Page last updated: 2024-10-24

verapamil and Morphine Dependence

verapamil has been researched along with Morphine Dependence in 8 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.

Research Excerpts

ExcerptRelevanceReference
"Verapamil was used to isolate NMDA-dependent LTP."1.32Dependence on morphine leads to a prominent sharing among the different mechanisms of long-term potentiation in the CA1 region of rat hippocampus. ( Fathollahi, Y; Kazemnejad, A; Salmanzadeh, F; Semnanian, S; Shafizadeh, M, 2003)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Duan, Y1
Jin, L1
Du, W1
Meng, Y1
Liang, J1
Zhang, J1
Sui, N1
Shen, F1
Salmanzadeh, F1
Fathollahi, Y1
Semnanian, S1
Shafizadeh, M1
Kazemnejad, A1
Leventhal, L1
Cosmi, S1
Deecher, D1
Blackburn-Munro, G1
Brown, CH1
Neumann, ID1
Landgraf, R1
Russell, JA1
Schnur, P1
Espinoza, M1
Flores, R1
Ortiz, S1
Vallejos, S1
Wainwright, M1
Barrios, M1
Baeyens, JM2
Bongianni, F1
Carla, V1
Moroni, F1
Pellegrini-Giampietro, DE1
Esposito, E1
Ossowska, G1
Samanin, R1

Other Studies

8 other studies available for verapamil and Morphine Dependence

ArticleYear
Distinctive roles of L-type calcium channels subtypes within the dorsal hippocampus in formation of morphine withdrawal-induced aversion in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2023, 12-20, Volume: 127

    Topics: Animals; Avoidance Learning; Calcium Channels, L-Type; Hippocampus; Morphine; Morphine Dependence; N

2023
Dependence on morphine leads to a prominent sharing among the different mechanisms of long-term potentiation in the CA1 region of rat hippocampus.
    Brain research, 2003, Feb-14, Volume: 963, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Calcium Channel Blockers; Cognition; Electri

2003
Effect of calcium channel modulators on temperature regulation in ovariectomized rats.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 80, Issue:3

    Topics: Amines; Animals; Body Temperature Regulation; Calcium Channel Blockers; Calcium Channels; Cyclohexan

2005
Verapamil prevents withdrawal excitation of oxytocin neurones in morphine-dependent rats.
    Neuropharmacology, 2000, Jul-10, Volume: 39, Issue:9

    Topics: Animals; Animals, Suckling; Calcium Channel Blockers; Calcium Channels, L-Type; Electric Stimulation

2000
Blocking naloxone-precipitated withdrawal in rats and hamsters.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:4

    Topics: Animals; Behavior, Animal; Clonidine; Cricetinae; Drug Implants; Mesocricetus; Morphine Dependence;

1992
Differential effects of L-type calcium channel blockers and stimulants on naloxone-precipitated withdrawal in mice acutely dependent on morphine.
    Psychopharmacology, 1991, Volume: 104, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Calcium channel inhibitors suppress the morphine-withdrawal syndrome in rats.
    British journal of pharmacology, 1986, Volume: 88, Issue:3

    Topics: Animals; Behavior, Animal; Brain Chemistry; Calcium Channel Blockers; Methoxyhydroxyphenylglycol; Mo

1986
Effects of peripheral and central administration of calcium channel blockers in the naloxone-precipitated abstinence syndrome in morphine-dependent rats.
    European journal of pharmacology, 1987, May-07, Volume: 137, Issue:1

    Topics: Animals; Body Weight; Brain; Calcium Channel Blockers; Clonidine; Diarrhea; Flunarizine; Injections,

1987