
Konisi, T1
Suzuki, Y1
Serizawa, M1
Okabe, T1
Kozminski, M1
Gershengorn, MC3
Ozawa, S1
Kimura, N1
Albert, PR1
Tashjian, AH2
Geras, E1
Rebecchi, MJ1
Juntti-Berggren, L1
Larsson, O1
Rorsman, P1
Ammälä, C1
Bokvist, K1
Wåhlander, K1
Nicotera, P1
Dypbukt, J1
Orrenius, S1
Hallberg, A1
Jancis, EM1
Carbone, R1
Loechner, KJ1
Dannies, PS1
Dombrowski, RC1
Romeo, JH1
Aron, DC1
Yang, JP1
Sato, N1
Wang, XB1
Greer, MA1
Greer, SE1
McAdams, S1
Oshima, T1
Richardson, UI1
Heisler, S1
Sletholt, K1
Haug, E1
Gautvik, KM1
Schettini, G1
Meucci, O1
Florio, T1
Grimaldi, M1
Landolfi, E1
Magri, G1
Yasumoto, T1
Davis, JR1
Vidal, ME1
Wilson, EM1
Sheppard, MC1
Wolfe, SE1
Brostrom, CO1
Brostrom, MA1
De Marinis, L1
Mancini, A1
Minnielli, S1
D'Amico, C1
Di Pietro, ML1
Albini, C1
Passeri, M1
Liberale, I1
Menini, E1
Barbarino, A1
Thaw, C1
Enyeart, JJ1
Aizawa, T1
Hinkle, PM1

Reviews

1 review available for verapamil and Pituitary Neoplasms

ArticleYear
Thyrotropin releasing hormone. A review of the mechanisms of acute stimulation of pituitary hormone release.
    Molecular and cellular biochemistry, 1982, Jun-25, Volume: 45, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cells, Cultured; Chlortetracycline; Cyclic AMP; Guany

1982

Other Studies

21 other studies available for verapamil and Pituitary Neoplasms

ArticleYear
Chronic cluster headache and the pituitary gland.
    The journal of headache and pain, 2016, Volume: 17

    Topics: Adenoma; Cabergoline; Central Nervous System Cysts; Cluster Headache; Diagnosis, Differential; Dopam

2016
Verapamil stimulation test in hyperprolactinemia: loss of prolactin response in anatomic or functional stalk effect.
    Minerva endocrinologica, 2010, Volume: 35, Issue:2

    Topics: Adult; Biomarkers; Case-Control Studies; Diagnosis, Differential; Female; Humans; Hyperprolactinemia

2010
[Cluster like headache in a patient with the Maffucci's syndrome].
    No to shinkei = Brain and nerve, 2006, Volume: 58, Issue:6

    Topics: Adenoma; Cluster Headache; Enchondromatosis; Humans; Magnetic Resonance Imaging; Male; Middle Aged;

2006
Resident and fellow section. Expert opinion: trigeminal autonomic cephalgia post transsphenoidal surgery.
    Headache, 2008, Volume: 48, Issue:4

    Topics: Adenoma; Adrenal Insufficiency; Adult; Analgesics; Anticonvulsants; Carbamazepine; Diabetes Insipidu

2008
Calcium channel and prolactin release in rat clonal pituitary cells: effects of verapamil.
    The American journal of physiology, 1982, Volume: 243, Issue:1

    Topics: Action Potentials; Animals; Calcium; Cell Line; Ion Channels; Kinetics; Pituitary Neoplasms; Prolact

1982
Relationship of thyrotropin-releasing hormone-induced spike and plateau phases in cytosolic free Ca2+ concentrations to hormone secretion. Selective blockade using ionomycin and nifedipine.
    The Journal of biological chemistry, 1984, Dec-25, Volume: 259, Issue:24

    Topics: Animals; Calcium; Cell Line; Cytosol; Ethers; Growth Hormone; Ionomycin; Kinetics; Nifedipine; Pitui

1984
Evidence that stimulation of thyrotropin and prolactin secretion by thyrotropin-releasing hormone occur via different calcium-mediated mechanisms: studies with verapamil.
    Endocrinology, 1982, Volume: 110, Issue:3

    Topics: Animals; Biological Transport, Active; Calcium; Kinetics; Mice; Neoplasms, Experimental; Pituitary N

1982
Increased activity of L-type Ca2+ channels exposed to serum from patients with type I diabetes.
    Science (New York, N.Y.), 1993, Jul-02, Volume: 261, Issue:5117

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Estradiol induction of rhodamine 123 efflux and the multidrug resistance pump in rat pituitary tumor cells.
    Molecular pharmacology, 1993, Volume: 43, Issue:1

    Topics: Animals; Cyclosporins; Drug Resistance; Estradiol; Pituitary Neoplasms; Rats; Rhodamine 123; Rhodami

1993
Verapamil-induced hyperprolactinemia complicated by a pituitary incidentaloma.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:10

    Topics: Aged; Calcium Channel Blockers; Erectile Dysfunction; Humans; Hyperprolactinemia; Magnetic Resonance

1995
Platelet-activating factor affects cytosolic free calcium concentration and prolactin secretion in GH4C1 rat pituitary cells.
    Biochemical and biophysical research communications, 1991, Jan-31, Volume: 174, Issue:2

    Topics: Animals; Calcium; Calcium Channels; Cell Line; Diterpenes; Dose-Response Relationship, Drug; Egtazic

1991
Medium hyposmolarity stimulates prolactin secretion in GH4C1 cells by inducing an increase in cytosolic free calcium.
    Endocrinology, 1990, Volume: 127, Issue:2

    Topics: Animals; Calcium; Cell Line; Culture Media; Cytosol; Hypotonic Solutions; Kinetics; Nifedipine; Pitu

1990
Multiple classes of calcium channels in mouse pituitary tumor cells.
    Life sciences, 1986, Jan-06, Volume: 38, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Calcium; Cell Membrane; Clone Cells; Cobalt; Corticotropin-Rel

1986
BAY-K-8644-stimulated cyclic GMP synthesis in mouse pituitary tumor cells.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
On the involvement of cyclic AMP and extracellular Ca2+ in the regulation of hormone release from rat pituitary tumour (GH3) cells in culture.
    Bioscience reports, 1987, Volume: 7, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Calcium; Cell Line; Cobalt; Cyclic AM

1987
Pertussis toxin pretreatment abolishes dihydropyridine inhibition of calcium flux in the 235-1 pituitary cell line.
    Biochemical and biophysical research communications, 1988, Feb-29, Volume: 151, Issue:1

    Topics: Animals; Calcium; Dihydropyridines; Ion Channels; Marine Toxins; Nicardipine; Oxocins; Pertussis Tox

1988
Calcium dependence of prolactin mRNA accumulation in GH3 rat pituitary tumour cells.
    Journal of molecular endocrinology, 1988, Volume: 1, Issue:2

    Topics: Calcium; Cell Line; Cobalt; Hybridization, Genetic; Immunoblotting; Pituitary Neoplasms; Prolactin;

1988
Mechanisms of action of inhibitors of prolactin secretion in GH3 pituitary cells. I. Ca2+-dependent inhibition of amino acid incorporation.
    Molecular pharmacology, 1986, Volume: 29, Issue:4

    Topics: Acetylcholine; Amino Acids; Animals; Bromocriptine; Calcium; Carbachol; Cell Line; Chlorpromazine; I

1986
Calcium antagonists and hormone release. V. Effects of a calcium-antagonist (verapamil) on pituitary hormone release in hypersecretory states.
    Hormone research, 1987, Volume: 25, Issue:1

    Topics: Acromegaly; Adolescent; Adult; Cushing Syndrome; Female; Humans; Hypogonadism; Hypothyroidism; Male;

1987
Thyrotropin-releasing hormone (TRH) stimulates biphasic elevation of cytoplasmic free calcium in GH3 cells. Further evidence that TRH mobilizes cellular and extracellular Ca2+.
    Endocrinology, 1985, Volume: 116, Issue:2

    Topics: Aminoquinolines; Animals; Calcium; Cell Line; Cytoplasm; Extracellular Space; Fluorescent Dyes; Nife

1985
Dihydropyridine Ca2+ antagonists: potent inhibitors of secretion from normal and transformed pituitary cells.
    The American journal of physiology, 1985, Volume: 248, Issue:5 Pt 1

    Topics: Animals; Calcium Channel Blockers; Cell Line; Growth Hormone; Nicotinic Acids; Nifedipine; Nimodipin

1985