verapamil has been researched along with Nerve Degeneration in 6 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The nifedipine response was reproduced by isradipine and by verapamil with IC50 values of 9 and 100 nM, respectively." | 1.28 | Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity. ( Memo, M; Pizzi, M; Ribola, M; Spano, P; Valerio, A, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Jangholi, E | 1 |
| Sharifi, ZN | 1 |
| Hoseinian, M | 1 |
| Zarrindast, MR | 1 |
| Rahimi, HR | 1 |
| Mowla, A | 1 |
| Aryan, H | 1 |
| Javidi, MA | 1 |
| Parsa, Y | 1 |
| Ghaffarpasand, F | 1 |
| Yadollah-Damavandi, S | 1 |
| Arani, HZ | 1 |
| Shahi, F | 1 |
| Movassaghi, S | 1 |
| Yadav, S | 1 |
| Tapadia, MG | 1 |
| Vallazza-Deschamps, G | 1 |
| Cia, D | 1 |
| Gong, J | 1 |
| Jellali, A | 1 |
| Duboc, A | 1 |
| Forster, V | 1 |
| Sahel, JA | 1 |
| Tessier, LH | 1 |
| Picaud, S | 1 |
| Zhu, L | 1 |
| Gao, J | 1 |
| Wang, Y | 1 |
| Zhao, XN | 1 |
| Zhang, ZX | 1 |
| Ciani, E | 1 |
| Baldinotti, I | 1 |
| Contestabile, A | 1 |
| Pizzi, M | 1 |
| Ribola, M | 1 |
| Valerio, A | 1 |
| Memo, M | 1 |
| Spano, P | 1 |
6 other studies available for verapamil and Nerve Degeneration
| Article | Year |
|---|---|
Verapamil Inhibits Mitochondria-Induced Reactive Oxygen Species and Dependent Apoptosis Pathways in Cerebral Transient Global Ischemia/Reperfusion.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Brain; Caspase 3; Cell Survival; Cytochrom | 2020 |
Neurodegeneration caused by polyglutamine expansion is regulated by P-glycoprotein in Drosophila melanogaster.
Topics: Animals; Animals, Genetically Modified; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dro | 2013 |
Excessive activation of cyclic nucleotide-gated channels contributes to neuronal degeneration of photoreceptors.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Blotting, Western; Cadmium Chloride; Calcium | 2005 |
Neuron degeneration induced by verapamil and attenuated by EGb761.
Topics: Animals; Apoptosis; Axons; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Cerebral Cortex | 1997 |
Sustained, long-lasting inhibition of nitric oxide synthase aggravates the neural damage in some models of excitotoxic brain injury.
Topics: Animals; Basal Nucleus of Meynert; Brain; Brain Injuries; Calcium Channel Blockers; Choline O-Acetyl | 2001 |
Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |