Page last updated: 2024-10-24

verapamil and Leukemia, Promyelocytic, Acute

verapamil has been researched along with Leukemia, Promyelocytic, Acute in 8 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.

Research Excerpts

ExcerptRelevanceReference
" Although apoptosis occurred when its multidrugs resistance had been reversed by verapamil, compared with sensitive HL-60 cells, the time at which apoptosis happened delayed and the drug dosage increased."1.29[Apoptosis resistance and its reversal in harringtonine resistant cell line]. ( Chi, XS; Fang, M; Pang, DB; Xue, SB; Zhang, HQ, 1994)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's7 (87.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frey, T1
Yue, S1
Haugland, RP1
Fang, M1
Zhang, HQ2
Xue, SB2
Pang, DB1
Chi, XS1
Su, GM1
Davey, MW2
Davey, RA2
Kidman, AD1
Maslak, P1
Hegewisch-Becker, S1
Godfrey, L1
Andreeff, M1
Kizaki, M1
Ueno, H1
Yamazoe, Y1
Shimada, M1
Takayama, N1
Muto, A1
Matsushita, H1
Nakajima, H1
Morikawa, M1
Koeffler, HP1
Ikeda, Y1
Mote, PA1
Oliver, L1
Wang, L1
Wang, RH1
He, NG1
Cass, CE1
Janowska-Wieczorek, A1
Lynch, MA1
Sheinin, H1
Hindenburg, AA1
Beck, WT1

Other Studies

8 other studies available for verapamil and Leukemia, Promyelocytic, Acute

ArticleYear
Dyes providing increased sensitivity in flow-cytometric dye-efflux assays for multidrug resistance.
    Cytometry, 1995, Jul-01, Volume: 20, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Burkitt Lymphoma; Calcium Channel

1995
[Apoptosis resistance and its reversal in harringtonine resistant cell line].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1994, Volume: 29, Issue:12

    Topics: Apoptosis; Drug Resistance, Multiple; Harringtonines; Humans; Leukemia, Promyelocytic, Acute; Tumor

1994
Development of extended multidrug resistance in HL60 promyelocytic leukaemia cells.
    British journal of haematology, 1994, Volume: 88, Issue:3

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine

1994
Flow cytometric determination of the multidrug-resistant phenotype in acute leukemia.
    Cytometry, 1994, Sep-01, Volume: 17, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemoth

1994
Mechanisms of retinoid resistance in leukemic cells: possible role of cytochrome P450 and P-glycoprotein.
    Blood, 1996, Jan-15, Volume: 87, Issue:2

    Topics: Antigens, Differentiation; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamil

1996
Paclitaxel sensitizes multidrug resistant cells to radiation.
    Anti-cancer drugs, 1996, Volume: 7, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Death; Dose-Response Relationship, Drug; Drug Re

1996
[Enhancement of antitumor activity of harringtonine in human leukemia-60 cells in vitro by verapamil].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:5

    Topics: Antineoplastic Agents; Drug Synergism; Harringtonines; Humans; Leukemia, Promyelocytic, Acute; Tumor

1992
Effect of duration of exposure to verapamil on vincristine activity against multidrug-resistant human leukemic cell lines.
    Cancer research, 1989, Nov-01, Volume: 49, Issue:21

    Topics: Cell Division; Cell Line; Drug Resistance; Humans; Kinetics; Leukemia, Lymphoid; Leukemia, Promyeloc

1989