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verapamil and Mast-Cell Sarcoma

verapamil has been researched along with Mast-Cell Sarcoma in 3 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Mast-Cell Sarcoma: A unifocal malignant tumor that consists of atypical pathological MAST CELLS without systemic involvement. It causes local destructive growth in organs other than in skin or bone marrow.

Research Excerpts

ExcerptRelevanceReference
"Verapamil was shown to increase growth inhibition and decrease viability of PY815 mastocytoma cells treated with the anti-cancer drug mAMSA 4'-(9-acridinylamino)methanesulphon-m-anisidide (mAMSA) or its normally inactive congener, 4'-(9-acridinylamino)methanesulphon-o-anisidide (oAMSA)."1.27Potentiation of 4'-(9-acridinylamino)methanesulphon-m-anisidine) action by verapamil. ( Darkin, S; Ralph, RK, 1986)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gately, MK1
Martz, E1
Darkin, S1
Ralph, RK1
Utsunomiya, N1
Tsuboi, M1
Nakanishi, M1

Other Studies

3 other studies available for verapamil and Mast-Cell Sarcoma

ArticleYear
Early steps in specific tumor cell lysis by sensitized mouse T lymphocytes. V. Evidence that manganese inhibits a calcium-dependent step in programming for lysis.
    Cellular immunology, 1981, Volume: 61, Issue:1

    Topics: Animals; Calcium; Cobalt; Cytotoxicity, Immunologic; Lanthanum; Manganese; Mast-Cell Sarcoma; Mice;

1981
Potentiation of 4'-(9-acridinylamino)methanesulphon-m-anisidine) action by verapamil.
    Cancer letters, 1986, Volume: 30, Issue:1

    Topics: Aminoacridines; Amsacrine; Animals; Cell Line; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug

1986
Early transmembrane events in alloimmune cytotoxic T-lymphocyte activation as revealed by stopped-flow fluorometry.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:6

    Topics: Animals; Biological Transport; Calcium; Cell Line; Concanavalin A; Cytotoxicity Tests, Immunologic;

1986