verapamil has been researched along with Pheochromocytoma in 18 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| " This article describes the case of a patient affected by pheochromocytoma in whom multiple organ failure developed after contemporary administration of ergotamine, caffeine, and nimesulide." | 7.69 | Pheochromocytoma crisis caused by contemporary ergotamine, caffeine, and nimesulide administration. ( Bartoli, P; Bonechi, F; Brandinelli, A; Del Rosso, A; Fradella, G; Ieri, A; Maioli, M; Mannelli, M; Mazza, F; Russo, L; Sansoni, M; Zipoli, A, 1997) |
| " This article describes the case of a patient affected by pheochromocytoma in whom multiple organ failure developed after contemporary administration of ergotamine, caffeine, and nimesulide." | 3.69 | Pheochromocytoma crisis caused by contemporary ergotamine, caffeine, and nimesulide administration. ( Bartoli, P; Bonechi, F; Brandinelli, A; Del Rosso, A; Fradella, G; Ieri, A; Maioli, M; Mannelli, M; Mazza, F; Russo, L; Sansoni, M; Zipoli, A, 1997) |
| "The mechanism of calcium channel antagonism by phenytoin was studied by comparing the effects of phenytoin and classical calcium channel antagonists on K+-stimulated 45Ca uptake and [3H]nitrendipine binding in the PC12 pheochromocytoma cell line." | 3.67 | Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists. ( Carpenter, CL; Greenberg, DA; Messing, RO, 1985) |
| " We report that verapamil reversibly inhibits binding of the nicotinic receptor probe 125I-alpha-bungarotoxin to membranes from rat brain, Torpedo californica, the rat pheochromocytoma cell line PC12 and the human medulloblastoma cell line TE671, with Ki values of 24." | 3.67 | Allosteric modification of alpha-bungarotoxin binding by the 'calcium channel antagonist' verapamil. ( Lukas, RJ; Siegel, HN, 1986) |
| "Effects of maitotoxin, the most potent marine toxin, were studied using a rat pheochromocytoma cell line, PC12h." | 3.66 | Maitotoxin, a Ca2+ channel activator candidate. ( Ohizumi, Y; Takahashi, M; Yasumoto, T, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (72.22) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Henry, A | 1 |
| Charpiat, B | 1 |
| Vial, T | 1 |
| Franchini, S | 1 |
| Cuilleret, FJ | 1 |
| Milon, H | 1 |
| Takahashi, M | 1 |
| Ohizumi, Y | 1 |
| Yasumoto, T | 1 |
| Grasso, A | 1 |
| Alemà , S | 1 |
| Rufini, S | 1 |
| Senni, MI | 1 |
| Del Rosso, A | 1 |
| Fradella, G | 1 |
| Russo, L | 1 |
| Bartoli, P | 1 |
| Bonechi, F | 1 |
| Brandinelli, A | 1 |
| Maioli, M | 1 |
| Mazza, F | 1 |
| Sansoni, M | 1 |
| Zipoli, A | 1 |
| Mannelli, M | 2 |
| Ieri, A | 1 |
| Krylov, IuF | 1 |
| Astashkin, EI | 1 |
| Smirnov, ON | 1 |
| Grivennikov, IA | 1 |
| Glezer, SV | 1 |
| Sobolev, KE | 1 |
| Grachev, SV | 1 |
| Muliar, AG | 1 |
| Haas, Th | 1 |
| Denkl, P | 1 |
| Chalfie, M | 1 |
| Hoadley, D | 1 |
| Pastan, S | 1 |
| Perlman, RL | 1 |
| Smets, LA | 1 |
| Janssen, M | 1 |
| Rutgers, M | 1 |
| Ritzen, K | 1 |
| Buttenhuis, C | 1 |
| Kauffman, FC | 1 |
| Davis, LH | 1 |
| Whittaker, M | 1 |
| Messing, RO | 1 |
| Carpenter, CL | 1 |
| Greenberg, DA | 1 |
| Oldham, SB | 1 |
| Ritchie, T | 1 |
| Noble, EP | 1 |
| Villani, A | 1 |
| Primieri, P | 1 |
| De Cosmo, G | 1 |
| Baraka, A | 1 |
| Usta, N | 1 |
| Yamut, F | 1 |
| Haroun, S | 1 |
| Siegel, HN | 1 |
| Lukas, RJ | 1 |
| DeFeo, ML | 1 |
| Maggi, M | 1 |
| Geppetti, P | 1 |
| Baldi, E | 1 |
| Pupilli, C | 1 |
| Serio, M | 1 |
| Guazzi, MD | 1 |
| De Cesare, N | 1 |
| Galli, C | 1 |
| Salvioni, A | 1 |
| Tamborini, G | 1 |
| Tosi, E | 1 |
| Philipp, T | 1 |
| Nast, HP | 1 |
| Heinrich, F | 1 |
| Schultis, K | 1 |
1 review available for verapamil and Pheochromocytoma
| Article | Year |
|---|---|
Ethanol exposure alters K+- but not bradykinin-induced dopamine release in PC12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
2 trials available for verapamil and Pheochromocytoma
| Article | Year |
|---|---|
Effect of verapamil on catecholamine secretion by human pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Catecholamines; Humans; Pheochromocytoma; Verapamil | 1986 |
[Nifedipine as a vasodilator antihypertensive with a rapid action].
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Brain Diseases; Cardiomyopathies; Emergencies; Hem | 1985 |
15 other studies available for verapamil and Pheochromocytoma
| Article | Year |
|---|---|
Pheochromocytoma unmasked by amisulpride and tiapride.
Topics: Adult; Amisulpride; Antipsychotic Agents; Calcium Channel Blockers; Headache; Humans; Hypertension; | 2005 |
Maitotoxin, a Ca2+ channel activator candidate.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Cell Line; Ion Channels; Kinetics; Manganese; Marine Toxi | 1982 |
Black widow spider toxin-induced calcium fluxes and transmitter release in a neurosecretory cell line.
Topics: Animals; Arthropod Venoms; Biological Transport; Calcium; Cell Line; Cytosol; Dopamine; Exocytosis; | 1980 |
Pheochromocytoma crisis caused by contemporary ergotamine, caffeine, and nimesulide administration.
Topics: Adrenal Gland Neoplasms; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; A | 1997 |
[Regulating activity of plasma membranous Ca2+ channels in PC-12 pheochromocytoma cells with chemicals and pharmaceutic agents].
Topics: Adrenal Gland Neoplasms; Animals; Arachidonic Acid; Calcium; Calcium Channel Blockers; Calcium Chann | 1999 |
[Therapy of hypertensive crises].
Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine | 1977 |
Calcium uptake into rat pheochromocytoma cells.
Topics: Animals; Calcium; Catecholamines; Drug Interactions; In Vitro Techniques; Phenytoin; Pheochromocytom | 1976 |
Pharmacokinetics and intracellular distribution of the tumor-targeted radiopharmaceutical m-iodo-benzylguanidine in SK-N-SH neuroblastoma and PC-12 pheochromocytoma cells.
Topics: 3-Iodobenzylguanidine; Acetylcholine; Adrenal Gland Neoplasms; Animals; Antineoplastic Agents; Autor | 1991 |
Activation of glycogen phosphorylase in rat pheochromocytoma PC12 cells and isolated hepatocytes by organophosphates.
Topics: Adenine Nucleotides; Animals; Calcium; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; D | 1990 |
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell | 1985 |
Cardiomyopathy in phaeochromocytoma: a case report.
Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, Inhalation; Cardiomyopathies; Humans; Male; Multiple End | 1989 |
Verapamil may not be the drug of choice for control of hemodynamic changes during surgical excision of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Female; Hemodynamics; Humans; Pheochromocytoma; Verapamil | 1987 |
Allosteric modification of alpha-bungarotoxin binding by the 'calcium channel antagonist' verapamil.
Topics: Allosteric Site; Animals; Binding Sites; Binding, Competitive; Brain; Bungarotoxins; Cell Line; Huma | 1986 |
[Hypertensive emergencies].
Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies; | 1974 |
[Therapy of hypertension].
Topics: Adrenal Gland Neoplasms; Aniline Compounds; Antihypertensive Agents; Diuretics; Female; Guanethidine | 1971 |