verapamil has been researched along with Leukemia, Myeloid, Acute in 44 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The in vitro effect of the dextroisomer r-verapamil on blast cells derived from patients with acute myelogenous leukemia (AML) was studied." | 7.69 | In vitro effect of r-verapamil on acute myelogenous leukemia blast cells: studies of cytokine secretion and cytokine-dependent blast proliferation. ( Bruserud, O; Nesthus, I; Pawelec, G, 1995) |
| "We investigated the effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocytes were activated in the presence of accessory cells containing a large population of acute myelogenous leukemia (AML) blasts (nonirradiated blasts for cytokine studies, 50 Gy irradiated blasts in proliferation studies)." | 7.69 | In vitro effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocyte activation takes place in the presence of acute myelogenous leukemia blasts. ( Bruserud, O, 1996) |
| "Pharmacokinetic studies were performed in 27 patients with a diagnosis of acute myelogenous leukemia (AML), who were being treated with a combination chemotherapy regimen including idarubicin and cytarabine for the induction of a first remission (n = 14), or of a second remission (n = 7), or for remission consolidation (n = 6)." | 3.70 | Multidrug resistance modulation in vivo: the effect of cyclosporin A alone or with dexverapamil on idarubicin pharmacokinetics in acute leukemia. ( Baccarani, M; Baraldo, M; Damiani, D; Ermacora, A; Fanin, R; Furlanut, M; Michieli, M; Pea, F; Russo, D, 1999) |
| "The in vitro effect of the dextroisomer r-verapamil on blast cells derived from patients with acute myelogenous leukemia (AML) was studied." | 3.69 | In vitro effect of r-verapamil on acute myelogenous leukemia blast cells: studies of cytokine secretion and cytokine-dependent blast proliferation. ( Bruserud, O; Nesthus, I; Pawelec, G, 1995) |
| "We investigated the effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocytes were activated in the presence of accessory cells containing a large population of acute myelogenous leukemia (AML) blasts (nonirradiated blasts for cytokine studies, 50 Gy irradiated blasts in proliferation studies)." | 3.69 | In vitro effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocyte activation takes place in the presence of acute myelogenous leukemia blasts. ( Bruserud, O, 1996) |
| "Dipyridamole strongly inhibited spontaneous in vitro proliferation of peripheral blood mononuclear cells from patients with acute myelogenous leukaemia (n = 9), chronic myelogenous leukaemia in first chronic phase (n = 4) and blast phase (n = 1)." | 3.68 | Effect of dipyridamole, theophyllamine and verapamil on spontaneous in vitro proliferation of myelogenous leukaemia cells. ( Bruserud, O, 1992) |
| "In the following study, patients with acute myeloid leukemia (AML) treated with double induction and consolidation chemotherapy (AML COOP study 1986, [3]) were randomized in a group with and without accompanying low-dose oral verapamil treatment." | 2.67 | Effects of verapamil on anthracycline-induced cardiomyopathy: preliminary results of a prospective multicenter trial. ( Appelt, M; Büchner, T; Eichelbaum, M; Grille, W; Hiddemann, W; Hossfeld, DK; Koslowski, B; Kraft, J; Kuse, R; Quabeck, K, 1990) |
| "Also in acute myeloid leukemia (AML), the proliferation rate (percentage S/G(2)+M and Iododeoxyuridine labelings index) was significantly less in the RhoD blasts (P | 1.30 | Triggering noncycling hematopoietic progenitors and leukemic blasts to proliferate increases anthracycline retention and toxicity by downregulating multidrug resistance. ( de Witte, T; Pennings, AH; Raymakers, RA; Smeets, ME; Vierwinden, G; Wessels, H, 1999) |
| "Forty one patients with acute myeloid leukemia (AML), including 27 at presentation and 14 relapsed or resistant cases, were assessed for laboratory evidence of the MDR phenotype." | 1.29 | Flow cytometric assessment of multidrug resistance (MDR) phenotype in acute myeloid leukaemia. ( Ganeshaguru, K; Hart, SM; Hoffbrand, AV; Lyttelton, MP; Mehta, AB; Prentice, HG, 1993) |
| "Pgp was positive in 75% of acute nonlymphoblastic leukemia (ANLL) and 50% of acute lymphoblastic leukemia (ALL)." | 1.28 | P-glycoprotein expression in refractory hematological neoplasms and circumvention of resistance with verapamil or cyclosporine A containing protocols. ( Akan, H; Beksaç, M; Ertürk, S; Güneyli, A; Ikizünal, Y; Ilhan, O; Koç, H; Sardaş, OS, 1992) |
| "The vinblastine-resistant human lymphoblastic leukemia cell line CEM-VBL demonstrated minimal DNR uptake; simultaneous incubation with verapamil and DNR increased intracellular DNR uptake fourfold." | 1.28 | Comparative cellular pharmacology of daunorubicin and idarubicin in human multidrug-resistant leukemia cells. ( Berman, E; McBride, M, 1992) |
| "Cytochalasin B was most effective in VCR- and DAU-sensitive cells; however, the effect in resistant cells was less than that observed for verapamil, suggesting a different mode of action between these drugs in sensitive and resistant cells." | 1.27 | Effects of cytochalasins and colchicine on the accumulation and retention of daunomycin and vincristine in drug resistant tumor cells. ( Iida, H; Tsuruo, T, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (20.45) | 18.7374 |
| 1990's | 28 (63.64) | 18.2507 |
| 2000's | 7 (15.91) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, CH | 2 |
| Kim, JH | 1 |
| Kim, SH | 1 |
| Li, GY | 1 |
| Liu, JZ | 1 |
| Zhang, B | 1 |
| Wang, LX | 1 |
| Wang, CB | 1 |
| Chen, SG | 1 |
| Takeshita, A | 1 |
| Biscardi, M | 1 |
| Teodori, E | 1 |
| Caporale, R | 1 |
| Budriesi, R | 1 |
| Balestri, F | 1 |
| Scappini, B | 1 |
| Gavazzi, S | 1 |
| Grossi, A | 1 |
| Sikic, BI | 1 |
| Raaijmakers, MH | 1 |
| de Grouw, EP | 1 |
| van der Reijden, BA | 1 |
| de Witte, TJ | 1 |
| Jansen, JH | 1 |
| Raymakers, RA | 2 |
| Bruserud, O | 4 |
| Nesthus, I | 1 |
| Pawelec, G | 2 |
| Marie, JP | 2 |
| Zhou, D | 1 |
| Delmer, A | 2 |
| Zittoun, R | 2 |
| Hart, SM | 1 |
| Ganeshaguru, K | 1 |
| Lyttelton, MP | 1 |
| Prentice, HG | 1 |
| Hoffbrand, AV | 1 |
| Mehta, AB | 1 |
| Mukhammed, A | 1 |
| Turkina, AG | 1 |
| Al'pidovskiĭ, VK | 1 |
| Sidorova, TA | 1 |
| Golenko, OD | 1 |
| Gerasimova, GK | 1 |
| Raghu, G | 1 |
| Pierre-Jerome, M | 1 |
| Dordal, MS | 1 |
| Simonian, P | 1 |
| Bauer, KD | 1 |
| Winter, JN | 1 |
| Ross, DD | 1 |
| Wooten, PJ | 1 |
| Sridhara, R | 1 |
| Ordóñez, JV | 1 |
| Lee, EJ | 1 |
| Schiffer, CA | 1 |
| Boiron, JM | 1 |
| Belloc, F | 1 |
| Montastruc, M | 1 |
| Cony-Makhoul, P | 1 |
| Dumain, P | 1 |
| Marit, G | 1 |
| Mahon, FX | 1 |
| Puntous, M | 1 |
| Lopez, F | 1 |
| Lacombe, F | 1 |
| Visani, G | 1 |
| Fogli, M | 1 |
| Tosi, P | 1 |
| Ottaviani, E | 1 |
| Gamberi, B | 1 |
| Cenacchi, A | 1 |
| Manfroi, S | 1 |
| Tura, S | 1 |
| Quillet-Mary, A | 1 |
| Mansat, V | 1 |
| Duchayne, E | 1 |
| Come, MG | 1 |
| Allouche, M | 1 |
| Bailly, JD | 1 |
| Bordier, C | 1 |
| Laurent, G | 1 |
| Pirker, R | 1 |
| Zöchbauer, S | 1 |
| Kupper, H | 1 |
| Lassmann, A | 1 |
| Gsur, A | 1 |
| Frass, M | 1 |
| Krajnik, G | 1 |
| Knöbl, P | 1 |
| Lechner, K | 1 |
| Beck, JF | 1 |
| Buchholz, F | 1 |
| Ulrich, WR | 1 |
| Boer, R | 1 |
| Sanders, KH | 1 |
| Niethammer, D | 1 |
| Gekeler, V | 1 |
| Kim, HS | 1 |
| Rha, HS | 1 |
| Jeong, JH | 1 |
| Park, YH | 1 |
| Min, YD | 1 |
| Kee, KH | 1 |
| Lim, DY | 1 |
| Pea, F | 1 |
| Damiani, D | 1 |
| Michieli, M | 1 |
| Ermacora, A | 1 |
| Baraldo, M | 1 |
| Russo, D | 1 |
| Fanin, R | 1 |
| Baccarani, M | 1 |
| Furlanut, M | 1 |
| Smeets, ME | 1 |
| Vierwinden, G | 1 |
| Pennings, AH | 1 |
| Wessels, H | 1 |
| de Witte, T | 1 |
| De Moerloose, B | 1 |
| Dhooge, C | 1 |
| Philippé, J | 1 |
| Schröder, JK | 1 |
| Kasimir-Bauer, S | 1 |
| Seeber, S | 2 |
| Scheulen, ME | 1 |
| Helou, C | 1 |
| Thevenin, D | 1 |
| Léonce, S | 1 |
| Pierré, A | 1 |
| Anstett, M | 1 |
| Pérez, V | 1 |
| Genton, A | 1 |
| Bizzari, JP | 1 |
| Atassi, G | 1 |
| Müller, MR | 1 |
| Lennartz, K | 1 |
| Boogen, C | 1 |
| Nowrousian, MR | 1 |
| Rajewsky, MF | 1 |
| Beksaç, M | 1 |
| Akan, H | 1 |
| Koç, H | 1 |
| Ilhan, O | 1 |
| Ertürk, S | 1 |
| Güneyli, A | 1 |
| Ikizünal, Y | 1 |
| Sardaş, OS | 1 |
| Berman, E | 2 |
| McBride, M | 1 |
| Solary, E | 2 |
| Bidan, JM | 2 |
| Calvo, F | 1 |
| Chauffert, B | 2 |
| Caillot, D | 2 |
| Mugneret, F | 1 |
| Gauville, C | 1 |
| Tsuruo, T | 2 |
| Carli, PM | 1 |
| Guy, H | 2 |
| Velay, I | 1 |
| Dumas, M | 1 |
| Nooter, K | 1 |
| Sonneveld, P | 1 |
| Oostrum, R | 1 |
| Herweijer, H | 1 |
| Hagenbeek, T | 1 |
| Valerio, D | 1 |
| Adams, M | 1 |
| Duigou-Osterndorf, R | 1 |
| Godfrey, L | 1 |
| Clarkson, B | 1 |
| Andreeff, M | 1 |
| Kraft, J | 1 |
| Grille, W | 1 |
| Appelt, M | 1 |
| Hossfeld, DK | 1 |
| Eichelbaum, M | 1 |
| Koslowski, B | 1 |
| Quabeck, K | 1 |
| Kuse, R | 1 |
| Büchner, T | 1 |
| Hiddemann, W | 1 |
| McGrath, T | 1 |
| Latoud, C | 1 |
| Arnold, ST | 1 |
| Safa, AR | 1 |
| Felsted, RL | 1 |
| Center, MS | 1 |
| Maruyama, Y | 1 |
| Murohashi, I | 1 |
| Nara, N | 1 |
| Aoki, N | 1 |
| Rephaeli, A | 1 |
| Aviram, A | 1 |
| Englender, T | 1 |
| Shaklai, M | 1 |
| Yen, A | 1 |
| Freeman, L | 1 |
| Powers, V | 1 |
| Van Sant, R | 1 |
| Fishbaugh, J | 1 |
| Levy, R | 1 |
| Nathan, I | 1 |
| Barnea, E | 1 |
| Chaimovitz, C | 1 |
| Shany, S | 1 |
| Iida, H | 1 |
| Okazaki, T | 1 |
| Mochizuki, T | 1 |
| Tashima, M | 1 |
| Sawada, H | 1 |
| Uchino, H | 1 |
| Hindenburg, AA | 1 |
| Baker, MA | 1 |
| Gleyzer, E | 1 |
| Stewart, VJ | 1 |
| Case, N | 1 |
| Taub, RN | 2 |
| Bhalla, K | 1 |
| Hindenburg, A | 1 |
| Grant, S | 1 |
3 reviews available for verapamil and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
[Recent advances in the treatment of acute myelogenous leukemia: a view of the new agents].
Topics: Alkyl and Aryl Transferases; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humani | 2003 |
Multidrug resistance and stem cells in acute myeloid leukemia.
Topics: ADP-ribosyl Cyclase 1; Antigens, CD34; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Ca | 2006 |
[Trials of modulating the MDR1 phenotype in malignant hemopathies].
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Dexamethasone; Doxorubicin; D | 1994 |
3 trials available for verapamil and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Cyclosporine diminishes multidrug resistance in K562/ADM cells and improves complete remission in patients with acute myeloid leukemia.
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cass | 2009 |
[Trials of modulating the MDR1 phenotype in malignant hemopathies].
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Dexamethasone; Doxorubicin; D | 1994 |
Effects of verapamil on anthracycline-induced cardiomyopathy: preliminary results of a prospective multicenter trial.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cytarabine; Dau | 1990 |
39 other studies available for verapamil and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Reversal of P-glycoprotein-mediated MDR by 5,7,3',4',5'-pentamethoxyflavone and SAR.
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor | 2004 |
Multidrug reverting activity toward leukemia cells in a group of new verapamil analogues with low cardiovascular activity.
Topics: Adult; Aged; Aged, 80 and over; Animals; Anti-Arrhythmia Agents; Antibiotics, Antineoplastic; Aorta; | 2006 |
ABCB1 modulation does not circumvent drug extrusion from primitive leukemic progenitor cells and may preferentially target residual normal cells in acute myelogenous leukemia.
Topics: Adolescent; ADP-ribosyl Cyclase 1; Adult; Aged; Antigens, CD34; Antigens, Differentiation; ATP Bindi | 2006 |
In vitro effect of r-verapamil on acute myelogenous leukemia blast cells: studies of cytokine secretion and cytokine-dependent blast proliferation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Cell Division; Cytokines; Fema | 1995 |
Effects of dipyridamole and R-verapamil on in vitro proliferation of blast cells from patients with acute myelogenous leukaemia.
Topics: Adult; Aged; Blast Crisis; Cell Division; Dipyridamole; Dose-Response Relationship, Drug; Female; Gr | 1993 |
Flow cytometric assessment of multidrug resistance (MDR) phenotype in acute myeloid leukaemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; | 1993 |
[The use of verapamil in tests for determining the drug resistance of leukemic blasts].
Topics: Adolescent; Adult; Aged; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloi | 1993 |
P-glycoprotein and alterations in the glutathione/glutathione-peroxidase cycle underlie doxorubicin resistance in HL-60-R, a subclone of the HL-60 human leukemia cell line.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine | 1993 |
Enhancement of daunorubicin accumulation, retention, and cytotoxicity by verapamil or cyclosporin A in blast cells from patients with previously untreated acute myeloid leukemia.
Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, W | 1993 |
Flow cytometric study of idarubicin and daunorubicin accumulation and the effect of verapamil in leukemic cell lines and fresh cells from patients with acute non-lymphoblastic leukemia.
Topics: Adolescent; Adult; Daunorubicin; Drug Resistance; Female; Flow Cytometry; Humans; Idarubicin; Leukem | 1994 |
Comparative effects of racemic verapamil vs R-verapamil on normal and leukemic progenitors.
Topics: Bone Marrow Cells; Colony-Forming Units Assay; Daunorubicin; Drug Therapy, Combination; Erythroid Pr | 1993 |
Daunorubicin-induced internucleosomal DNA fragmentation in acute myeloid cell lines.
Topics: Acetylcysteine; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; ATP Binding Cassette Transport | 1996 |
Dexverapamil as resistance modifier in acute myeloid leukaemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfa | 1995 |
In vitro effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocyte activation takes place in the presence of acute myelogenous leukemia blasts.
Topics: Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Female; Granulocyte Colony-Stimulating Fac | 1996 |
Rhodamine 123 efflux modulation in the presence of low or high serum from CD56+ hematopoietic cells or CD34+ leukemic blasts by B9309-068, a newly designed pyridine derivative.
Topics: Acridines; Antigens, CD34; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cass | 1998 |
Drug concentration-dependent expression of multidrug resistance-associated protein and P-glycoprotein in the doxorubicin-resistant acute myelogenous leukemia sublines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette | 1999 |
Multidrug resistance modulation in vivo: the effect of cyclosporin A alone or with dexverapamil on idarubicin pharmacokinetics in acute leukemia.
Topics: Cyclosporine; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Idarubicin; Leukemia, My | 1999 |
Triggering noncycling hematopoietic progenitors and leukemic blasts to proliferate increases anthracycline retention and toxicity by downregulating multidrug resistance.
Topics: Antibiotics, Antineoplastic; Antigens, CD34; ATP Binding Cassette Transporter, Subfamily B, Member 1 | 1999 |
Discordance of P-glycoprotein expression and function in acute leukemia.
Topics: Adolescent; Adult; Age Factors; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow | 1999 |
In vitro effect of multidrug resistance modifiers on idarubicinol efflux in blasts of acute myeloid leukemia.
Topics: Antineoplastic Agents; Blast Crisis; Calcium Channel Blockers; Daunorubicin; Dihydropyridines; Drug | 2000 |
In vitro effect of P-glycoprotein (P-gp) modulators on drug sensitivity of leukemic progenitors (CFU-L) in acute myelogenous leukemia (AML).
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cefoperazone; Cyclosporine; Daunorub | 1992 |
Effects of a new triazinoaminopiperidine derivative on adriamycin accumulation and retention in cells displaying P-glycoprotein-mediated multidrug resistance.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Membe | 1992 |
Cytotoxicity of adriamycin, idarubicin, and vincristine in acute myeloid leukemia: chemosensitization by verapamil in relation to P-glycoprotein expression.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Membe | 1992 |
P-glycoprotein expression in refractory hematological neoplasms and circumvention of resistance with verapamil or cyclosporine A containing protocols.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, | 1992 |
Effect of dipyridamole, theophyllamine and verapamil on spontaneous in vitro proliferation of myelogenous leukaemia cells.
Topics: Aminophylline; Blast Crisis; Cell Division; Dipyridamole; Dose-Response Relationship, Drug; Drug Scr | 1992 |
Comparative cellular pharmacology of daunorubicin and idarubicin in human multidrug-resistant leukemia cells.
Topics: Cell Division; Daunorubicin; Drug Resistance; Humans; Idarubicin; Leukemia, Myeloid, Acute; Precurso | 1992 |
P-glycoprotein expression and in vitro reversion of doxorubicin resistance by verapamil in clinical specimens from acute leukaemia and myeloma.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Resistance; Humans; Leuke | 1991 |
Sufficient levels of quinine in the serum circumvent the multidrug resistance of the human leukemic cell line K562/ADM.
Topics: Doxorubicin; Drug Resistance; Feasibility Studies; Humans; Leukemia; Leukemia, Myeloid, Acute; Multi | 1991 |
Overexpression of the mdr1 gene in blast cells from patients with acute myelocytic leukemia is associated with decreased anthracycline accumulation that can be restored by cyclosporin-A.
Topics: Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporins; Daun | 1990 |
Effect of tamoxifen on cell lines displaying the multidrug-resistant phenotype.
Topics: Cell Division; Daunorubicin; Drug Resistance; Flow Cytometry; Humans; Kinetics; Leukemia, Lymphoid; | 1991 |
Mechanisms of multidrug resistance in HL60 cells. Analysis of resistance associated membrane proteins and levels of mdr gene expression.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Resistance; Gene Amplific | 1989 |
Effects of verapamil on the cellular accumulation of daunorubicin in blast cells and on the chemosensitivity of leukaemic blast progenitors in acute myelogenous leukaemia.
Topics: Adult; Aged; Cell Survival; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia | 1989 |
Differentiation-associated changes of cation-transport activities in myeloid leukemic cell lines.
Topics: Amiloride; Biological Transport; Calcium; Carrier Proteins; Cell Differentiation; Cromolyn Sodium; H | 1988 |
Cell cycle dependence of calmodulin levels during HL-60 proliferation and myeloid differentiation. No changes during pre-commitment.
Topics: Calmodulin; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Humans; Leukemia, Myeloid, A | 1986 |
The involvement of calcium ions in the effect of 1,25-dihydroxyvitamin D3 on HL-60 cells.
Topics: Calcitriol; Calcium; Cell Differentiation; Cell Line; Cytosol; Egtazic Acid; Growth Inhibitors; Huma | 1988 |
Effects of cytochalasins and colchicine on the accumulation and retention of daunomycin and vincristine in drug resistant tumor cells.
Topics: Animals; Cell Line; Cell Survival; Colchicine; Cytochalasin B; Cytochalasin D; Cytochalasins; Daunor | 1986 |
Role of intracellular calcium ion in human promyelocytic leukemia HL-60 cell differentiation.
Topics: Calcitriol; Calcium; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Ethers; Gal | 1986 |
Effect of verapamil and other agents on the distribution of anthracyclines and on reversal of drug resistance.
Topics: Antibiotics, Antineoplastic; Cell Line; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Leukemia | 1987 |
Isolation and characterization of an anthracycline-resistant human leukemic cell line.
Topics: Antibiotics, Antineoplastic; Cell Differentiation; Cell Line; Drug Resistance; Glycoproteins; Humans | 1985 |