verapamil has been researched along with Pain in 44 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven patients, comprising three cases of McArdle's disease and eight with an exertional muscle pain syndrome (EMPS) of unknown cause, entered a double-blind crossover study of verapamil and placebo." | 9.06 | A double-blind, placebo-controlled, crossover study of verapamil in exertional muscle pain. ( Lane, RJ; Turnbull, DM; Walton, J; Welch, JL, 1986) |
| "To assess the effects of verapamil and nifedipine on left ventricular function at rest and during exercise in patients with Prinzmetal's variant angina pectoris, 10 patients (6 men and 4 women with a mean age of 52 years) with variant angina were each treated for 2 months periods with placebo, verapamil (400 +/- 80 mg/day, mean +/- standard deviation [SD]) and nifedipine (82 +/- 31 mg/day)." | 9.05 | Effect of verapamil and nifedipine on left ventricular function at rest and during exercise in patients with Prinzmetal's variant angina pectoris. ( Corbett, J; Dehmer, GJ; Hillis, LD; Johnson, SM; Lewis, SE; Mauritson, DR; Willerson, JT, 1981) |
| "Thirty-one patients with 43 keloids were treated with IL verapamil at 3-week intervals until reaching complete flattening of the lesion or for a maximum of 6 sessions." | 8.02 | Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study. ( Abou-Taleb, DAE; Badary, DM, 2021) |
| "Hydrogen sulfide (H(2) S), generated by enzymes such as cystathionine-γ-lyase (CSE) from L-cysteine, facilitates pain signals by activating the Ca(v) 3." | 7.78 | Involvement of the endogenous hydrogen sulfide/Ca(v) 3.2 T-type Ca2+ channel pathway in cystitis-related bladder pain in mice. ( Hayashi, Y; Kawabata, A; Kubo, L; Matsunami, M; Miki, T; Nishikawa, H; Nishiura, K; Okawa, Y; Ozaki, T; Sekiguchi, F; Tsujiuchi, T, 2012) |
| "These results suggest that by lowering capsaicin-induced neural activity in nociceptive terminals, diltiazem decreases pain and neurogenic inflammation and may be useful as both an analgesic and an antiinflammatory agent in the eye." | 7.68 | Reduction of capsaicin-induced ocular pain and neurogenic inflammation by calcium antagonists. ( Belmonte, C; Gallar, J; Garcia de la Rubia, P; Gonzalez, GG, 1993) |
| "The effect of daily verapamil administration (5 mg/kg) on pain sensitivity, bioelectric activity of cerebral cortex and microcirculation was studied in rats with cut sciatic nerve." | 7.68 | [Effects of verapamil on the development of pain syndrome in rats after section of the sciatic nerve]. ( Gorizontova, MP; Kryzhanovskiĭ, GN; Kukushkin, ML; Reshetniak, VK; Smirnova, VS, 1992) |
| "In the experiments on Wistar rats with pain syndrome of spinal origin (PSSO) caused by the generator of pathologically enhanced excitation (GPEE) in dorsal horns of the spinal cord lumbosacral segments, it was shown that the intravenous verapamil injection (1." | 7.68 | [Effects of verapamil on behavioral and microcirculatory disorders in pain syndrome of spinal etiology]. ( Gorizontova, MP; Igon'kina, SI; Kryzhanovskiĭ, GI; Speranskaia, TV, 1990) |
| "This study demonstrates that magnesium is a more effective vasodilator when compared to verapamil, with a reduced hemodynamic effect, and is equally effective at preventing radial artery spasm." | 5.13 | Magnesium sulphate during transradial cardiac catheterization: a new use for an old drug? ( Byrne, J; Della Siega, A; Fretz, E; Haegeli, L; Hilton, D; Kinloch, D; Klinke, P; Mildenberger, R; Spence, M; Williams, M, 2008) |
| "Three calcium (Ca) channel antagonists were administered to healthy adult volunteers by iontophoresis alone or in combination with lidocaine to study their effects on the pain threshold." | 5.08 | The effect of calcium channel antagonist administered by iontophoresis on the pain threshold. ( Honda, N; Miyagawa, A; Mizutani, A; Oyama, T; Taniguchi, K, 1995) |
| "Eleven patients, comprising three cases of McArdle's disease and eight with an exertional muscle pain syndrome (EMPS) of unknown cause, entered a double-blind crossover study of verapamil and placebo." | 5.06 | A double-blind, placebo-controlled, crossover study of verapamil in exertional muscle pain. ( Lane, RJ; Turnbull, DM; Walton, J; Welch, JL, 1986) |
| "To assess the effects of verapamil and nifedipine on left ventricular function at rest and during exercise in patients with Prinzmetal's variant angina pectoris, 10 patients (6 men and 4 women with a mean age of 52 years) with variant angina were each treated for 2 months periods with placebo, verapamil (400 +/- 80 mg/day, mean +/- standard deviation [SD]) and nifedipine (82 +/- 31 mg/day)." | 5.05 | Effect of verapamil and nifedipine on left ventricular function at rest and during exercise in patients with Prinzmetal's variant angina pectoris. ( Corbett, J; Dehmer, GJ; Hillis, LD; Johnson, SM; Lewis, SE; Mauritson, DR; Willerson, JT, 1981) |
| " Naloxone, a relatively pure opiate antagonist, was an additional test administered to 6 volunteer patients who had experienced an alleviation of pain with TENS." | 5.05 | Relief of primary dysmenorrhea by transcutaneous electrical nerve stimulation. ( Bondesson, L; Lundeberg, T; Lundström, V, 1985) |
| "Thirty-one patients with 43 keloids were treated with IL verapamil at 3-week intervals until reaching complete flattening of the lesion or for a maximum of 6 sessions." | 4.02 | Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study. ( Abou-Taleb, DAE; Badary, DM, 2021) |
| "Hydrogen sulfide (H(2) S), generated by enzymes such as cystathionine-γ-lyase (CSE) from L-cysteine, facilitates pain signals by activating the Ca(v) 3." | 3.78 | Involvement of the endogenous hydrogen sulfide/Ca(v) 3.2 T-type Ca2+ channel pathway in cystitis-related bladder pain in mice. ( Hayashi, Y; Kawabata, A; Kubo, L; Matsunami, M; Miki, T; Nishikawa, H; Nishiura, K; Okawa, Y; Ozaki, T; Sekiguchi, F; Tsujiuchi, T, 2012) |
| "Verapamil and dexamethasone iontophoresis is a safe and reliable treatment resolving painful erections in the acute phase of PD." | 3.78 | Transdermal iontophoresis with verapamil and dexamethasone in the acute phase of peyronie's disease. Our experience. ( Coloma, A; Fernández Arjona, M; Formoso, T; Garrido Abad, P; Herranz, LM; Jiménez, M; Prieto, MD; Suárez, C, 2012) |
| "A 20-year-old female with hemiplegic migraine was treated during an acute attack with intravenous verapamil, which reproducibly resolved the headache within 20 min but did not affect her hemiplegia." | 3.74 | Hemiplegic migraine: hyperperfusion and abortive therapy with intravenous verapamil. ( Dulli, DA; Hsu, DA; Kiff, JE; Rowley, HA; Stafstrom, CE, 2008) |
| "To evaluate the effects of the transdermal electromotive administration of verapamil and dexamethasone on plaque size, penile deviation, pain, erectile function and capacity for vaginal penetration in patients with Peyronie's disease." | 3.72 | Transdermal electromotive administration of verapamil and dexamethasone for Peyronie's disease. ( Capelli, G; Di Stasi, SM; Giannantoni, A; Jannini, EA; Storti, L; Vespasiani, G; Virgili, G, 2003) |
| "By applying a 12 day regimen of the non-calorific sweetener, aspartame, in combination with representative compounds of the calcium channel blocker and nitric oxide synthase inhibitor, we tried to investigate using a formalin-test in mice the relative role of aspartame on pain and its mechanism of action." | 3.71 | Potentiation by nitric oxide synthase inhibitor and calcium channel blocker of aspartame-induced antinociception in the mouse formalin test. ( Abdoli, N; Abdollahi, M; Nikfar, S, 2001) |
| "These results suggest that by lowering capsaicin-induced neural activity in nociceptive terminals, diltiazem decreases pain and neurogenic inflammation and may be useful as both an analgesic and an antiinflammatory agent in the eye." | 3.68 | Reduction of capsaicin-induced ocular pain and neurogenic inflammation by calcium antagonists. ( Belmonte, C; Gallar, J; Garcia de la Rubia, P; Gonzalez, GG, 1993) |
| "The effect of daily verapamil administration (5 mg/kg) on pain sensitivity, bioelectric activity of cerebral cortex and microcirculation was studied in rats with cut sciatic nerve." | 3.68 | [Effects of verapamil on the development of pain syndrome in rats after section of the sciatic nerve]. ( Gorizontova, MP; Kryzhanovskiĭ, GN; Kukushkin, ML; Reshetniak, VK; Smirnova, VS, 1992) |
| "In the experiments on Wistar rats with pain syndrome of spinal origin (PSSO) caused by the generator of pathologically enhanced excitation (GPEE) in dorsal horns of the spinal cord lumbosacral segments, it was shown that the intravenous verapamil injection (1." | 3.68 | [Effects of verapamil on behavioral and microcirculatory disorders in pain syndrome of spinal etiology]. ( Gorizontova, MP; Igon'kina, SI; Kryzhanovskiĭ, GI; Speranskaia, TV, 1990) |
| "The effects of the calcium channel antagonists diltiazem, nifedipine and verapamil and the calcium channel agonist, BAY K 8644, on offensive and defensive aggression and defeat-induced opioid analgesia were examined in male mice in resident-intruder interactions." | 3.67 | Aggression and defeat-induced opioid analgesia displayed by mice are modified by calcium channel antagonists and agonists. ( Kavaliers, M, 1987) |
| "Peyronie's disease is a condition that results in the development of penile plaques that can lead to penile curvature, pain, and erectile dysfunction, making sexual activity difficult." | 3.01 | Non-surgical therapies for Peyronie's disease. ( Blair, Y; Dahm, P; Edwards, ME; Ergun, O; Hwang, EC; Jung, JH; Risk, MC; Rosenberg, JE, 2023) |
| "Different approaches are used aiming to improve these scars, including intralesional corticosteroids, surgery and more recently, laser therapy." | 2.82 | Laser therapy for treating hypertrophic and keloid scars. ( da Silva, CA; da Silva, EM; Kuczynski, U; Leszczynski, R; Pinto, ACPN, 2022) |
| "Radial artery spasm is a frequent complication of the transradial approach for coronary angiography and angioplasty." | 1.32 | Evaluation of a spasmolytic cocktail to prevent radial artery spasm during coronary procedures. ( Eccleshall, SC; Kiemeneij, F; Laarman, G; Slagboom, T; Vajifdar, BU; van der Wieken, R, 2003) |
| "Pretreatment with nimodipine (40 mg/kg) did not affect the morphine level in the brain and also decreased the brain-to-serum ratio of morphine." | 1.32 | Role of pharmacokinetic effects in the potentiation of morphine analgesia by L-type calcium channel blockers in mice. ( Fukazawa, Y; Kishioka, S; Maeda, T; Ozaki, M; Shimizu, N; Yamamoto, C; Yamamoto, H, 2004) |
| "7 nmol), the log dose-response relationship being shifted to left by pretreatment with 5 mg/kg i." | 1.29 | Calcium channel modulators modify K opioid-induced inhibition of C-fiber-evoked spinal reflexes in rat. ( Contreras, E; Hernández, A; Paeile, C; Pelissier, T; Pérez, H; Quijada, L; Soto-Moyano, R, 1993) |
| "Verapamil was administered i." | 1.25 | [Venous infusion of nerapamil in the treatment of refractory angina pectoris and arrhythmia due to associated electric instability]. ( Furlanello, F; Lanzetta, T; Pascotto, P; Piccolo, E; Trevi, GP, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (38.64) | 18.7374 |
| 1990's | 10 (22.73) | 18.2507 |
| 2000's | 10 (22.73) | 29.6817 |
| 2010's | 3 (6.82) | 24.3611 |
| 2020's | 4 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Stefanucci, A | 1 |
| Dimmito, MP | 1 |
| Macedonio, G | 1 |
| Ciarlo, L | 1 |
| Pieretti, S | 1 |
| Novellino, E | 1 |
| Lei, W | 1 |
| Barlow, D | 1 |
| Houseknecht, KL | 1 |
| Streicher, JM | 1 |
| Mollica, A | 1 |
| Leszczynski, R | 1 |
| da Silva, CA | 1 |
| Pinto, ACPN | 1 |
| Kuczynski, U | 1 |
| da Silva, EM | 1 |
| Rosenberg, JE | 1 |
| Ergun, O | 1 |
| Hwang, EC | 1 |
| Risk, MC | 1 |
| Jung, JH | 1 |
| Edwards, ME | 1 |
| Blair, Y | 1 |
| Dahm, P | 1 |
| Abou-Taleb, DAE | 1 |
| Badary, DM | 1 |
| Alizadeh, M | 1 |
| Karimi, F | 1 |
| Fallah, MR | 1 |
| Zellner, C | 1 |
| Boyle, A | 1 |
| Yeghiazarians, Y | 1 |
| Byrne, J | 1 |
| Spence, M | 1 |
| Haegeli, L | 1 |
| Fretz, E | 1 |
| Della Siega, A | 1 |
| Williams, M | 1 |
| Kinloch, D | 1 |
| Mildenberger, R | 1 |
| Klinke, P | 1 |
| Hilton, D | 1 |
| Matsunami, M | 1 |
| Miki, T | 1 |
| Nishiura, K | 1 |
| Hayashi, Y | 1 |
| Okawa, Y | 1 |
| Nishikawa, H | 1 |
| Sekiguchi, F | 1 |
| Kubo, L | 1 |
| Ozaki, T | 1 |
| Tsujiuchi, T | 1 |
| Kawabata, A | 1 |
| Garrido Abad, P | 1 |
| Coloma, A | 1 |
| Herranz, LM | 1 |
| Jiménez, M | 1 |
| Suárez, C | 1 |
| Prieto, MD | 1 |
| Formoso, T | 1 |
| Fernández Arjona, M | 1 |
| Kiemeneij, F | 1 |
| Vajifdar, BU | 1 |
| Eccleshall, SC | 1 |
| Laarman, G | 1 |
| Slagboom, T | 1 |
| van der Wieken, R | 1 |
| Di Stasi, SM | 1 |
| Giannantoni, A | 1 |
| Capelli, G | 1 |
| Jannini, EA | 1 |
| Virgili, G | 1 |
| Storti, L | 1 |
| Vespasiani, G | 1 |
| Shimizu, N | 1 |
| Kishioka, S | 1 |
| Maeda, T | 1 |
| Fukazawa, Y | 1 |
| Yamamoto, C | 1 |
| Ozaki, M | 1 |
| Yamamoto, H | 1 |
| Hsu, DA | 1 |
| Stafstrom, CE | 1 |
| Rowley, HA | 1 |
| Kiff, JE | 1 |
| Dulli, DA | 1 |
| Juan, H | 1 |
| Seewann, S | 1 |
| Walton, J | 2 |
| Schwartz, JB | 1 |
| Jeang, M | 1 |
| Raizner, AE | 1 |
| Griffin, JC | 1 |
| Wyndham, CR | 1 |
| Johnson, SM | 1 |
| Mauritson, DR | 1 |
| Corbett, J | 1 |
| Dehmer, GJ | 1 |
| Lewis, SE | 1 |
| Willerson, JT | 1 |
| Hillis, LD | 1 |
| Moraes, NL | 1 |
| Fiorelli, AI | 1 |
| Ribeiro, LF | 1 |
| Gomes, OM | 1 |
| Hernández, A | 1 |
| Contreras, E | 1 |
| Paeile, C | 1 |
| Pérez, H | 1 |
| Pelissier, T | 1 |
| Quijada, L | 1 |
| Soto-Moyano, R | 1 |
| Nagahisa, A | 1 |
| Asai, R | 1 |
| Kanai, Y | 1 |
| Murase, A | 1 |
| Tsuchiya-Nakagaki, M | 1 |
| Nakagaki, T | 1 |
| Shieh, TC | 1 |
| Taniguchi, K | 2 |
| Gonzalez, GG | 1 |
| Garcia de la Rubia, P | 1 |
| Gallar, J | 1 |
| Belmonte, C | 1 |
| Miyagawa, A | 1 |
| Mizutani, A | 1 |
| Honda, N | 1 |
| Oyama, T | 1 |
| Hodoğluğil, U | 1 |
| Güney, HZ | 1 |
| Savran, B | 1 |
| Güzey, C | 1 |
| Görgün, CZ | 1 |
| Zengil, H | 1 |
| Switzer, DS | 1 |
| Horváth, G | 1 |
| Brodacz, B | 1 |
| Holzer-Petsche, U | 1 |
| Assi, AA | 1 |
| Abdollahi, M | 1 |
| Nikfar, S | 1 |
| Abdoli, N | 1 |
| Just, S | 1 |
| Leipold-Büttner, C | 1 |
| Heppelmann, B | 1 |
| Escojido, H | 1 |
| Boyer, C | 1 |
| Mourot, F | 1 |
| Bonello, R | 1 |
| Jouve, A | 1 |
| Piccolo, E | 1 |
| Furlanello, F | 1 |
| Trevi, GP | 1 |
| Pascotto, P | 1 |
| Lanzetta, T | 1 |
| Kryzhanovskiĭ, GN | 1 |
| Reshetniak, VK | 1 |
| Kukushkin, ML | 1 |
| Gorizontova, MP | 2 |
| Smirnova, VS | 1 |
| Gürdal, H | 1 |
| Sara, Y | 1 |
| Tulunay, FC | 1 |
| al-Humayyd, MS | 1 |
| Kryzhanovskiĭ, GI | 1 |
| Igon'kina, SI | 1 |
| Speranskaia, TV | 1 |
| Kavaliers, M | 3 |
| Geng, WP | 1 |
| Xu, SY | 1 |
| Lane, RJ | 1 |
| Turnbull, DM | 1 |
| Welch, JL | 1 |
| Archer, CB | 1 |
| Greaves, MW | 1 |
| Lundeberg, T | 1 |
| Bondesson, L | 1 |
| Lundström, V | 1 |
| Weidinger, H | 1 |
| Wiest, W | 1 |
| Kipsidze, NN | 1 |
| Capidze, GJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Kinesiotaping With and Without Pelvic Tilts on Pain and Menstrual Distress in Females With Dysmenorrhea[NCT05355194] | 30 participants (Actual) | Interventional | 2022-04-20 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for verapamil and Pain
| Article | Year |
|---|---|
Laser therapy for treating hypertrophic and keloid scars.
Topics: Adrenal Cortex Hormones; Adult; Aluminum; Atrophy; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Di | 2022 |
Non-surgical therapies for Peyronie's disease.
Topics: Erectile Dysfunction; Humans; Male; Pain; Penile Induration; Quality of Life; Randomized Controlled | 2023 |
7 trials available for verapamil and Pain
| Article | Year |
|---|---|
Evaluation of verapamil efficacy in Peyronie's disease comparing with pentoxifylline.
Topics: Adult; Aged; Drug Therapy, Combination; Erectile Dysfunction; Humans; Iran; Male; Middle Aged; Pain; | 2014 |
Magnesium sulphate during transradial cardiac catheterization: a new use for an old drug?
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Cardiac Catheterization; Coronary Angiography; Double-Bl | 2008 |
Effect of verapamil and nifedipine on left ventricular function at rest and during exercise in patients with Prinzmetal's variant angina pectoris.
Topics: Angina Pectoris; Angina Pectoris, Variant; Exercise Test; Female; Heart Ventricles; Hemodynamics; Hu | 1981 |
The effect of calcium channel antagonist administered by iontophoresis on the pain threshold.
Topics: Adult; Calcium Channel Blockers; Diltiazem; Drug Combinations; Female; Humans; Iontophoresis; Lidoca | 1995 |
A double-blind, placebo-controlled, crossover study of verapamil in exertional muscle pain.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Glycogen Storage Disease; Glycogen Sto | 1986 |
Relief of primary dysmenorrhea by transcutaneous electrical nerve stimulation.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dysmenorrhea; Electric Stimulation Therapy; Female; Hum | 1985 |
[The effectiveness of treating patients with coronary insufficiency with verapamil].
Topics: Acid-Base Equilibrium; Adult; Aged; Anti-Arrhythmia Agents; Blood Circulation; Blood Flow Velocity; | 1970 |
35 other studies available for verapamil and Pain
| Article | Year |
|---|---|
Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration.
Topics: Administration, Intravenous; Analgesics, Opioid; Animals; CHO Cells; Cricetulus; Female; Humans; Inf | 2020 |
Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study.
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Pain; Treatment Outcome; Verapamil | 2021 |
Magnesium sulfate for transradial cardiac catheterization: teaching an old dog new tricks.
Topics: Analgesics; Cardiac Catheterization; Coronary Angiography; Hemodynamics; Humans; Magnesium Sulfate; | 2008 |
Involvement of the endogenous hydrogen sulfide/Ca(v) 3.2 T-type Ca2+ channel pathway in cystitis-related bladder pain in mice.
Topics: Acetanilides; Animals; Benzimidazoles; Calcium Channel Blockers; Calcium Channels, T-Type; Cyclophos | 2012 |
Transdermal iontophoresis with verapamil and dexamethasone in the acute phase of peyronie's disease. Our experience.
Topics: Administration, Cutaneous; Adult; Aged; Anti-Inflammatory Agents; Calcium Channel Blockers; Coitus; | 2012 |
Evaluation of a spasmolytic cocktail to prevent radial artery spasm during coronary procedures.
Topics: Aged; Angina Pectoris; Angioplasty; Coronary Angiography; Drug Therapy, Combination; Female; Humans; | 2003 |
Transdermal electromotive administration of verapamil and dexamethasone for Peyronie's disease.
Topics: Administration, Cutaneous; Adult; Aged; Dexamethasone; Drug Combinations; Erectile Dysfunction; Huma | 2003 |
Role of pharmacokinetic effects in the potentiation of morphine analgesia by L-type calcium channel blockers in mice.
Topics: Analgesia; Animals; Area Under Curve; Brain; Brain Chemistry; Calcium Channel Blockers; Calcium Chan | 2004 |
Hemiplegic migraine: hyperperfusion and abortive therapy with intravenous verapamil.
Topics: Adult; Brain; Cerebral Angiography; Cerebral Arteries; Cerebrovascular Circulation; Cerebrovascular | 2008 |
Selective reduction by some vasodilators and the prostaglandin antagonist SC-19220 of a response to the algesic effect of bradykinin.
Topics: Acetylcholine; Aminophylline; Animals; Bradykinin; Depression, Chemical; Dibenz(b,f)(1,4)oxazepine-1 | 1980 |
Diffuse exercise-induced muscle pain of undetermined cause relieved by verapamil.
Topics: Adult; Female; Humans; Male; Muscular Diseases; Pain; Physical Exertion; Verapamil | 1981 |
Accelerated junctional rhythms during oral verapamil therapy.
Topics: Administration, Oral; Arrhythmias, Cardiac; Electrocardiography; Female; Heart Block; Humans; Male; | 1984 |
[Use of verapamil in the treatment of pain in acute myocardial infarction].
Topics: Adult; Aged; Angina Pectoris; Female; Hemodynamics; Humans; Infusions, Parenteral; Male; Middle Aged | 1981 |
Calcium channel modulators modify K opioid-induced inhibition of C-fiber-evoked spinal reflexes in rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Non-specific activity of (+/-)CP-96,345 in models of pain and inflammation.
Topics: Animals; Biphenyl Compounds; Carrageenan; Dose-Response Relationship, Drug; Edema; Hyperalgesia; Hyp | 1993 |
Reduction of capsaicin-induced ocular pain and neurogenic inflammation by calcium antagonists.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Capsaicin; Cornea; Dilti | 1993 |
Temporal variation in the interaction between calcium channel blockers and morphine-induced analgesia.
Topics: Analgesia; Animals; Calcium Channel Blockers; Circadian Rhythm; Diltiazem; Drug Synergism; Male; Mic | 1996 |
Effect of verapamil in intermittent claudication.
Topics: Aged; Delayed-Action Preparations; Humans; Intermittent Claudication; Middle Aged; Pain; Randomized | 1997 |
Role of calcium channels in the spinal transmission of nociceptive information from the mesentery.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2001 |
The influence of divalent cations on the analgesic effect of opioid and non-opioid drugs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Blood Pressure; Butorphanol; C | 2001 |
Potentiation by nitric oxide synthase inhibitor and calcium channel blocker of aspartame-induced antinociception in the mouse formalin test.
Topics: Analgesics; Animals; Aspartame; Calcium Channel Blockers; Drug Synergism; Enzyme Inhibitors; Male; M | 2001 |
Histological demonstration of voltage dependent calcium channels on calcitonin gene-related peptide-immunoreactive nerve fibres in the mouse knee joint.
Topics: Animals; Binding Sites; Calcitonin Gene-Related Peptide; Calcium Channels; Calcium Channels, L-Type; | 2001 |
Verapamil.
Topics: Adult; Female; Humans; Joint Diseases; Middle Aged; Pain; Urticaria; Verapamil | 1979 |
[Treatment of painful forms of mitral valve prolapse with verapamil].
Topics: Adult; Female; Humans; Male; Middle Aged; Mitral Valve Prolapse; Pain; Verapamil | 1978 |
[Venous infusion of nerapamil in the treatment of refractory angina pectoris and arrhythmia due to associated electric instability].
Topics: Adult; Angina Pectoris; Angiography; Arrhythmias, Cardiac; Atrial Fibrillation; Coronary Angiography | 1975 |
[Effects of verapamil on the development of pain syndrome in rats after section of the sciatic nerve].
Topics: Animals; Evoked Potentials; Male; Microcirculation; Pain; Rats; Rats, Wistar; Sciatic Nerve; Somatos | 1992 |
Effects of calcium channel blockers on formalin-induced nociception and inflammation in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Diltiazem; F | 1992 |
Effect of diltiazem, nifedipine and verapamil on the antinociceptive action of acetylsalicylic acid in mice.
Topics: Analgesics; Animals; Aspirin; Benzoquinones; Diltiazem; Drug Interactions; Male; Mice; Nifedipine; P | 1991 |
[Effects of verapamil on behavioral and microcirculatory disorders in pain syndrome of spinal etiology].
Topics: Animals; Behavior, Animal; Dipyrone; Male; Microcirculation; Pain; Rats; Rats, Inbred Strains; Spina | 1990 |
Aggression and defeat-induced opioid analgesia displayed by mice are modified by calcium channel antagonists and agonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1987 |
Stimulatory influences of calcium channel antagonists on stress-induced opioid analgesia and locomotor activity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1987 |
Calcium channel blockers inhibit the antagonistic effects of Phe-Met-Arg-Phe-amide (FMRFamide) on morphine- and stress-induced analgesia in mice.
Topics: Animals; Calcium; Drug Interactions; FMRFamide; Ion Channels; Mice; Morphine; Nervous System; Neurop | 1987 |
[Relationship between clonidine analgesia and the calcium cation].
Topics: Analgesics; Animals; Calcium Chloride; Clonidine; Egtazic Acid; Male; Pain; Radioligand Assay; Rats; | 1987 |
Assessment of treatment for painful cutaneous leiomyomas.
Topics: Adult; Humans; Leiomyoma; Male; Nifedipine; Pain; Pain Measurement; Phenoxybenzamine; Skin Neoplasms | 1987 |
[The treatment of late abortion and of threatened premature birth with Th 1165 a combined with Isoptin (author's transl)].
Topics: Abortion, Spontaneous; Adrenergic beta-Agonists; Calcium; Drug Therapy, Combination; Female; Gestati | 1973 |