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verapamil and Nervous System Diseases

verapamil has been researched along with Nervous System Diseases in 10 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.

Research Excerpts

ExcerptRelevanceReference
"The nifedipine response was reproduced by isradipine and by verapamil with IC50 values of 9 and 100 nM, respectively."1.28Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity. ( Memo, M; Pizzi, M; Ribola, M; Spano, P; Valerio, A, 1991)
" The mean nontoxic dose was 320 mg, whereas the mean toxic ingestion was 3."1.28Calcium channel blocker toxicity. ( Myers, A; Ramoska, EA; Spiller, HA, 1990)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's4 (40.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kubo, Y1
Balayssac, D1
Cayre, A1
Ling, B1
Maublant, J1
Penault-Llorca, F1
Eschalier, A1
Coudore, F1
Authier, N1
Marsh, E1
O'Callaghan, P1
Smith, P1
Fossati, C1
Guistiniani, S1
van Poeck, KJ1
Pizzi, M1
Ribola, M1
Valerio, A1
Memo, M1
Spano, P1
Wright, BA1
Jarrett, DB1
Ramoska, EA1
Spiller, HA1
Myers, A1
Price, WA2
DiMarzio, LR1
Giannini, AJ1

Reviews

3 reviews available for verapamil and Nervous System Diseases

ArticleYear
[Carrier-mediated Transport of Cationic Drugs across the Blood-Tissue Barrier].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2015, Volume: 135, Issue:10

    Topics: Angiogenesis Inhibitors; Biological Transport; Blood-Brain Barrier; Blood-Retinal Barrier; Cation Tr

2015
The humble electrocardiogram.
    Practical neurology, 2008, Volume: 8, Issue:1

    Topics: Anticonvulsants; Arrhythmias, Cardiac; Brain Diseases; Electrocardiography; Heart; Humans; Nervous S

2008
[Side-effects of calcium antagonists].
    La Clinica terapeutica, 1984, Jun-30, Volume: 109, Issue:6

    Topics: Calcium Channel Blockers; Cardiovascular Diseases; Drug Hypersensitivity; Drug Interactions; Fendili

1984

Other Studies

7 other studies available for verapamil and Nervous System Diseases

ArticleYear
Vincristine-induced neuropathy in the rat is not modified by drug-drug interactions with the P-glycoprotein inhibitor verapamil.
    Chemotherapy, 2008, Volume: 54, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Weight; Drug Interactions; Ma

2008
[Chronic recurrent headache without neurological abnormalities. Practice guidelines of the Netherlands Society of Neurology].
    Nederlands tijdschrift voor geneeskunde, 1999, Jun-05, Volume: 143, Issue:23

    Topics: Adult; Aged; Chronic Disease; Contraindications; Drug Interactions; Female; Guidelines as Topic; Hea

1999
Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity.
    European journal of pharmacology, 1991, Dec-17, Volume: 209, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Lithium and calcium channel blockers: possible neurotoxicity.
    Biological psychiatry, 1991, Sep-15, Volume: 30, Issue:6

    Topics: Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Hypertension; Lithium Carbonate; Middle

1991
Calcium channel blocker toxicity.
    Annals of emergency medicine, 1990, Volume: 19, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Child; Child, Preschool; Delaware;

1990
Verapamil-carbamazepine neurotoxicity.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:2

    Topics: Bipolar Disorder; Carbamazepine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Middle A

1988
Lithium-verapamil: further considerations.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:3

    Topics: Drug Synergism; Humans; Lithium; Nervous System; Nervous System Diseases; Verapamil

1987