Page last updated: 2024-10-24

verapamil and Muscular Dystrophy

verapamil has been researched along with Muscular Dystrophy in 8 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Research Excerpts

ExcerptRelevanceReference
" At a dosage of 20 mg/kg/day, drug therapy in each case significantly prolonged the functional ability of the dystrophic chickens as quantitated regularly by a standardized test for righting ability."1.27In vivo effects of three calcium blockers on chickens with inherited muscular dystrophy. ( Heffner, RR; Hudecki, MS; Pollina, CM, 1984)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's4 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Emery, AE2
Skinner, R1
Howden, LC1
Matthews, MB1
Zalman, F1
Perloff, JK1
Durant, NN1
Campion, DS1
Hudecki, MS1
Pollina, CM1
Heffner, RR1
Anand, R1
Benders, AA1
Wevers, RA1
Veerkamp, JH1
Bkaily, G1
Jasmin, G1
Tautu, C1
Prochek, L1
Yamamoto, T1
Sculptoreanu, A1
Peyrow, M1
Jacques, D1
García, AM1
Goldemberg, AL1
Fernández, H1
Fortunato, M1
Ricci, L1
Trucco, RE1
Ilan, Y1
Hillman, M1
Oren, R1

Trials

1 trial available for verapamil and Muscular Dystrophy

ArticleYear
Verapamil in Duchenne muscular dystrophy.
    Lancet (London, England), 1982, Mar-06, Volume: 1, Issue:8271

    Topics: Child; Clinical Trials as Topic; Double-Blind Method; Humans; Muscular Dystrophies; Risk; Verapamil

1982

Other Studies

7 other studies available for verapamil and Muscular Dystrophy

ArticleYear
Acute respiratory failure following intravenous verapamil in Duchenne's muscular dystrophy.
    American heart journal, 1983, Volume: 105, Issue:3

    Topics: Adolescent; Atrial Flutter; Humans; Ion Channels; Male; Muscular Dystrophies; Respiratory Insufficie

1983
In vivo effects of three calcium blockers on chickens with inherited muscular dystrophy.
    Experimental neurology, 1984, Volume: 84, Issue:3

    Topics: Animals; Benzazepines; Calcium; Chickens; Creatine Kinase; Diltiazem; Disease Models, Animal; Female

1984
Verapamil and calcium-stimulated enzyme efflux from skeletal muscle.
    Clinical chemistry, 1982, Volume: 28, Issue:7

    Topics: Calcium; Creatine Kinase; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Muscles; Muscular Dy

1982
Ion transport in human skeletal muscle cells: disturbances in myotonic dystrophy and Brody's disease.
    Acta physiologica Scandinavica, 1996, Volume: 156, Issue:3

    Topics: Acetylcholine; Adolescent; Adult; Biological Transport, Active; Calcium; Calcium Channel Blockers; C

1996
A tetrodotoxin- and Mn2(+)-insensitive Na+ current in Duchenne muscular dystrophy.
    Muscle & nerve, 1990, Volume: 13, Issue:10

    Topics: Adolescent; Calcium Channel Blockers; Calcium Channels; Child; Child, Preschool; Culture Techniques;

1990
Effect of chronic administration of verapamil in Duchenne muscular dystrophy.
    General pharmacology, 1990, Volume: 21, Issue:6

    Topics: 4-Nitrophenylphosphatase; Adolescent; Alkaline Phosphatase; Child; Child, Preschool; Creatine Kinase

1990
Intravenous verapamil for tachyarrhythmia in Duchenne's muscular dystrophy.
    Pediatric cardiology, 1990, Volume: 11, Issue:3

    Topics: Adolescent; Heart Failure; Heart Rate; Humans; Infusions, Intravenous; Male; Muscular Dystrophies; T

1990