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verapamil and Myasthenia Gravis

verapamil has been researched along with Myasthenia Gravis in 6 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

Research Excerpts

ExcerptRelevanceReference
"The effects of intravenous verapamil (18 micrograms, 36 micrograms, 72 micrograms kg-1) on neuromuscular transmission were studied in the integrated electromyographic (IEMG) responses of indirectly stimulated thenar muscles of five myasthenia gravis patients and 12 other patients without neuromuscular diseases anesthetized with thiopentone, pethidine and nitrous oxide in oxygen."7.67Acute effects of verapamil on neuromuscular transmission in patients with myasthenia gravis. ( Ho, ST; Lee, SC, 1987)
"The effects of intravenous verapamil (18 micrograms, 36 micrograms, 72 micrograms kg-1) on neuromuscular transmission were studied in the integrated electromyographic (IEMG) responses of indirectly stimulated thenar muscles of five myasthenia gravis patients and 12 other patients without neuromuscular diseases anesthetized with thiopentone, pethidine and nitrous oxide in oxygen."3.67Acute effects of verapamil on neuromuscular transmission in patients with myasthenia gravis. ( Ho, ST; Lee, SC, 1987)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wirguin, I1
Brenner, T1
Sicsic, C1
Argov, Z1
Reverte, M1
Matell, G1
Bjelak, S1
Jonkers, I1
Pirskanen, R1
Van Vliet, J1
Swerup, C1
Swash, M1
Ingram, DA1
Casado, I1
Nevado, L1
Dorrego, FG1
Lee, SC1
Ho, ST1

Other Studies

6 other studies available for verapamil and Myasthenia Gravis

ArticleYear
Variable effect of calcium channel blockers on the decremental response in experimental autoimmune myasthenia gravis.
    Muscle & nerve, 1994, Volume: 17, Issue:5

    Topics: Action Potentials; Animals; Electric Stimulation; Muscles; Myasthenia Gravis; Nimodipine; Rabbits; T

1994
Adverse effect of verapamil in myasthenia gravis: an additional comment.
    Muscle & nerve, 1993, Volume: 16, Issue:8

    Topics: Humans; Hypokalemia; Myasthenia Gravis; Verapamil

1993
Calcium channel and beta-receptor antagonists and agonists in MG.
    Annals of the New York Academy of Sciences, 1998, May-13, Volume: 841

    Topics: Administration, Oral; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Calcium Channel Blocker

1998
Adverse effect of verapamil in myasthenia gravis.
    Muscle & nerve, 1992, Volume: 15, Issue:3

    Topics: Contraindications; Coronary Artery Bypass; Coronary Disease; Electromyography; Humans; Male; Middle

1992
[Myasthenia associated with verapamil].
    Revista clinica espanola, 1989, Volume: 185, Issue:7

    Topics: Aged; Female; Humans; Myasthenia Gravis; Verapamil

1989
Acute effects of verapamil on neuromuscular transmission in patients with myasthenia gravis.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1987, Volume: 11, Issue:3

    Topics: Adult; Blood Pressure; Electrocardiography; Electromyography; Female; Heart Rate; Humans; Male; Midd

1987