Page last updated: 2024-10-24

verapamil and Muscle Relaxation

verapamil has been researched along with Muscle Relaxation in 117 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"Experiments were carried out in vitro on a new antispasmodic drug, 2-(diethylamino)-1-methylethyl-cis-1-hydroxy[bicyclohexyl] -2-carboxylate (rociverine), to elucidate further the mechanism of its smooth-muscle relaxation."7.67Mechanism of smooth muscle relaxation by rociverine. ( Brunori, P; D'Agostino, G; Grana, E; Santagostino Barbone, MG; Subissi, A; Zonta, F, 1984)
"The effects of verapamil or diltiazem on pressor responses to posterior hypothalamic stimulation, injected noradrenaline or tyramine were studied in urethane-anaesthetized normotensive, deoxycorticosterone acetate (DOCA), renal and spontaneously hypertensive rats at the early and established phases of hypertension."3.68Failure of verapamil and diltiazem to attenuate the pressor response to hypothalamic stimulation: a possible mechanism. ( Eferakeya, AE; Osunkwo, UA, 1992)
"Experiments were carried out in vitro on a new antispasmodic drug, 2-(diethylamino)-1-methylethyl-cis-1-hydroxy[bicyclohexyl] -2-carboxylate (rociverine), to elucidate further the mechanism of its smooth-muscle relaxation."3.67Mechanism of smooth muscle relaxation by rociverine. ( Brunori, P; D'Agostino, G; Grana, E; Santagostino Barbone, MG; Subissi, A; Zonta, F, 1984)
" The here obtained pharmacodynamic profiles of the drugs suggest that both milrinone and theophylline may be considered as potent relaxing agents of the lower oesophageal sphincter."1.35Milrinone and theophylline act as lower oesophageal sphincter relaxing agents: a comparative pharmacodynamic study in the rabbit. ( Batzias, GC; Koutsoviti-Papadopoulou, M; Psarra, TA, 2009)
"Pretreatment with verapamil (10(-6) mol/L) or nickel (Ni(2+)) (2 mmol/L) inhibited the contractions to a magnitude of 63."1.32Application of electric field stimulation for investigations of human placental blood vessels. ( Falkay, G; Gáspár, R; Resch, BE, 2003)
"Diltiazem was the less effective drug on both left ventricular hemodynamics and coronary circulation."1.30Calcium-channel blockers preserve coronary endothelial reactivity after ischemia-reperfusion. ( Buluran, J; Cartier, R; Dagenais, F; Hollmann, C, 1997)
"Dipyridamole or NBTI treatment, like diazepam, increased the responsiveness of rat pulmonary artery to CGS 21680, but did not influence the cardiodepressive effect of CPA in electrically driven left atrial myocardium."1.30Sensitization by chronic diazepam treatment of A2A adenosine receptor-mediated relaxation in rat pulmonary artery. ( Cseppentö, A; Kovács, P; Nagy, E; Szabó, JZ; Szentmiklósi, AJ; Ujfalusi, A, 1999)
"Pretreatment with verapamil (1 or 10 microM), nifedipine (0."1.29The effects of phorbol 12,13-diacetate on responses of guinea-pig isolated trachea to methylxanthines, isoprenaline and ryanodine. ( Cortijo, J; Morcillo, EJ; Sanz, CM; Small, RC; Villagrasa, V, 1994)
" In the isolated guinea-pig ileum or taeniae coli, Ost and Ver were both found to inhibit the contractions induced by acetylcholine (ACh), histamine (His) and KCl in a dose-dependent manner; and noncompetitively antagonize the CaCl2 cumulative dose-response curves, with pD2 values of 4."1.29[Effects of osthole on the isolated guinea-pig ileum and taeniae coli]. ( Li, L; Zhao, DK; Zhao, GS; Zhuang, FE, 1993)
"Fraxinellone and verapamil were more potent and effective in producing relaxation in 60 mmol/l than in 15 mmol/l K(+)-induced contraction."1.28Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers. ( Huang, TF; Ko, FN; Su, MJ; Teng, CM; Wang, ML; Wu, TS; Yu, SM, 1992)
"Verapamil was found to produce considerable tracheal smooth muscle relaxation from a threshold concentration of 2 X 10(-7) M and with maximum effect at 10(-3) M."1.27The potential bronchodilator action of verapamil. ( Cade, JF; Clegg, EA; Moulds, RF; Pain, MC; Rubinfeld, AR; Santamaria, JD, 1984)
"The relaxant effects of five organic calcium antagonists (nicardipine, diltiazem, PY 108068, verapamil and bepridil) on guinea-pig isolated trachea were tested against contractions induced by acetylcholine, histamine, 5-hydroxytryptamine, potassium chloride (KCl) and tetraethylammonium (TEA) in a medium containing the normal amount of calcium and against calcium dose-response curves in a calcium-free, potassium-enriched medium."1.27Effects of five different organic calcium antagonists on guinea-pig isolated trachea. ( Advenier, C; Cerrina, J; Duroux, P; Floch, A; Renier, A, 1984)
"Indapamide was given orally to SHR and WKY rats for 2 weeks at a dose of 5 mg/kg per day."1.27Further study of possible direct vascular actions of indapamide in the conduit and renal arteriolar vessels of spontaneously hypertensive rats. ( De Groot, G; De Wildt, DJ; Hillen, FC; Van de Kuil, A, 1988)
"When verapamil was used to relax EFS and matched methacholine contractions, cervical trachealis was completely relaxed whereas thoracic trachealis relaxed to 15% of induced tone."1.27Regional differences in relaxation of electric field-stimulated canine airway smooth muscle by verapamil, isoproterenol and prostaglandin E2. ( Abel, PW; Moore, DH; Puckett, AM; Rinard, GA; Walter, JB, 1986)
"05) shifts to the right of the histamine dose-response curve in normal physiological salt solution (PSS)."1.27Differential effects of adenosine and verapamil on histamine vascular contractions. ( Merrill, GF; Tozzi, CA, 1986)
"When amrinone was examined for its inhibition of histamine contractions under modified Ca2+ availability, the EC25 and EC75 of amrinone were 76 and 8 times smaller, respectively, under conditions of intracellular rather than normal Ca2+ availability."1.26Relaxant effects of amrinone upon pulmonary smooth muscle. ( Buck, DC; Mielens, ZE, 1982)

Research

Studies (117)

TimeframeStudies, this research(%)All Research%
pre-199050 (42.74)18.7374
1990's51 (43.59)18.2507
2000's10 (8.55)29.6817
2010's6 (5.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Janis, RA2
Triggle, DJ1
Pirotte, B1
de Tullio, P1
Florence, X1
Goffin, E1
Somers, F1
Boverie, S1
Lebrun, P1
Wei, YY1
Sun, LL1
Fu, ST1
Hsu, HT1
Yang, YL1
Chen, WC1
Chen, CM1
Ko, WC1
Reinke, Y1
Gross, S1
Eckerle, LG1
Hertrich, I1
Busch, M1
Busch, R1
Riad, A1
Rauch, BH1
Stasch, JP1
Dörr, M1
Felix, SB1
Valero, MS1
Oliván-Viguera, A1
Garrido, I1
Langa, E1
Berzosa, C1
López, V1
Gómez-Rincón, C1
Murillo, MD1
Köhler, R1
Koutsoviti-Papadopoulou, M1
Psarra, TA1
Batzias, GC1
Krönström, J1
Karlsson, W1
Johansson, BR1
Holmgren, S1
Bastos, VP1
Brito, TS1
Lima, FJ1
Pinho, JP1
Lahlou, S1
Abreu Matos, FJ1
Santos, AA1
Caldas Magalhães, PJ1
Brankovic, SV1
Kitic, DV1
Radenkovic, MM1
Veljkovic, SM1
Golubovic, TD1
Kito, Y1
Suzuki, H1
Resch, BE1
Gáspár, R1
Falkay, G1
Ergün, Y1
Pangalis, A2
Giala, M1
Mironidou, M1
Papadakis, E1
Crassaris, L1
Paradelis, AG1
Ma, LL1
Liu, YQ1
Tang, WH1
Zhao, LM1
Jiang, H1
Lau, LC1
Adaikan, PG1
Daenas, C1
Hatziefthimiou, AA1
Gourgoulianis, KI1
Molyvdas, PA1
Townley, RG1
Yasuda, N1
Sakai, Y1
Wikberg, JE1
Flaim, SF1
Irwin, JM1
Ratz, PH1
Swigart, SC1
Radulović, S1
Kazić, T1
Kawanishi, M1
Baba, K1
Tomita, T2
Cade, JF1
Clegg, EA1
Moulds, RF1
Santamaria, JD1
Rubinfeld, AR1
Pain, MC1
Toda, N1
D'Agostino, G1
Zonta, F1
Santagostino Barbone, MG1
Grana, E1
Brunori, P1
Subissi, A1
Robinson, CP1
Advenier, C2
Cerrina, J1
Duroux, P1
Floch, A1
Renier, A1
Hof, RP1
Vuorela, HJ1
Maggi, CA1
Grimaldi, G1
Meli, A1
Ohhashi, T1
Azuma, T1
Webb, RC1
Mielens, ZE1
Buck, DC1
Ozaki, H3
Shibata, S2
Kitano, H1
Matsumoto, P1
Ishida, Y1
Kishimoto, T1
Urakawa, N3
Levy, JV1
Park, SJ1
Boulanger, CM1
Kirchengast, M1
Vanhoutte, PM2
Randall, MD1
McCulloch, AI1
Morales, MA1
Silva, A1
Brito, G1
Bustamante, S1
Ponce, H1
Paeile, C1
Yokoyama, T1
Kasai, H1
Okada, Y1
Izumi, H1
Izawa, T1
Ogawa, N1
Nielsen, CB2
Yu, SM2
Lee, SS1
Hou, YS1
Teng, CM2
Cortijo, J2
Sanz, CM1
Villagrasa, V1
Morcillo, EJ2
Small, RC1
Li, L1
Zhuang, FE1
Zhao, GS1
Zhao, DK1
Romanelli, MN1
Dei, S1
Scapecchi, S1
Teodori, E1
Gualtieri, F1
Budriesi, R1
Mannhold, R1
Ivorra, MD1
Chuliá, S1
Noguera, MA1
D'Ocon, MP1
Chatelain, P1
Clinet, M1
Polster, P1
Christophe, B1
Manning, AS1
Karaki, H3
Sudjarwo, SA1
Hori, M1
Takai, M1
Urade, Y1
Okada, T1
Villanove, X1
Marthan, R1
Tunon de Lara, JM1
Johnson, PR1
Savineau, JP1
McKay, KO1
Alouan, LA1
Armour, CL1
Black, JL1
Kerfoot, WW1
Park, HY1
Schwartz, LB1
Hagen, PO1
Carson, CC1
Ito, Y2
Takagi, K1
Lin, WC1
Chang, HL1
Brown, RA1
Sundareson, AM1
Lee, MM1
Savage, AO1
Asano, M1
Kuwako, M1
Nomura, Y1
Ito, KM1
Ito, K1
Uyama, Y1
Imaizumi, Y1
Watanabe, M1
Hadjkaddour, K1
Michel, A1
Laurent, F1
Boucard, M1
Salomone, S1
Silva, CL1
Morel, N1
Godfraind, T1
Peiper, U1
Knipp, SC1
Thies, B1
Henke, R1
Katoch, SS1
Rüegg, JC1
Pfitzer, G1
Dagenais, F1
Cartier, R1
Hollmann, C1
Buluran, J1
Vassilev, PP1
Corompt, E1
Bessard, G1
Lantuejoul, S1
Naline, E1
Devillier, P1
Doggrell, SA1
Liang, LC1
Glusa, E1
Gräser, T1
Wagner, S1
Oettel, M1
Wong, KK2
Fröhlich, G1
Burmeister, S1
Wiedemann, A1
Bulitta, M1
Kwok, KH1
Chan, NW1
Lau, CW1
Huang, Y1
Yaktubay, N1
Ogülener, N1
Onder, S1
Baysal, F1
Ujfalusi, A1
Cseppentö, A1
Nagy, E1
Szabó, JZ1
Kovács, P1
Szentmiklósi, AJ1
Tolsa, JF1
Gao, Y1
Raj, JU1
Yamaki, K1
Sim, JH1
Kim, YC1
Kim, SJ1
Lee, SJ1
Suh, SH1
Jun, JY1
So, I1
Kim, KW1
Toyama, S1
Suzuki, K1
Diamond, J1
Mikkelsen, E2
Andersson, KE2
Pedersen, OL1
De Mey, JG1
Uchida, E1
Miasiro, N2
Paiva, AC2
Sanagi, M1
Mitsui, M1
Tzeng, SF1
Hirano, S1
Agata, N1
Hara, Y1
Iguchi, H1
Shirai, M1
Tone, H1
Eferakeya, AE1
Osunkwo, UA1
Ko, FN1
Su, MJ1
Wu, TS1
Wang, ML1
Huang, TF1
Foster, KA1
Arch, JR1
Newson, PN1
Shaw, D1
Taylor, SG1
Yu, DY1
Alder, VA1
Su, EN1
Cringle, SJ1
Nielsen-Kudsk, JE2
Mellemkjaer, S1
Weir, CJ1
Gibson, IF1
Martin, W1
Chiou, WF1
Yen, MH1
Chen, CF1
Satake, N1
Oe, H1
Nasu, Y1
Sakamoto, Y1
Bang, L1
Brønsgaard, AM1
Lin, WW1
Lee, CY1
Nikitina, EI1
Ferrari, R1
Cargnoni, A1
Rodella, A1
Ciampalini, G1
Raddino, R1
Katsoulis, S2
Conlon, JM2
Yanagisawa, T2
Kawada, M1
Taira, N2
Ubeda, A1
Villar, A1
Edvinsson, L1
Ikomi-Kumm, J1
Monti, M1
Koga, Y1
Sodeyama, N1
Satoh, S1
Teshigawara, T1
Endoh, M1
Nagase, H1
Akbarali, HI1
Bieger, D1
Triggle, CR1
Chen, SH1
Yin, ZZ1
Ma, BB1
Shi, ZX1
Miyazaki, Y1
Ogawa, K1
Satake, T1
Sugiyama, S1
Ozawa, T1
Sutter, MC1
May, PB1
Lim, SL1
Lai, FM1
Cobuzzi, A1
Tanikella, T1
Cervoni, P1
Esau, SA1
Zeng, XP1
Yang, W1
Wang, ZG1
De Wildt, DJ1
Van de Kuil, A1
Hillen, FC1
De Groot, G1
Paradelis, A1
Moore, DH1
Abel, PW1
Rinard, GA1
Puckett, AM1
Walter, JB1
Sawamura, M1
Kobayashi, Y1
Nara, Y1
Hattori, K1
Yamori, Y1
Lombard, JH1
Smeda, J1
Madden, JA1
Harder, DR1
Perpiñá, M1
Esplugues, J1
Andrejauskas, E1
Hertel, R1
Marmé, D1
Tozzi, CA1
Merrill, GF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Identifying the Pathophysiology of Neurogenic Orthostatic Hypotension and the Effects of Melatonin on Reducing Supine Hypertension in Peripherally Intact Versus Denervated Post-ganglionic Sympathetic Nerves[NCT02963181]Early Phase 110 participants (Actual)Interventional2018-03-01Terminated (stopped due to PI leaving)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for verapamil and Muscle Relaxation

ArticleYear
New developments in Ca2+ channel antagonists.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:6

    Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Electrophysiology; Heart; Hum

1983
[Mechanism of action of calcium-antagonists on the smooth vascular muscles].
    Cardiologia (Rome, Italy), 1985, Volume: 30, Issue:5

    Topics: Calcium; Calcium Channel Blockers; Diltiazem; Ion Channels; Muscle Contraction; Muscle Relaxation; M

1985

Trials

1 trial available for verapamil and Muscle Relaxation

ArticleYear
[Intravesical instillation of trospium chloride, oxybutynin and verapamil for relaxation of the bladder detrusor muscle. A placebo controlled, randomized clinical test].
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:5

    Topics: Adult; Benzilates; Calcium Channel Blockers; Female; Humans; Injections; Male; Mandelic Acids; Muscl

1998

Other Studies

114 other studies available for verapamil and Muscle Relaxation

ArticleYear
1,4,2-Benzo/pyridodithiazine 1,1-dioxides structurally related to the ATP-sensitive potassium channel openers 1,2,4-Benzo/pyridothiadiazine 1,1-dioxides exert a myorelaxant activity linked to a distinct mechanism of action.
    Journal of medicinal chemistry, 2013, Apr-25, Volume: 56, Issue:8

    Topics: Animals; Benzothiadiazines; Diazoxide; Insulin-Secreting Cells; KATP Channels; Muscle Relaxation; Mu

2013
HEF-19-induced relaxation of colonic smooth muscles and the underlying mechanisms.
    World journal of gastroenterology, 2013, Aug-28, Volume: 19, Issue:32

    Topics: Acetylcholine; Animals; Barium Compounds; Calcium Channel Blockers; Calcium Channels; Calcium Chlori

2013
Butylidenephthalide blocks potassium channels and enhances basal tension in isolated guinea-pig trachea.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Calcium Channel Blockers; Drug Antagonism; Guinea Pigs; Male; Muscle Relaxation; Nifedipine

2014
The soluble guanylate cyclase stimulator riociguat and the soluble guanylate cyclase activator cinaciguat exert no direct effects on contractility and relaxation of cardiac myocytes from normal rats.
    European journal of pharmacology, 2015, Nov-15, Volume: 767

    Topics: Animals; Benzoates; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergis

2015
Rock Tea extract (Jasonia glutinosa) relaxes rat aortic smooth muscle by inhibition of L-type Ca(2+) channels.
    Journal of physiology and biochemistry, 2015, Volume: 71, Issue:4

    Topics: Animals; Antihypertensive Agents; Aorta; Asteraceae; Calcium Channel Blockers; Calcium Channels, L-T

2015
Milrinone and theophylline act as lower oesophageal sphincter relaxing agents: a comparative pharmacodynamic study in the rabbit.
    Journal of veterinary pharmacology and therapeutics, 2009, Volume: 32, Issue:2

    Topics: Animals; Bronchodilator Agents; Esophageal Sphincter, Lower; Female; Male; Milrinone; Muscle Relaxat

2009
Involvement of contractile elements in control of bioluminescence in Northern krill, Meganyctiphanes norvegica (M. Sars).
    Cell and tissue research, 2009, Volume: 336, Issue:2

    Topics: Actin Cytoskeleton; Animals; Euphausiacea; Immunohistochemistry; Light; Luminescence; Muscle Relaxat

2009
Inhibitory effect of 1,8-cineole on guinea-pig airway challenged with ovalbumin involves a preferential action on electromechanical coupling.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:11

    Topics: Animals; Bronchodilator Agents; Cyclohexanols; Dose-Response Relationship, Drug; Eucalyptol; Guinea

2009
Calcium blocking activity as a mechanism of the spasmolytic effect of the essential oil of Calamintha glandulosa Silic on the isolated rat ileum.
    General physiology and biophysics, 2009, Volume: 28 Spec No

    Topics: Animals; Calcium; Calcium Chloride; Cyclohexane Monoterpenes; Dose-Response Relationship, Drug; Ileu

2009
Properties of Rikkunshi-to (TJ-43)-induced relaxation of rat gastric fundus smooth muscles.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:5

    Topics: Animals; Apamin; Drugs, Chinese Herbal; Enprostil; Gastric Fundus; Hesperidin; Membrane Potentials;

2010
Application of electric field stimulation for investigations of human placental blood vessels.
    Obstetrics and gynecology, 2003, Volume: 101, Issue:2

    Topics: Adult; Animals; Culture Techniques; Electric Stimulation; Female; Gestational Age; Humans; Mesenteri

2003
Differential effects of nifedipine and verapamil on non-adrenergic non-cholinergic relaxations at different levels of active tone: assessment of the contribution of nerve-derived hyperpolarizing factor.
    Autonomic & autacoid pharmacology, 2005, Volume: 25, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Gastric

2005
Interaction of aminoglycoside antibiotics with H2-blockers and calcium channel blockers in isolated smooth muscles of rat aorta.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Calcium Channel Blockers; Cimetidine; His

1989
Experimental study of verapamil on the relaxation of isolated human corpus cavernosum tissues.
    Asian journal of andrology, 2006, Volume: 8, Issue:2

    Topics: Adult; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Penis; Verapa

2006
Mechanisms of direct relaxant effect of sildenafil, tadalafil and vardenafil on corpus cavernosum.
    European journal of pharmacology, 2006, Jul-17, Volume: 541, Issue:3

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium; Carbolines; Dose-Response Relationship, Drug;

2006
Azithromycin has a direct relaxant effect on precontracted airway smooth muscle.
    European journal of pharmacology, 2006, Dec-28, Volume: 553, Issue:1-3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Anti-Bacterial Agents; Atropine; Azithromycin; Bronchodilator

2006
Role of calcium channel blocking agents in the treatment of allergic asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1984, Volume: 21, Issue:6

    Topics: Animals; Asthma; Basophils; Bronchial Provocation Tests; Bronchial Spasm; Calcium; Calcium Channel B

1984
A possible explanation for effects of Sr2+ on contraction-relaxation cycle in canine stomach.
    Comparative biochemistry and physiology. A, Comparative physiology, 1984, Volume: 78, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Carbachol; Cell Membrane; Dogs; Muscle Contraction; Muscle

1984
Reversal of alpha 1-receptor mediated relaxation in intestinal smooth muscle.
    Acta physiologica Scandinavica, 1981, Volume: 111, Issue:4

    Topics: Animals; Clonidine; Electrolytes; Female; Guinea Pigs; Intestines; Male; Muscle Contraction; Muscle

1981
Differential effects of calcium channel blocking agents on oxygen consumption rate in vascular smooth muscle.
    The American journal of cardiology, 1982, Feb-18, Volume: 49, Issue:3

    Topics: Animals; Aorta, Abdominal; Calcium; Calcium Channel Blockers; Diltiazem; Ion Channels; Male; Muscle

1982
Calcium antagonistic action of pentobarbitone on the isolated terminal ileum of the guinea-pig.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 266, Issue:1

    Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Guinea Pigs; Ileum; In Vitro Techniques;

1983
Effects of Na removal and readmission on the mechanical response in the guinea-pig tracheal smooth muscle.
    The Japanese journal of physiology, 1984, Volume: 34, Issue:1

    Topics: Animals; Calcium; Cell Membrane Permeability; Guinea Pigs; Ion Channels; Muscle Contraction; Muscle

1984
The potential bronchodilator action of verapamil.
    The Australian journal of experimental biology and medical science, 1984, Volume: 62 ( Pt 2)

    Topics: Animals; Barium; Barium Compounds; Bronchi; Chlorides; Dinoprost; Dose-Response Relationship, Drug;

1984
Responses of human, monkey and dog coronary arteries in vitro to carbocyclic thromboxane A2 and vasodilators.
    British journal of pharmacology, 1984, Volume: 83, Issue:2

    Topics: Adult; Aged; Animals; Coronary Vessels; Dinoprost; Dogs; Epoprostenol; Female; Humans; In Vitro Tech

1984
Mechanism of smooth muscle relaxation by rociverine.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:5

    Topics: Animals; Atropine; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Calcium; Cyclohexanecarboxylic

1984
Relaxation of rabbit aorta by chlordimeform.
    Journal of applied toxicology : JAT, 1984, Volume: 4, Issue:1

    Topics: Amidines; Animals; Aorta, Thoracic; Calcium; Chlorphenamidine; Dinoprost; Drug Interactions; In Vitr

1984
Effects of five different organic calcium antagonists on guinea-pig isolated trachea.
    British journal of pharmacology, 1984, Volume: 82, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Bepridil; Calcium Channel Blockers; Diltiazem; Dose-Response Relati

1984
Assessing calcium antagonism on vascular smooth muscle: a comparison of three methods.
    Journal of pharmacological methods, 1983, Volume: 9, Issue:1

    Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Female; In Vitro Techniques; Male; Musc

1983
The effects of nifedipine and verapamil on high K+ induced contractions of the rat intestinal tract in vivo.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:2

    Topics: Animals; Atropine; Blood Pressure; Duodenum; Heart Rate; Intestines; Male; Muscle Contraction; Muscl

1983
Contraction of arterial smooth muscle induced by magnesium ions.
    The American journal of physiology, 1982, Volume: 242, Issue:1

    Topics: Animals; Barium; Calcium; Dogs; Femoral Artery; Kinetics; Magnesium; Manganese; Muscle Contraction;

1982
D-600 and the membrane stabilizing effect of calcium in vascular smooth muscle.
    Pharmacology, 1982, Volume: 25, Issue:5

    Topics: Animals; Caffeine; Calcium; Gallopamil; Male; Membranes; Methoxamine; Muscle Relaxation; Muscle, Smo

1982
Relaxant effects of amrinone upon pulmonary smooth muscle.
    Pharmacology, 1982, Volume: 25, Issue:5

    Topics: Airway Resistance; Aminophylline; Aminopyridines; Amrinone; Animals; Barium; Calcium; Carbachol; Dru

1982
A comparative study of the relaxing effect of nitroprusside and verapamil on human umbilical vessels.
    Blood vessels, 1981, Volume: 18, Issue:6

    Topics: Calcium; Ferricyanides; Humans; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Nitropru

1981
A quantitative relationship between cellular Na accumulation and relaxation produced by ouabain in the depolarized smooth muscle of guinea-pig taenia coli.
    Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 312, Issue:2

    Topics: Animals; Calcium; Dinitrophenols; Guinea Pigs; In Vitro Techniques; Intestines; Intracellular Fluid;

1980
Cinepazet relaxation of aortic strips from normal and spontaneously hypertensive rats.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 29, Issue:1

    Topics: Animals; Aorta, Thoracic; Female; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscl

1980
Effects of the combined 5-hydroxytryptamine2 receptor and Ca2+ channel antagonist LU49938 on the responsiveness of isolated porcine coronary arteries with and without endothelium.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:3

    Topics: Analysis of Variance; Animals; Calcium-Binding Proteins; Coronary Vessels; Dinoprost; Dose-Response

1994
The involvement of ATP-sensitive potassium channels in beta-adrenoceptor-mediated vasorelaxation in the rat isolated mesenteric arterial bed.
    British journal of pharmacology, 1995, Volume: 115, Issue:4

    Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; B

1995
Vasorelaxant effect of the analgesic clonixin on rat aorta.
    General pharmacology, 1995, Volume: 26, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Effect of Kil769, a novel K(+)-channel opener, on sensitivity to Ca2+ of contractile elements and inositol phosphate formation in porcine coronary artery.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Calcium Channe

1995
Contraction induced either by iso-osmolar or hyper-osmolar potassium-rich solutions influences relaxant responses to pinacidil and verapamil in rat isolated aorta.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:10

    Topics: Animals; Aorta, Thoracic; Female; Guanidines; In Vitro Techniques; Kinetics; Male; Muscle Contractio

1993
Mechanisms of vasorelaxation induced by N-allylsecoboldine in rat thoracic aorta.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 349, Issue:6

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Aorta, Thoracic; Aporphines; Benzopyrans; Calcium

1994
The effects of phorbol 12,13-diacetate on responses of guinea-pig isolated trachea to methylxanthines, isoprenaline and ryanodine.
    British journal of pharmacology, 1994, Volume: 111, Issue:3

    Topics: Animals; Caffeine; Calcium Chloride; Cold Temperature; Drug Interactions; Female; Guinea Pigs; Hista

1994
[Effects of osthole on the isolated guinea-pig ileum and taeniae coli].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:12

    Topics: Acetylcholine; Animals; Calcium; Colon; Coumarins; Female; Guinea Pigs; Histamine Antagonists; Ileum

1993
Semi-rigid analogues of the calcium antagonist verapamil: a molecular modelling study.
    Journal of computer-aided molecular design, 1994, Volume: 8, Issue:2

    Topics: Animals; Aorta; Computer Graphics; Drug Design; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques;

1994
Intervention of two voltage-dependent calcium-entry pathways in the contractile response to acetylcholine and KCl in rat uterus.
    Pharmacology, 1994, Volume: 49, Issue:1

    Topics: Acetylcholine; Animals; Calcium; Calcium Channels; Diltiazem; Dose-Response Relationship, Drug; Fema

1994
In vitro characterization of a novel Ca2+ entry blocker: SR 33805.
    European journal of pharmacology, 1993, Aug-15, Volume: 246, Issue:3

    Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Diltiazem; Heart Rate; In Vitro Techniques;

1993
Induction of endothelium-dependent relaxation in the rat aorta by IRL 1620, a novel and selective agonist at the endothelin ETB receptor.
    British journal of pharmacology, 1993, Volume: 109, Issue:2

    Topics: Animals; Aorta, Thoracic; Arginine; Calcium; Carbachol; Endothelins; Endothelium, Vascular; In Vitro

1993
Sensitization decreases relaxation in human isolated airways.
    The American review of respiratory disease, 1993, Volume: 148, Issue:1

    Topics: Asthma; Benzopyrans; Bronchi; Bucladesine; Carbachol; Colforsin; Cromakalim; Dose-Response Relations

1993
Characterization of calcium channel blocker induced smooth muscle relaxation using a model of isolated corpus cavernosum.
    The Journal of urology, 1993, Volume: 150, Issue:1

    Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; El

1993
Relaxant actions of isoprenaline on guinea-pig isolated tracheal smooth muscle.
    British journal of pharmacology, 1995, Volume: 116, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Female; Guin

1995
Relaxant effects of berberine on the rat fundus.
    Research communications in molecular pathology and pharmacology, 1995, Volume: 90, Issue:3

    Topics: Animals; Berberine; Carbachol; Dose-Response Relationship, Drug; Muscle Relaxation; Muscle, Smooth;

1995
Differential effects of chronic calcium channel blocker treatment on the inotropic response of diabetic rat myocardium to acute ethanol exposure.
    Life sciences, 1996, Volume: 59, Issue:10

    Topics: Animals; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Drug Antagonism; Ethanol; Male;

1996
Possible mechanism of the potent vasoconstrictor actions of ryanodine on femoral arteries from spontaneously hypertensive rats.
    British journal of pharmacology, 1996, Volume: 118, Issue:4

    Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Femoral Artery; Male; Muscle

1996
Smooth muscle relaxant activity of A1- and A2-selective adenosine receptor agonists in guinea pig trachea: involvement of potassium channels.
    Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:3

    Topics: Adenosine; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Glyburide; Guinea Pi

1996
Facilitation of the vasorelaxant action of calcium antagonists by basal nitric oxide in depolarized artery.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:4

    Topics: Animals; Aorta; Calcium; Cyclic GMP; In Vitro Techniques; Isradipine; Male; Muscle Relaxation; Muscl

1996
Activation of protein kinase C accelerates contraction kinetics of airway smooth muscle.
    Pflugers Archiv : European journal of physiology, 1996, Volume: 432, Issue:3 Suppl

    Topics: Animals; Electrophysiology; Enzyme Activation; In Vitro Techniques; Indoles; Kinetics; Lactams; Musc

1996
Differential effects of a K+ channel agonist and Ca2+ antagonists on myosin light chain phosphorylation in relaxation of endothelin-1-contracted tracheal smooth muscle.
    Pflugers Archiv : European journal of physiology, 1997, Volume: 433, Issue:4

    Topics: Animals; Benzopyrans; Dihydropyridines; Endothelin-1; Muscle Relaxation; Muscle, Smooth; Myosin Ligh

1997
Calcium-channel blockers preserve coronary endothelial reactivity after ischemia-reperfusion.
    The Annals of thoracic surgery, 1997, Volume: 63, Issue:4

    Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Diltiazem; Dose-Response

1997
Effect of Ca2+-channel blockers on isoprenaline-induced desensitization in rat trachea.
    Life sciences, 1997, Volume: 61, Issue:21

    Topics: Animals; Calcium Channel Blockers; Carbachol; In Vitro Techniques; Isoproterenol; Male; Muscle Contr

1997
Inhibitory effects of large Ca2+-activated K+ channel blockers on beta-adrenergic- and NO-donor-mediated relaxations of human and guinea-pig airway smooth muscles.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1

    Topics: Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Albuterol; Animals; Benzimidazoles; Bronch

1998
The relaxing effect of BDF 9148 on the KCl-contracted aorta isolated from normo- and hyper-tensive rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:2

    Topics: Aging; Animals; Aorta, Thoracic; Azetidines; Calcium Channel Blockers; Cardiotonic Agents; Electroph

1998
Mechanisms of relaxation of rat aorta in response to progesterone and synthetic progestins.
    Maturitas, 1997, Dec-15, Volume: 28, Issue:2

    Topics: Animals; Aorta, Thoracic; Chlormadinone Acetate; Endothelium, Vascular; Estradiol; Estrogen Antagoni

1997
Drug induced contraction and relaxation in mouse isolated aorta.
    Artery, 1997, Volume: 22, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta

1997
Contractile and relaxant effects of tetrapentylammonium ions in rat isolated mesenteric artery.
    Pharmacology, 1998, Volume: 57, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium Channel Blocker

1998
Possible stimulation of Na+-K+-ATPase by NO produced from sodium nitrite by ultraviolet light in mouse gastric fundal strip.
    General pharmacology, 1999, Volume: 32, Issue:1

    Topics: Amiloride; Animals; Calcium; Female; Gastric Fundus; In Vitro Techniques; Male; Mice; Muscle Relaxat

1999
Sensitization by chronic diazepam treatment of A2A adenosine receptor-mediated relaxation in rat pulmonary artery.
    Life sciences, 1999, Volume: 64, Issue:2

    Topics: Adenosine; Animals; Carrier Proteins; Diazepam; Dinucleoside Phosphates; Dipyridamole; Dose-Response

1999
Developmental change in magnesium sulfate-induced relaxation of rabbit pulmonary arteries.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 87, Issue:5

    Topics: Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Calcium Channels; Female; In Vitro Tec

1999
Relaxant action produced by sodium nitroprusside in guinea-pig tracheal muscle.
    Respiration physiology, 1999, Sep-15, Volume: 117, Issue:2-3

    Topics: Animals; Atropine; Calcium; Cyclic GMP; Dinoprostone; Female; Fura-2; Guinea Pigs; Indoles; Indometh

1999
Capsaicin inhibits the voltage-operated calcium channels intracellularly in the antral circular myocytes of guinea-pig stomach.
    Life sciences, 2001, Apr-13, Volume: 68, Issue:21

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Capsaicin; Dose-Response Relationship, Drug; Fe

2001
[Calcium blocker (calcium antagonists) and angina pectoris].
    Nihon rinsho. Japanese journal of clinical medicine, 1977, Jan-10, Volume: 35, Issue:1

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Vessels; Calcium; Diltiazem; Female; Humans; Mus

1977
Relationship between cyclic nucleotide levels and drug-induced relaxation of smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 211, Issue:3

    Topics: Animals; Cyclic AMP; Cyclic GMP; Diazoxide; Drug Interactions; Female; Guinea Pigs; Hydralazine; In

1979
The effect of nifedipine on isolated human peripheral vessels.
    Acta pharmacologica et toxicologica, 1978, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Aged; Arteries; Calcium; Evoked Potentials; Female; Humans; Male; Middle Aged; Mu

1978
Contractile effects of prostaglandin F2alpha on isolated human peripheral arteries and veins.
    Acta pharmacologica et toxicologica, 1978, Volume: 43, Issue:5

    Topics: Adult; Aged; Arteries; Calcium; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

1978
Calcium-dependency of the direct relaxant effect of acetylcholine on canine femoral artery.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 236, Issue:2

    Topics: Acetylcholine; Animals; Calcium; Dogs; Femoral Artery; In Vitro Techniques; Muscle Contraction; Musc

1978
[Contraction and relaxation of vascular smooth muscle. Comparison of the origins of calcium employed in high potassium contraction and norepinephrine contraction].
    Nihon Heikatsukin Gakkai zasshi, 1976, Volume: 12, Issue:4

    Topics: Animals; Calcium; Dogs; In Vitro Techniques; Mesenteric Arteries; Muscle Contraction; Muscle Relaxat

1976
Effects of endothelin-1 and endothelin-3 on the isolated guinea pig ileum: role of Na+ ions and endothelin receptor subtypes.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 12

    Topics: Animals; Calcium; Dose-Response Relationship, Drug; Down-Regulation; Endothelins; Female; Guinea Pig

1992
Mechanism of relaxing action of the antiasthmatic drug, azelastine, in isolated porcine tracheal smooth muscle.
    European journal of pharmacology, 1992, Nov-10, Volume: 222, Issue:2-3

    Topics: Animals; Bronchodilator Agents; Carbachol; Cyclic AMP; Cyclic GMP; Endothelins; Muscle Contraction;

1992
Norepinephrine-induced contractile responses in isolated rat aortae from different duration of diabetes.
    Artery, 1992, Volume: 19, Issue:1

    Topics: Animals; Aorta, Thoracic; Bethanechol; Bethanechol Compounds; Diabetes Mellitus, Experimental; Dose-

1992
A possible mechanism of endothelium-dependent relaxation induced by pirarubicin and carbachol in rat isolated aorta.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:3

    Topics: Amiloride; Animals; Aorta, Thoracic; Calcium; Carbachol; Choline; Doxorubicin; Endothelium, Vascular

1992
Failure of verapamil and diltiazem to attenuate the pressor response to hypothalamic stimulation: a possible mechanism.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:5

    Topics: Animals; Aorta, Thoracic; Blood Pressure; Desoxycorticosterone; Diltiazem; Electric Stimulation; Fem

1992
Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Effect of Rb+ on cromakalim-induced relaxation and ion fluxes in guinea pig trachea.
    European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1

    Topics: Albuterol; Animals; Benzopyrans; Bronchodilator Agents; Cromakalim; Guinea Pigs; In Vitro Techniques

1992
Relaxation effects of diltiazem, verapamil, and tolazoline on isolated cat ophthalmociliary artery.
    Experimental eye research, 1992, Volume: 55, Issue:5

    Topics: Animals; Cats; Diltiazem; Dose-Response Relationship, Drug; Muscle Contraction; Muscle Relaxation; M

1992
Influence of osmolarity of solutions used for K+ contraction on relaxant responses to pinacidil, verapamil, theophylline and terbutaline in isolated airway smooth muscle.
    Pharmacology & toxicology, 1992, Volume: 70, Issue:1

    Topics: Animals; Guanidines; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle

1992
Effects of metabolic inhibitors on endothelium-dependent and endothelium-independent vasodilatation of rat and rabbit aorta.
    British journal of pharmacology, 1991, Volume: 102, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Antimetabolites; Aorta, Thoracic; Bu

1991
Mechanism of vasodilatory effect of berberine in rat mesenteric artery.
    European journal of pharmacology, 1991, Oct-29, Volume: 204, Issue:1

    Topics: Animals; Arginine; Berberine; Caffeine; Calcium Channels; Drug Interactions; Endothelium, Vascular;

1991
Vasorelaxing action of melatonin in rat isolated aorta; possible endothelium dependent relaxation.
    General pharmacology, 1991, Volume: 22, Issue:6

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta; Endothelium, Vascular; In Vitro Techniques; Mal

1991
Effects of endothelin-1 on the isolated guinea-pig ileum: role of Na+ ions.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:6

    Topics: Angiotensin II; Animals; Cyclic GMP; Drug Administration Schedule; Endothelins; Female; Guinea Pigs;

1990
Mechanisms of the depolarization and contracture due to Na removal in the circular muscle of the guinea-pig stomach.
    Nihon Heikatsukin Gakkai zasshi, 1990, Volume: 26, Issue:4

    Topics: Animals; Calcium; Cytoplasm; Female; Guinea Pigs; Male; Manganese; Muscle Contraction; Muscle Relaxa

1990
Glibenclamide blocks the relaxant action of pinacidil and cromakalim in airway smooth muscle.
    European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3

    Topics: Animals; Benzopyrans; Cromakalim; Female; Glyburide; Guanidines; Guinea Pigs; Histamine; In Vitro Te

1990
Biphasic effects of endothelin in the guinea-pig ileum.
    European journal of pharmacology, 1990, Jan-25, Volume: 176, Issue:1

    Topics: Animals; Calcium; Calcium Channels; Endothelins; Female; Guinea Pigs; Ileum; In Vitro Techniques; Ma

1990
[The relaxation of the coronary artery smooth muscles under the action of a high-potassium solution].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1990, Volume: 76, Issue:1

    Topics: Animals; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; In Vitro Techniques; Isotonic S

1990
Calcitonin gene-related peptides relax guinea pig and rat gastric smooth muscle.
    European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Nitroglycerin relaxes canine coronary arterial smooth muscle without reducing intracellular Ca2+ concentrations measured with fura-2.
    British journal of pharmacology, 1989, Volume: 98, Issue:2

    Topics: Animals; Benzofurans; Calcium; Coronary Vessels; Dogs; Female; Fura-2; In Vitro Techniques; Male; Mu

1989
Relaxant actions of khellin on vascular smooth muscle.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:4

    Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Female; In Vitro Techniques; Khellin; Male; Muscle Cont

1989
Effects of calcium entry blockers on human platelet metabolism measured by microcalorimetry.
    Human toxicology, 1989, Volume: 8, Issue:2

    Topics: Blood Platelets; Calcium Channel Blockers; Calorimetry; Cerebral Arteries; Diltiazem; Flunarizine; H

1989
Relaxation of airway smooth muscle induced by potassium in the presence of Ca-antagonists.
    Japanese journal of pharmacology, 1989, Volume: 50, Issue:4

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Mu

1989
Neurotensin and prostaglandin interactions in smooth muscle of the guinea pig stomach.
    European journal of pharmacology, 1988, Dec-13, Volume: 158, Issue:3

    Topics: Animals; Apamin; Aspirin; Drug Interactions; Guinea Pigs; Muscle Contraction; Muscle Relaxation; Mus

1988
The inhibitory effects of calmodulin antagonists on the endothelium-dependent relaxation in rabbit aorta.
    Nihon Heikatsukin Gakkai zasshi, 1986, Volume: 22, Issue:2

    Topics: Animals; Aorta; Calcimycin; Calmodulin; Carbachol; Endothelium; In Vitro Techniques; Male; Muscle Co

1986
Tetrodotoxin-sensitive and -insensitive relaxations in the rat oesophageal tunica muscularis mucosae.
    The Journal of physiology, 1986, Volume: 381

    Topics: Animals; Calcimycin; Esophagus; In Vitro Techniques; Muscarine; Muscle Contraction; Muscle Relaxatio

1986
[Calcium antagonism of allitridi].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:6

    Topics: Allyl Compounds; Animals; Aorta; Calcimycin; Calcium Channel Blockers; Female; Humans; In Vitro Tech

1988
Vasodilative effect of nicorandil on coronary artery.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:2

    Topics: Animals; Coronary Vessels; Dinoprost; Dogs; Female; Male; Muscle Relaxation; Niacinamide; Nicorandil

1985
Manganese can inhibit or potentiate contractile responses in mesenteric portal vein.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:6

    Topics: Animals; Barium; Calcium; Felodipine; Gallopamil; In Vitro Techniques; Male; Manganese; Mesenteric V

1988
Relaxant actions of viprostol and prostaglandin E2 on tracheal muscle and their effects on calcium influx.
    Prostaglandins, 1988, Volume: 36, Issue:1

    Topics: Animals; Calcium; Calcium Chloride; Carbachol; Dinoprostone; Guinea Pigs; Isoproterenol; Macaca fasc

1988
Slowing of relaxation in the fatiguing hamster diaphragm is enhanced by theophylline.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:3

    Topics: Animals; Caffeine; Calcium; Cricetinae; Diaphragm; In Vitro Techniques; Mesocricetus; Muscle Contrac

1988
[Relaxation effect of bovine parathyroid hormone 1-34 on rabbit aorta].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:4

    Topics: Animals; Aorta; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Sm

1988
Further study of possible direct vascular actions of indapamide in the conduit and renal arteriolar vessels of spontaneously hypertensive rats.
    European journal of pharmacology, 1988, Mar-15, Volume: 147, Issue:3

    Topics: Animals; Arterioles; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; In Vitro Technique

1988
Interaction of aminoglycoside antibiotics with calcium channel blockers at the smooth muscles of the isolated tracheal rings of the rat.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Calcium Chloride; Drug Interactions; In Vitro Techn

1987
Regional differences in relaxation of electric field-stimulated canine airway smooth muscle by verapamil, isoproterenol and prostaglandin E2.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Animals; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Isoprot

1986
Effect of extracellular calcium on vascular contraction induced by phorbol ester.
    Biochemical and biophysical research communications, 1987, May-29, Volume: 145, Issue:1

    Topics: Animals; Aorta, Thoracic; Calcium; In Vitro Techniques; Isometric Contraction; Male; Muscle Contract

1987
Effect of reduced oxygen availability upon myogenic depolarization and contraction of cat middle cerebral artery.
    Circulation research, 1986, Volume: 58, Issue:4

    Topics: Animals; Cats; Cerebral Arteries; Electrophysiology; Membrane Potentials; Muscle Contraction; Muscle

1986
Pharmacological characterization of the effects of verapamil and nifedipine on isolated guinea-pig lung parenchymal strip.
    General pharmacology, 1986, Volume: 17, Issue:2

    Topics: Acetylcholine; Animals; Calcium; Calcium Chloride; Guinea Pigs; Histamine; In Vitro Techniques; Isop

1986
3,4,5-Triiodobenzoic acid affects [3H]verapamil binding to plant and animal membrane fractions and smooth muscle contraction.
    Biochemical and biophysical research communications, 1986, Aug-14, Volume: 138, Issue:3

    Topics: Animals; Calcium; Calcium Channel Blockers; Cell Membrane; In Vitro Techniques; Indoleacetic Acids;

1986
Differential effects of adenosine and verapamil on histamine vascular contractions.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:6

    Topics: Adenosine; Animals; Calcium; Chlorpheniramine; Histamine; In Vitro Techniques; Male; Muscle Relaxati

1986