verapamil has been researched along with Lung Diseases, Obstructive in 22 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Evaluation of efficacy of intravenous flecainide to revert supraventricular arrhythmias to sinus rhythm in patients with respiratory insufficiency." | 9.07 | Efficacy of flecainide in patients with supraventricular arrhythmias and respiratory insufficiency. ( Barranco, F; Guerrero, M; Rodriguez, J; Sanchez, M, 1994) |
| "Verapamil was devoid of any such effect." | 6.66 | Evaluation of verapamil in the treatment of hypertension. ( Anavekar, SN; Doyle, AE, 1986) |
| "Sinus tachycardia is an expected physiologic response to endogenous catecholamine stimulation, although it may limit the use of exogenous agents." | 5.27 | Use of verapamil to control an inappropriate chronic sinus tachycardia. ( Foster, MC; Levine, PA, 1984) |
| "Evaluation of efficacy of intravenous flecainide to revert supraventricular arrhythmias to sinus rhythm in patients with respiratory insufficiency." | 5.07 | Efficacy of flecainide in patients with supraventricular arrhythmias and respiratory insufficiency. ( Barranco, F; Guerrero, M; Rodriguez, J; Sanchez, M, 1994) |
| " Biochemical evidence suggests that pulmonary vasoconstriction results from the transmembrane flux of calcium into vascular smooth muscle; accordingly, the pulmonary pressor responses in experimental hypoxic pulmonary hypertension can be attenuated by verapamil and nifedipine." | 4.77 | Therapeutic application of calcium-channel antagonists for pulmonary hypertension. ( Packer, M, 1985) |
| "Verapamil was devoid of any such effect." | 2.66 | Evaluation of verapamil in the treatment of hypertension. ( Anavekar, SN; Doyle, AE, 1986) |
| "Verapamil was devoid of any such effect." | 2.65 | A double-blind comparison of verapamil and labetalol in hypertensive patients with coexisting chronic obstructive airways disease. ( Adam, WR; Anavekar, SN; Barter, C; Doyle, AE, 1982) |
| " No clinically useful benefit was found with verapamil in the dosage used in this group of patients and the value of calcium antagonists in the treatment of patients with chronic obstructive lung disease requires further clarification." | 1.27 | Effects of verapamil on pulmonary haemodynamics during hypoxaemia, at rest, and during exercise in patients with chronic obstructive pulmonary disease. ( Blair, GP; Brown, SE; King, RR; Light, RW; Linden, GS; Stansbury, DW, 1983) |
| "Sinus tachycardia is an expected physiologic response to endogenous catecholamine stimulation, although it may limit the use of exogenous agents." | 1.27 | Use of verapamil to control an inappropriate chronic sinus tachycardia. ( Foster, MC; Levine, PA, 1984) |
| "Verapamil hydrochloride was added to each theophylline solution to produce final verapamil concentrations of 0." | 1.27 | Compatibility of premixed theophylline and verapamil intravenous admixtures. ( Aviles, AI; Johnson, CE; Lloyd, CW; Rybarz, KL, 1988) |
| "Arrhythmia recurrence appeared to be dependent on reaching a critical but "nontoxic" serum theophylline concentration in the presence of high normal levels of digoxin." | 1.27 | Atrial arrhythmias exacerbated by theophylline. Response to verapamil and evidence for triggered activity in man. ( Marchlinski, FE; Miller, JM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (77.27) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anavekar, SN | 2 |
| Barter, C | 1 |
| Adam, WR | 1 |
| Doyle, AE | 2 |
| Burgersdijk, C | 1 |
| van der Meer, FJ | 1 |
| van der Vijver, JC | 1 |
| Brown, SE | 1 |
| Linden, GS | 1 |
| King, RR | 1 |
| Blair, GP | 1 |
| Stansbury, DW | 1 |
| Light, RW | 1 |
| Khadzhipetrov, N | 1 |
| Georgiev, S | 1 |
| Foster, MC | 1 |
| Levine, PA | 1 |
| Lara, PF | 1 |
| Hueb, WA | 1 |
| Sclavo, M | 1 |
| Bucca, C | 1 |
| Rolla, G | 1 |
| Borello, G | 1 |
| Balbi, L | 1 |
| Angelino, PF | 1 |
| Barranco, F | 1 |
| Sanchez, M | 1 |
| Rodriguez, J | 1 |
| Guerrero, M | 1 |
| Kaeser, YA | 1 |
| Brunner, F | 1 |
| Drewe, J | 1 |
| Haefeli, WE | 1 |
| Broeders, ME | 1 |
| Heijdra, YF | 1 |
| Smits, P | 1 |
| Folgering, HT | 1 |
| Kramers, C | 1 |
| Siergiejko, Z | 1 |
| Kazberuk, M | 1 |
| Hofman, J | 1 |
| Chyrek-Borowska, S | 1 |
| Gassner, A | 1 |
| Sommer, G | 1 |
| Fridrich, L | 1 |
| Magometschnigg, D | 1 |
| Priol, A | 1 |
| Ahmed, T | 1 |
| Abraham, WM | 1 |
| Berman, BA | 1 |
| Ross, RN | 1 |
| Schauer, J | 1 |
| Himmel, W | 1 |
| Orschekowski, H | 1 |
| Chen, PH | 1 |
| Johnson, CE | 1 |
| Lloyd, CW | 1 |
| Aviles, AI | 1 |
| Rybarz, KL | 1 |
| Treacher, DF | 1 |
| Douglas, A | 1 |
| Jones, A | 1 |
| Bateman, NT | 1 |
| Bradley, RD | 1 |
| Cameron, IR | 1 |
| Packer, M | 1 |
| Marchlinski, FE | 1 |
| Miller, JM | 1 |
3 reviews available for verapamil and Lung Diseases, Obstructive
| Article | Year |
|---|---|
Role of calcium-channel blockers in obstructive airway disease.
Topics: Acetylcholine; Animals; Asthma; Asthma, Exercise-Induced; Calcium; Calcium Channel Blockers; Diltiaz | 1985 |
Treating coexisting cardiovascular and pulmonary disease with calcium antagonists.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Asthma, Exercise-Induced; Bronchial Spasm; Calcium; Ca | 1986 |
Therapeutic application of calcium-channel antagonists for pulmonary hypertension.
Topics: Animals; Calcium Channel Blockers; Cattle; Diltiazem; Hemodynamics; Humans; Hypertension, Pulmonary; | 1985 |
5 trials available for verapamil and Lung Diseases, Obstructive
| Article | Year |
|---|---|
A double-blind comparison of verapamil and labetalol in hypertensive patients with coexisting chronic obstructive airways disease.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Ethan | 1982 |
Efficacy of flecainide in patients with supraventricular arrhythmias and respiratory insufficiency.
Topics: Acute Disease; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Chi-Square Distribution; Electrocardio | 1994 |
Verapamil causes decreased diaphragm endurance but no decrease of nocturnal O(2) saturation in patients with chronic obstructive pulmonary disease.
Topics: Aged; Blood Gas Analysis; Calcium Channel Blockers; Circadian Rhythm; Cross-Over Studies; Diaphragm; | 2000 |
[Modification of pulmonary hypertension in patients with chronic obstructive lung diseases using calcium antagonists in an acute trial].
Topics: Administration, Sublingual; Adult; Aged; Clinical Trials as Topic; Humans; Hypertension, Pulmonary; | 1989 |
Evaluation of verapamil in the treatment of hypertension.
Topics: Adult; Benzothiadiazines; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; He | 1986 |
14 other studies available for verapamil and Lung Diseases, Obstructive
| Article | Year |
|---|---|
Effects of metoprolol on digitalis-resistant atrial tachyarrhythmias in chronic obstructive pulmonary disease.
Topics: Aged; Digitalis; Drug Therapy, Combination; Female; Heart Rate; Humans; Lung Diseases, Obstructive; | 1984 |
Effects of verapamil on pulmonary haemodynamics during hypoxaemia, at rest, and during exercise in patients with chronic obstructive pulmonary disease.
Topics: Aged; Blood Pressure; Hemodynamics; Humans; Hypoxia; Lung Diseases, Obstructive; Middle Aged; Physic | 1983 |
[Use of Falicard and Sectral in patients with COPD and ischemic heart disease].
Topics: Angina Pectoris; Atenolol; Coronary Disease; Drug Evaluation; Drug Therapy, Combination; Humans; Lun | 1983 |
Calcium channel blocking agents. Council on scientific affairs.
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Asthma; Calcium Channel Blockers; Cardiomyopathy, Hy | 1983 |
Use of verapamil to control an inappropriate chronic sinus tachycardia.
Topics: Aged; Female; Humans; Lung Diseases, Obstructive; Tachycardia; Verapamil | 1984 |
[Measurements of cardio-angio-pulmonary indices, through radiocardiography, before and after the use of verapamil, by oral route, in patients with chronic obstructive lung disease].
Topics: Female; Humans; Lung Diseases, Obstructive; Male; Pulmonary Circulation; Radiography; Verapamil; Vit | 1982 |
[Pulmonary hypertension in chronic obstructive lung disease. Hemodynamic changes induced by oxygen, verapamil, and isoproterenol acute administration (author's transl)].
Topics: Aged; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Isoproterenol; Lung Diseases, Obstructi | 1981 |
Severe hypotension and bradycardia associated with verapamil and clarithromycin.
Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Bradycardia; Clarithromycin; Drug Interactions; Femal | 1998 |
[Influence of muscarinic receptors and calcium channel blockers on bronchial reactivity and ventilation parameters in patients with obstructive lung diseases].
Topics: Bronchial Hyperreactivity; Humans; Ipratropium; Lung Diseases, Obstructive; Respiratory Function Tes | 1991 |
Differential therapy with calcium antagonists in pulmonary hypertension secondary to COPD. Hemodynamic effects of nifedipine, diltiazem, and verapamil.
Topics: Calcium Channel Blockers; Diltiazem; Exercise Test; Hemodynamics; Humans; Hypertension, Pulmonary; L | 1990 |
Multiform atrial tachycardia.
Topics: Aged; Carcinoma, Small Cell; Heart Atria; Humans; Lung Diseases, Obstructive; Lung Neoplasms; Male; | 1986 |
Compatibility of premixed theophylline and verapamil intravenous admixtures.
Topics: Chromatography, High Pressure Liquid; Drug Combinations; Drug Incompatibility; Drug Stability; Human | 1988 |
The acute haemodynamic effects of intravenous verapamil in patients with chronic obstructive airways disease.
Topics: Acute Disease; Cardiac Output; Female; Hemodynamics; Humans; Hypoxia; Infusions, Intravenous; Lung D | 1987 |
Atrial arrhythmias exacerbated by theophylline. Response to verapamil and evidence for triggered activity in man.
Topics: Aged; Digoxin; Electrocardiography; Female; Heart Atria; Humans; Lung Diseases, Obstructive; Recurre | 1985 |