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verapamil and Leukemia, Myeloid, Acute

verapamil has been researched along with Leukemia, Myeloid, Acute in 44 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research Excerpts

ExcerptRelevanceReference
"The in vitro effect of the dextroisomer r-verapamil on blast cells derived from patients with acute myelogenous leukemia (AML) was studied."7.69In vitro effect of r-verapamil on acute myelogenous leukemia blast cells: studies of cytokine secretion and cytokine-dependent blast proliferation. ( Bruserud, O; Nesthus, I; Pawelec, G, 1995)
"We investigated the effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocytes were activated in the presence of accessory cells containing a large population of acute myelogenous leukemia (AML) blasts (nonirradiated blasts for cytokine studies, 50 Gy irradiated blasts in proliferation studies)."7.69In vitro effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocyte activation takes place in the presence of acute myelogenous leukemia blasts. ( Bruserud, O, 1996)
"Pharmacokinetic studies were performed in 27 patients with a diagnosis of acute myelogenous leukemia (AML), who were being treated with a combination chemotherapy regimen including idarubicin and cytarabine for the induction of a first remission (n = 14), or of a second remission (n = 7), or for remission consolidation (n = 6)."3.70Multidrug resistance modulation in vivo: the effect of cyclosporin A alone or with dexverapamil on idarubicin pharmacokinetics in acute leukemia. ( Baccarani, M; Baraldo, M; Damiani, D; Ermacora, A; Fanin, R; Furlanut, M; Michieli, M; Pea, F; Russo, D, 1999)
"The in vitro effect of the dextroisomer r-verapamil on blast cells derived from patients with acute myelogenous leukemia (AML) was studied."3.69In vitro effect of r-verapamil on acute myelogenous leukemia blast cells: studies of cytokine secretion and cytokine-dependent blast proliferation. ( Bruserud, O; Nesthus, I; Pawelec, G, 1995)
"We investigated the effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocytes were activated in the presence of accessory cells containing a large population of acute myelogenous leukemia (AML) blasts (nonirradiated blasts for cytokine studies, 50 Gy irradiated blasts in proliferation studies)."3.69In vitro effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocyte activation takes place in the presence of acute myelogenous leukemia blasts. ( Bruserud, O, 1996)
"Dipyridamole strongly inhibited spontaneous in vitro proliferation of peripheral blood mononuclear cells from patients with acute myelogenous leukaemia (n = 9), chronic myelogenous leukaemia in first chronic phase (n = 4) and blast phase (n = 1)."3.68Effect of dipyridamole, theophyllamine and verapamil on spontaneous in vitro proliferation of myelogenous leukaemia cells. ( Bruserud, O, 1992)
"In the following study, patients with acute myeloid leukemia (AML) treated with double induction and consolidation chemotherapy (AML COOP study 1986, [3]) were randomized in a group with and without accompanying low-dose oral verapamil treatment."2.67Effects of verapamil on anthracycline-induced cardiomyopathy: preliminary results of a prospective multicenter trial. ( Appelt, M; Büchner, T; Eichelbaum, M; Grille, W; Hiddemann, W; Hossfeld, DK; Koslowski, B; Kraft, J; Kuse, R; Quabeck, K, 1990)
"Also in acute myeloid leukemia (AML), the proliferation rate (percentage S/G(2)+M and Iododeoxyuridine labelings index) was significantly less in the RhoD blasts (P 1.30Triggering noncycling hematopoietic progenitors and leukemic blasts to proliferate increases anthracycline retention and toxicity by downregulating multidrug resistance. ( de Witte, T; Pennings, AH; Raymakers, RA; Smeets, ME; Vierwinden, G; Wessels, H, 1999)
"Forty one patients with acute myeloid leukemia (AML), including 27 at presentation and 14 relapsed or resistant cases, were assessed for laboratory evidence of the MDR phenotype."1.29Flow cytometric assessment of multidrug resistance (MDR) phenotype in acute myeloid leukaemia. ( Ganeshaguru, K; Hart, SM; Hoffbrand, AV; Lyttelton, MP; Mehta, AB; Prentice, HG, 1993)
"Pgp was positive in 75% of acute nonlymphoblastic leukemia (ANLL) and 50% of acute lymphoblastic leukemia (ALL)."1.28P-glycoprotein expression in refractory hematological neoplasms and circumvention of resistance with verapamil or cyclosporine A containing protocols. ( Akan, H; Beksaç, M; Ertürk, S; Güneyli, A; Ikizünal, Y; Ilhan, O; Koç, H; Sardaş, OS, 1992)
"The vinblastine-resistant human lymphoblastic leukemia cell line CEM-VBL demonstrated minimal DNR uptake; simultaneous incubation with verapamil and DNR increased intracellular DNR uptake fourfold."1.28Comparative cellular pharmacology of daunorubicin and idarubicin in human multidrug-resistant leukemia cells. ( Berman, E; McBride, M, 1992)
"Cytochalasin B was most effective in VCR- and DAU-sensitive cells; however, the effect in resistant cells was less than that observed for verapamil, suggesting a different mode of action between these drugs in sensitive and resistant cells."1.27Effects of cytochalasins and colchicine on the accumulation and retention of daunomycin and vincristine in drug resistant tumor cells. ( Iida, H; Tsuruo, T, 1986)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19909 (20.45)18.7374
1990's28 (63.64)18.2507
2000's7 (15.91)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, CH2
Kim, JH1
Kim, SH1
Li, GY1
Liu, JZ1
Zhang, B1
Wang, LX1
Wang, CB1
Chen, SG1
Takeshita, A1
Biscardi, M1
Teodori, E1
Caporale, R1
Budriesi, R1
Balestri, F1
Scappini, B1
Gavazzi, S1
Grossi, A1
Sikic, BI1
Raaijmakers, MH1
de Grouw, EP1
van der Reijden, BA1
de Witte, TJ1
Jansen, JH1
Raymakers, RA2
Bruserud, O4
Nesthus, I1
Pawelec, G2
Marie, JP2
Zhou, D1
Delmer, A2
Zittoun, R2
Hart, SM1
Ganeshaguru, K1
Lyttelton, MP1
Prentice, HG1
Hoffbrand, AV1
Mehta, AB1
Mukhammed, A1
Turkina, AG1
Al'pidovskiĭ, VK1
Sidorova, TA1
Golenko, OD1
Gerasimova, GK1
Raghu, G1
Pierre-Jerome, M1
Dordal, MS1
Simonian, P1
Bauer, KD1
Winter, JN1
Ross, DD1
Wooten, PJ1
Sridhara, R1
Ordóñez, JV1
Lee, EJ1
Schiffer, CA1
Boiron, JM1
Belloc, F1
Montastruc, M1
Cony-Makhoul, P1
Dumain, P1
Marit, G1
Mahon, FX1
Puntous, M1
Lopez, F1
Lacombe, F1
Visani, G1
Fogli, M1
Tosi, P1
Ottaviani, E1
Gamberi, B1
Cenacchi, A1
Manfroi, S1
Tura, S1
Quillet-Mary, A1
Mansat, V1
Duchayne, E1
Come, MG1
Allouche, M1
Bailly, JD1
Bordier, C1
Laurent, G1
Pirker, R1
Zöchbauer, S1
Kupper, H1
Lassmann, A1
Gsur, A1
Frass, M1
Krajnik, G1
Knöbl, P1
Lechner, K1
Beck, JF1
Buchholz, F1
Ulrich, WR1
Boer, R1
Sanders, KH1
Niethammer, D1
Gekeler, V1
Kim, HS1
Rha, HS1
Jeong, JH1
Park, YH1
Min, YD1
Kee, KH1
Lim, DY1
Pea, F1
Damiani, D1
Michieli, M1
Ermacora, A1
Baraldo, M1
Russo, D1
Fanin, R1
Baccarani, M1
Furlanut, M1
Smeets, ME1
Vierwinden, G1
Pennings, AH1
Wessels, H1
de Witte, T1
De Moerloose, B1
Dhooge, C1
Philippé, J1
Schröder, JK1
Kasimir-Bauer, S1
Seeber, S2
Scheulen, ME1
Helou, C1
Thevenin, D1
Léonce, S1
Pierré, A1
Anstett, M1
Pérez, V1
Genton, A1
Bizzari, JP1
Atassi, G1
Müller, MR1
Lennartz, K1
Boogen, C1
Nowrousian, MR1
Rajewsky, MF1
Beksaç, M1
Akan, H1
Koç, H1
Ilhan, O1
Ertürk, S1
Güneyli, A1
Ikizünal, Y1
Sardaş, OS1
Berman, E2
McBride, M1
Solary, E2
Bidan, JM2
Calvo, F1
Chauffert, B2
Caillot, D2
Mugneret, F1
Gauville, C1
Tsuruo, T2
Carli, PM1
Guy, H2
Velay, I1
Dumas, M1
Nooter, K1
Sonneveld, P1
Oostrum, R1
Herweijer, H1
Hagenbeek, T1
Valerio, D1
Adams, M1
Duigou-Osterndorf, R1
Godfrey, L1
Clarkson, B1
Andreeff, M1
Kraft, J1
Grille, W1
Appelt, M1
Hossfeld, DK1
Eichelbaum, M1
Koslowski, B1
Quabeck, K1
Kuse, R1
Büchner, T1
Hiddemann, W1
McGrath, T1
Latoud, C1
Arnold, ST1
Safa, AR1
Felsted, RL1
Center, MS1
Maruyama, Y1
Murohashi, I1
Nara, N1
Aoki, N1
Rephaeli, A1
Aviram, A1
Englender, T1
Shaklai, M1
Yen, A1
Freeman, L1
Powers, V1
Van Sant, R1
Fishbaugh, J1
Levy, R1
Nathan, I1
Barnea, E1
Chaimovitz, C1
Shany, S1
Iida, H1
Okazaki, T1
Mochizuki, T1
Tashima, M1
Sawada, H1
Uchino, H1
Hindenburg, AA1
Baker, MA1
Gleyzer, E1
Stewart, VJ1
Case, N1
Taub, RN2
Bhalla, K1
Hindenburg, A1
Grant, S1

Reviews

3 reviews available for verapamil and Leukemia, Myeloid, Acute

ArticleYear
[Recent advances in the treatment of acute myelogenous leukemia: a view of the new agents].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2003, Volume: 44, Issue:12

    Topics: Alkyl and Aryl Transferases; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humani

2003
Multidrug resistance and stem cells in acute myeloid leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jun-01, Volume: 12, Issue:11 Pt 1

    Topics: ADP-ribosyl Cyclase 1; Antigens, CD34; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Ca

2006
[Trials of modulating the MDR1 phenotype in malignant hemopathies].
    Bulletin du cancer, 1994, Volume: 81 Suppl 2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Dexamethasone; Doxorubicin; D

1994

Trials

3 trials available for verapamil and Leukemia, Myeloid, Acute

ArticleYear
Cyclosporine diminishes multidrug resistance in K562/ADM cells and improves complete remission in patients with acute myeloid leukemia.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2009, Volume: 63, Issue:8

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cass

2009
[Trials of modulating the MDR1 phenotype in malignant hemopathies].
    Bulletin du cancer, 1994, Volume: 81 Suppl 2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Dexamethasone; Doxorubicin; D

1994
Effects of verapamil on anthracycline-induced cardiomyopathy: preliminary results of a prospective multicenter trial.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cytarabine; Dau

1990

Other Studies

39 other studies available for verapamil and Leukemia, Myeloid, Acute

ArticleYear
Reversal of P-glycoprotein-mediated MDR by 5,7,3',4',5'-pentamethoxyflavone and SAR.
    Biochemical and biophysical research communications, 2004, Jul-30, Volume: 320, Issue:3

    Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor

2004
Multidrug reverting activity toward leukemia cells in a group of new verapamil analogues with low cardiovascular activity.
    Leukemia research, 2006, Volume: 30, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Anti-Arrhythmia Agents; Antibiotics, Antineoplastic; Aorta;

2006
ABCB1 modulation does not circumvent drug extrusion from primitive leukemic progenitor cells and may preferentially target residual normal cells in acute myelogenous leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jun-01, Volume: 12, Issue:11 Pt 1

    Topics: Adolescent; ADP-ribosyl Cyclase 1; Adult; Aged; Antigens, CD34; Antigens, Differentiation; ATP Bindi

2006
In vitro effect of r-verapamil on acute myelogenous leukemia blast cells: studies of cytokine secretion and cytokine-dependent blast proliferation.
    Cancer chemotherapy and pharmacology, 1995, Volume: 37, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Cell Division; Cytokines; Fema

1995
Effects of dipyridamole and R-verapamil on in vitro proliferation of blast cells from patients with acute myelogenous leukaemia.
    Leukemia research, 1993, Volume: 17, Issue:6

    Topics: Adult; Aged; Blast Crisis; Cell Division; Dipyridamole; Dose-Response Relationship, Drug; Female; Gr

1993
Flow cytometric assessment of multidrug resistance (MDR) phenotype in acute myeloid leukaemia.
    Leukemia & lymphoma, 1993, Volume: 11, Issue:3-4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1;

1993
[The use of verapamil in tests for determining the drug resistance of leukemic blasts].
    Gematologiia i transfuziologiia, 1993, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Aged; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloi

1993
P-glycoprotein and alterations in the glutathione/glutathione-peroxidase cycle underlie doxorubicin resistance in HL-60-R, a subclone of the HL-60 human leukemia cell line.
    International journal of cancer, 1993, Mar-12, Volume: 53, Issue:5

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine

1993
Enhancement of daunorubicin accumulation, retention, and cytotoxicity by verapamil or cyclosporin A in blast cells from patients with previously untreated acute myeloid leukemia.
    Blood, 1993, Aug-15, Volume: 82, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, W

1993
Flow cytometric study of idarubicin and daunorubicin accumulation and the effect of verapamil in leukemic cell lines and fresh cells from patients with acute non-lymphoblastic leukemia.
    Leukemia research, 1994, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Daunorubicin; Drug Resistance; Female; Flow Cytometry; Humans; Idarubicin; Leukem

1994
Comparative effects of racemic verapamil vs R-verapamil on normal and leukemic progenitors.
    Annals of hematology, 1993, Volume: 66, Issue:6

    Topics: Bone Marrow Cells; Colony-Forming Units Assay; Daunorubicin; Drug Therapy, Combination; Erythroid Pr

1993
Daunorubicin-induced internucleosomal DNA fragmentation in acute myeloid cell lines.
    Leukemia, 1996, Volume: 10, Issue:3

    Topics: Acetylcysteine; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; ATP Binding Cassette Transport

1996
Dexverapamil as resistance modifier in acute myeloid leukaemia.
    Journal of cancer research and clinical oncology, 1995, Volume: 121 Suppl 3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfa

1995
In vitro effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocyte activation takes place in the presence of acute myelogenous leukemia blasts.
    Cancer chemotherapy and pharmacology, 1996, Volume: 39, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Female; Granulocyte Colony-Stimulating Fac

1996
Rhodamine 123 efflux modulation in the presence of low or high serum from CD56+ hematopoietic cells or CD34+ leukemic blasts by B9309-068, a newly designed pyridine derivative.
    Cancer letters, 1998, Jul-17, Volume: 129, Issue:2

    Topics: Acridines; Antigens, CD34; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cass

1998
Drug concentration-dependent expression of multidrug resistance-associated protein and P-glycoprotein in the doxorubicin-resistant acute myelogenous leukemia sublines.
    Molecules and cells, 1999, Jun-30, Volume: 9, Issue:3

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette

1999
Multidrug resistance modulation in vivo: the effect of cyclosporin A alone or with dexverapamil on idarubicin pharmacokinetics in acute leukemia.
    European journal of clinical pharmacology, 1999, Volume: 55, Issue:5

    Topics: Cyclosporine; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Idarubicin; Leukemia, My

1999
Triggering noncycling hematopoietic progenitors and leukemic blasts to proliferate increases anthracycline retention and toxicity by downregulating multidrug resistance.
    Blood, 1999, Oct-01, Volume: 94, Issue:7

    Topics: Antibiotics, Antineoplastic; Antigens, CD34; ATP Binding Cassette Transporter, Subfamily B, Member 1

1999
Discordance of P-glycoprotein expression and function in acute leukemia.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Adolescent; Adult; Age Factors; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow

1999
In vitro effect of multidrug resistance modifiers on idarubicinol efflux in blasts of acute myeloid leukemia.
    Journal of cancer research and clinical oncology, 2000, Volume: 126, Issue:2

    Topics: Antineoplastic Agents; Blast Crisis; Calcium Channel Blockers; Daunorubicin; Dihydropyridines; Drug

2000
In vitro effect of P-glycoprotein (P-gp) modulators on drug sensitivity of leukemic progenitors (CFU-L) in acute myelogenous leukemia (AML).
    Experimental hematology, 1992, Volume: 20, Issue:5

    Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cefoperazone; Cyclosporine; Daunorub

1992
Effects of a new triazinoaminopiperidine derivative on adriamycin accumulation and retention in cells displaying P-glycoprotein-mediated multidrug resistance.
    Biochemical pharmacology, 1992, Nov-03, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Membe

1992
Cytotoxicity of adriamycin, idarubicin, and vincristine in acute myeloid leukemia: chemosensitization by verapamil in relation to P-glycoprotein expression.
    Annals of hematology, 1992, Volume: 65, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Membe

1992
P-glycoprotein expression in refractory hematological neoplasms and circumvention of resistance with verapamil or cyclosporine A containing protocols.
    Medical oncology and tumor pharmacotherapy, 1992, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter,

1992
Effect of dipyridamole, theophyllamine and verapamil on spontaneous in vitro proliferation of myelogenous leukaemia cells.
    Acta oncologica (Stockholm, Sweden), 1992, Volume: 31, Issue:1

    Topics: Aminophylline; Blast Crisis; Cell Division; Dipyridamole; Dose-Response Relationship, Drug; Drug Scr

1992
Comparative cellular pharmacology of daunorubicin and idarubicin in human multidrug-resistant leukemia cells.
    Blood, 1992, Jun-15, Volume: 79, Issue:12

    Topics: Cell Division; Daunorubicin; Drug Resistance; Humans; Idarubicin; Leukemia, Myeloid, Acute; Precurso

1992
P-glycoprotein expression and in vitro reversion of doxorubicin resistance by verapamil in clinical specimens from acute leukaemia and myeloma.
    Leukemia, 1991, Volume: 5, Issue:7

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Resistance; Humans; Leuke

1991
Sufficient levels of quinine in the serum circumvent the multidrug resistance of the human leukemic cell line K562/ADM.
    Cancer, 1991, Oct-15, Volume: 68, Issue:8

    Topics: Doxorubicin; Drug Resistance; Feasibility Studies; Humans; Leukemia; Leukemia, Myeloid, Acute; Multi

1991
Overexpression of the mdr1 gene in blast cells from patients with acute myelocytic leukemia is associated with decreased anthracycline accumulation that can be restored by cyclosporin-A.
    International journal of cancer, 1990, Feb-15, Volume: 45, Issue:2

    Topics: Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporins; Daun

1990
Effect of tamoxifen on cell lines displaying the multidrug-resistant phenotype.
    Blood, 1991, Feb-15, Volume: 77, Issue:4

    Topics: Cell Division; Daunorubicin; Drug Resistance; Flow Cytometry; Humans; Kinetics; Leukemia, Lymphoid;

1991
Mechanisms of multidrug resistance in HL60 cells. Analysis of resistance associated membrane proteins and levels of mdr gene expression.
    Biochemical pharmacology, 1989, Oct-15, Volume: 38, Issue:20

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Resistance; Gene Amplific

1989
Effects of verapamil on the cellular accumulation of daunorubicin in blast cells and on the chemosensitivity of leukaemic blast progenitors in acute myelogenous leukaemia.
    British journal of haematology, 1989, Volume: 72, Issue:3

    Topics: Adult; Aged; Cell Survival; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia

1989
Differentiation-associated changes of cation-transport activities in myeloid leukemic cell lines.
    FEBS letters, 1988, Aug-29, Volume: 236, Issue:2

    Topics: Amiloride; Biological Transport; Calcium; Carrier Proteins; Cell Differentiation; Cromolyn Sodium; H

1988
Cell cycle dependence of calmodulin levels during HL-60 proliferation and myeloid differentiation. No changes during pre-commitment.
    Experimental cell research, 1986, Volume: 165, Issue:1

    Topics: Calmodulin; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Humans; Leukemia, Myeloid, A

1986
The involvement of calcium ions in the effect of 1,25-dihydroxyvitamin D3 on HL-60 cells.
    Experimental hematology, 1988, Volume: 16, Issue:4

    Topics: Calcitriol; Calcium; Cell Differentiation; Cell Line; Cytosol; Egtazic Acid; Growth Inhibitors; Huma

1988
Effects of cytochalasins and colchicine on the accumulation and retention of daunomycin and vincristine in drug resistant tumor cells.
    Biochemical pharmacology, 1986, Apr-01, Volume: 35, Issue:7

    Topics: Animals; Cell Line; Cell Survival; Colchicine; Cytochalasin B; Cytochalasin D; Cytochalasins; Daunor

1986
Role of intracellular calcium ion in human promyelocytic leukemia HL-60 cell differentiation.
    Cancer research, 1986, Volume: 46, Issue:12 Pt 1

    Topics: Calcitriol; Calcium; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Ethers; Gal

1986
Effect of verapamil and other agents on the distribution of anthracyclines and on reversal of drug resistance.
    Cancer research, 1987, Mar-01, Volume: 47, Issue:5

    Topics: Antibiotics, Antineoplastic; Cell Line; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Leukemia

1987
Isolation and characterization of an anthracycline-resistant human leukemic cell line.
    Cancer research, 1985, Volume: 45, Issue:8

    Topics: Antibiotics, Antineoplastic; Cell Differentiation; Cell Line; Drug Resistance; Glycoproteins; Humans

1985