verapamil has been researched along with Malaria, Falciparum in 10 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ellagic acid is a polyphenol found in various plant products." | 1.35 | In vitro and in vivo properties of ellagic acid in malaria treatment. ( Benoit-Vical, F; Berry, A; Garcia-Alvarez, MC; Nicolau, ML; Olagnier, D; Soh, PN; Witkowski, B, 2009) |
| "Control of falciparum malaria has become almost impossible in many areas due to the development of resistance to chloroquine and other antimalarial drugs." | 1.29 | Relationship of global chloroquine transport and reversal of resistance in Plasmodium falciparum. ( Boulter, MK; Bray, PG; Howells, RE; Ritchie, GY; Ward, SA, 1994) |
| "Cyproheptadine and verapamil were not effective in reversing chloroquine resistance and probable drug toxicity was observed with these drugs in combination with chloroquine." | 1.29 | Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys. ( Kyle, DE; Milhous, WK; Rossan, RN, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soh, PN | 1 |
| Witkowski, B | 2 |
| Olagnier, D | 1 |
| Nicolau, ML | 1 |
| Garcia-Alvarez, MC | 1 |
| Berry, A | 1 |
| Benoit-Vical, F | 1 |
| Ross, LS | 1 |
| Dhingra, SK | 1 |
| Mok, S | 1 |
| Yeo, T | 1 |
| Wicht, KJ | 1 |
| Kümpornsin, K | 1 |
| Takala-Harrison, S | 1 |
| Fairhurst, RM | 1 |
| Ariey, F | 1 |
| Menard, D | 1 |
| Fidock, DA | 1 |
| Ciach, M | 1 |
| Zong, K | 1 |
| Kain, KC | 1 |
| Crandall, I | 1 |
| Chen, N | 1 |
| Kyle, DE | 2 |
| Pasay, C | 1 |
| Fowler, EV | 1 |
| Baker, J | 1 |
| Peters, JM | 1 |
| Cheng, Q | 1 |
| Tamez, PA | 1 |
| Lantvit, D | 1 |
| Lim, E | 1 |
| Pezzuto, JM | 1 |
| Bray, PG | 2 |
| Boulter, MK | 1 |
| Ritchie, GY | 1 |
| Howells, RE | 1 |
| Ward, SA | 2 |
| Milhous, WK | 1 |
| Rossan, RN | 1 |
| Adovelande, J | 1 |
| Delèze, J | 1 |
| Schrével, J | 1 |
| Mungthin, M | 1 |
| Rafatro, H | 1 |
| Ramanitrahasimbola, D | 1 |
| Rasoanaivo, P | 1 |
| Ratsimamanga-Urverg, S | 1 |
| Rakoto-Ratsimamanga, A | 1 |
| Frappier, F | 1 |
10 other studies available for verapamil and Malaria, Falciparum
| Article | Year |
|---|---|
In vitro and in vivo properties of ellagic acid in malaria treatment.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Chloroquine; Dose-Response Relationshi | 2009 |
Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine.
Topics: Animals; Antimalarials; Cambodia; Cell Shape; Chloroquine; Drug Resistance; Gene Dosage; Gene Editin | 2018 |
Reversal of mefloquine and quinine resistance in Plasmodium falciparum with NP30.
Topics: Animals; Antimalarials; Calcium Channel Blockers; Drug Resistance; Genotype; Humans; Malaria, Falcip | 2003 |
pfcrt Allelic types with two novel amino acid mutations in chloroquine-resistant Plasmodium falciparum isolates from the Philippines.
Topics: Alleles; Amino Acid Substitution; Amino Acids; Animals; Antimalarials; Calcium Channel Blockers; Chl | 2003 |
Chemosensitizing action of cepharanthine against drug-resistant human malaria, Plasmodium falciparum.
Topics: Alkaloids; Animals; Benzylisoquinolines; Chloroquine; Disease Models, Animal; Dose-Response Relation | 2005 |
Relationship of global chloroquine transport and reversal of resistance in Plasmodium falciparum.
Topics: Animals; Biological Transport, Active; Chloroquine; Desipramine; Drug Resistance; Humans; Hydrogen-I | 1994 |
Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys.
Topics: Animals; Aotus trivirgatus; Calcium Channel Blockers; Chloroquine; Chlorpromazine; Cyproheptadine; D | 1993 |
Synergy between two calcium channel blockers, verapamil and fantofarone (SR33557), in reversing chloroquine resistance in Plasmodium falciparum.
Topics: Animals; Antimalarials; Calcium Channel Blockers; Chloroquine; Dose-Response Relationship, Drug; Dru | 1998 |
Phenotypic and genotypic characteristics of recently adapted isolates of Plasmodium falciparum from Thailand.
Topics: Animals; Antimalarials; Blotting, Western; Chloroquine; DNA Fingerprinting; DNA, Protozoan; Drug Res | 1999 |
Reversal activity of the naturally occurring chemosensitizer malagashanine in Plasmodium malaria.
Topics: Alkaloids; Animals; Antimalarials; Chloroquine; Disease Models, Animal; Drug Interactions; Drug Resi | 2000 |