verapamil has been researched along with Pancreatitis in 13 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the role of phospholipase A(2) (PLA(2)) in injury of lung complicated by acute pancreatitis (AP) and the therapeutic effect of verapamil, furthermore to explore its possible mechanism." | 7.72 | [Role of phospholipase A2 in injury of lung complicated by acute pancreatitis and the therapeutic effect and mechanism of verapamil on it]. ( Li, YY; Zhang, H, 2003) |
| " We studied the effects of verapamil on pancreatic ultrastructure and zymogen extraction during diet-induced acute pancreatitis." | 7.69 | Dose-dependent effect of continuous subcutaneous verapamil infusion on experimental acute pancreatitis in mice. ( Lake-Bakaar, G; Lyubsky, S, 1995) |
| "We studied the effects of the calcium channel blocker, verapamil on experimental acute pancreatitis (AP) in rats." | 7.68 | [Effects of verapamil on prostacyclin, thromboxane and pancreatic blood flow of rats with experimental acute pancreatitis]. ( Shen, J, 1991) |
| "Verapamil treatment decreased significantly tissue activity of trypsin (p less than 0." | 5.28 | [The effects of verapamil in experimental acute pancreatitis in the rat]. ( Díez Miralles, M; González Santos, J; Graells Ferrer, ML; Medrano Heredia, J; Pardo Correcher, JM; Regalado Pareja, RI; Ruiz Macía, JA, 1992) |
| "Fifty healthy Sprague-Dawley rats were randomly divided into control, severe acute pancreatitis (SAP), Qingyi decoction-treated (QYT), dexamethasone-treated (DEX), and verapamil-treated (VER) groups." | 3.81 | Therapeutic effect of Qingyi decoction in severe acute pancreatitis-induced intestinal barrier injury. ( Chen, HL; Liu, GL; Owusu, L; Wang, GY; Wang, YX; Xu, CM; Zhang, GX; Zhang, JW, 2015) |
| "To investigate the role of phospholipase A(2) (PLA(2)) in injury of lung complicated by acute pancreatitis (AP) and the therapeutic effect of verapamil, furthermore to explore its possible mechanism." | 3.72 | [Role of phospholipase A2 in injury of lung complicated by acute pancreatitis and the therapeutic effect and mechanism of verapamil on it]. ( Li, YY; Zhang, H, 2003) |
| " We studied the effects of verapamil on pancreatic ultrastructure and zymogen extraction during diet-induced acute pancreatitis." | 3.69 | Dose-dependent effect of continuous subcutaneous verapamil infusion on experimental acute pancreatitis in mice. ( Lake-Bakaar, G; Lyubsky, S, 1995) |
| "The effect of verapamil administration on the changes of prostanoid synthesis, and on free radical production associated with acute pancreatitis, has been evaluated." | 3.69 | Calcium channel blockers in experimental acute pancreatitis: effect on tissue prostanoids and oxygen free radicals. ( Bulbena, O; Closa, D; Gelpi, E; Hotter, G; Rosello-Catafau, J, 1996) |
| "We studied the effects of the calcium channel blocker, verapamil on experimental acute pancreatitis (AP) in rats." | 3.68 | [Effects of verapamil on prostacyclin, thromboxane and pancreatic blood flow of rats with experimental acute pancreatitis]. ( Shen, J, 1991) |
| " Animals in group 2 (n = 10) with artificially-induced pancreatitis received the same dosage of saline in the same manner." | 1.30 | Continuous calcium channel blocker infusion in experimentally induced acute pancreatitis: effects on pancreas and liver function. ( Ciner, I; Ciner, L; Soran, A; Yücel, E, 1998) |
| "Third, acute pancreatitis could be observed in rats with elevated serum calcium levels at low doses of cerulein (5 micrograms/kg/hr, subcutaneously), but could not be observed in rats with normal serum calcium levels treated with low doses of cerulein." | 1.29 | Evidence for altered cellular calcium in the pathogenetic mechanism of acute pancreatitis in rats. ( Han, Q; Miller, JE; Olson, MS; Shen, F; Zhou, W, 1996) |
| "Verapamil treatment decreased significantly tissue activity of trypsin (p less than 0." | 1.28 | [The effects of verapamil in experimental acute pancreatitis in the rat]. ( Díez Miralles, M; González Santos, J; Graells Ferrer, ML; Medrano Heredia, J; Pardo Correcher, JM; Regalado Pareja, RI; Ruiz Macía, JA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 8 (61.54) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, JW | 1 |
| Zhang, GX | 1 |
| Chen, HL | 1 |
| Liu, GL | 1 |
| Owusu, L | 1 |
| Wang, YX | 1 |
| Wang, GY | 1 |
| Xu, CM | 1 |
| Demin, LI | 1 |
| V'iushkov, DM | 1 |
| Minaev, II | 1 |
| Propp, AR | 1 |
| Zamorov, AG | 1 |
| Zhang, H | 1 |
| Li, YY | 1 |
| Lake-Bakaar, G | 1 |
| Lyubsky, S | 1 |
| Wang, XD | 1 |
| Deng, XM | 1 |
| Haraldsen, P | 1 |
| Andersson, R | 1 |
| Ihse, I | 1 |
| Zhou, W | 1 |
| Shen, F | 1 |
| Miller, JE | 1 |
| Han, Q | 1 |
| Olson, MS | 1 |
| Closa, D | 1 |
| Hotter, G | 1 |
| Bulbena, O | 1 |
| Gelpi, E | 1 |
| Rosello-Catafau, J | 1 |
| Wacke, R | 1 |
| Kirchner, A | 1 |
| Prall, F | 1 |
| Nizze, H | 1 |
| Schmidt, W | 1 |
| Fischer, U | 1 |
| Nitschke, FP | 1 |
| Adam, U | 1 |
| Fritz, P | 1 |
| Belloc, C | 1 |
| Drewelow, B | 1 |
| Soran, A | 1 |
| Yücel, E | 1 |
| Ciner, I | 1 |
| Ciner, L | 1 |
| Ueda, T | 1 |
| Takeyama, Y | 1 |
| Hori, Y | 1 |
| Takase, K | 1 |
| Goshima, M | 1 |
| Kuroda, Y | 1 |
| Regalado Pareja, RI | 1 |
| Pardo Correcher, JM | 1 |
| Díez Miralles, M | 1 |
| Graells Ferrer, ML | 1 |
| Ruiz Macía, JA | 1 |
| González Santos, J | 1 |
| Medrano Heredia, J | 1 |
| Shen, J | 1 |
| Zemskov, VS | 1 |
| Zhalko-Titarenko, Vf | 1 |
| Gol'dberg, AA | 1 |
1 trial available for verapamil and Pancreatitis
| Article | Year |
|---|---|
[Prophylactics of acute pancreatitis in pancreatic-duodenal resection].
Topics: Acute Disease; Antimetabolites; Aprotinin; Drug Administration Schedule; Duodenum; Fluorouracil; Hor | 2002 |
12 other studies available for verapamil and Pancreatitis
| Article | Year |
|---|---|
Therapeutic effect of Qingyi decoction in severe acute pancreatitis-induced intestinal barrier injury.
Topics: Acute Disease; Amine Oxidase (Copper-Containing); Amylases; Animals; Anti-Inflammatory Agents; Apopt | 2015 |
[Role of phospholipase A2 in injury of lung complicated by acute pancreatitis and the therapeutic effect and mechanism of verapamil on it].
Topics: Acute Disease; Animals; Female; Lung Injury; Male; Pancreatitis; Phospholipases A2; Rats; Rats, Spra | 2003 |
Dose-dependent effect of continuous subcutaneous verapamil infusion on experimental acute pancreatitis in mice.
Topics: Acute Disease; Animals; Calcium Channel Blockers; Choline; Cytoplasmic Granules; Dose-Response Relat | 1995 |
Antioxidant and calcium channel blockers counteract endothelial barrier injury induced by acute pancreatitis in rats.
Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Calcium; Calcium Channel Blockers; Diltiazem; | 1995 |
Evidence for altered cellular calcium in the pathogenetic mechanism of acute pancreatitis in rats.
Topics: Acute Disease; Animals; Calcium; Calcium Channel Blockers; Ceruletide; Drug Synergism; Male; Pancrea | 1996 |
Calcium channel blockers in experimental acute pancreatitis: effect on tissue prostanoids and oxygen free radicals.
Topics: Acute Disease; Animals; Calcium Channel Blockers; Dinoprostone; Free Radicals; Male; Oxygen; Pancrea | 1996 |
Up-regulation of cytochrome P450 1A2, 2C9, and 2E1 in chronic pancreatitis.
Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Chronic Disease; Cytochrome P-450 CYP1A2; Cytochrome P-4 | 1998 |
Continuous calcium channel blocker infusion in experimentally induced acute pancreatitis: effects on pancreas and liver function.
Topics: Acute Disease; Animals; Calcium Channel Blockers; Infusions, Intravenous; Liver; Pancreas; Pancreati | 1998 |
Pancreatitis-associated ascitic fluid increases intracellular Ca(2+) concentration on hepatocytes.
Topics: Acute Disease; Animals; Ascitic Fluid; Calcium; Cells, Cultured; Dogs; Egtazic Acid; Liver; Male; Mu | 2000 |
[The effects of verapamil in experimental acute pancreatitis in the rat].
Topics: Acute Disease; Animals; Drug Evaluation, Preclinical; Female; Male; Pancreas; Pancreatitis; Rats; Ra | 1992 |
[Effects of verapamil on prostacyclin, thromboxane and pancreatic blood flow of rats with experimental acute pancreatitis].
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Female; Male; Pancreas; Pancreatitis; Rats; Ra | 1991 |
[Verapamil in the combined therapy of acute pancreatitis].
Topics: Acute Disease; Adult; Humans; Male; Pancreatitis; Verapamil | 1985 |