verapamil has been researched along with Leukemia, Lymphocytic in 15 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leukemic cells isolated from peripheral blood from 6 patients with chronic lymphocytic leukemia, immunocytoma and prolymphocytic leukemia were incubated with vincristine (10 nM) with and without racemic verapamil and its L- and D-isomers (6." | 3.67 | D-verapamil and L-verapamil are equally effective in increasing vincristine accumulation in leukemic cells in vitro. ( Gruber, A; Peterson, C; Reizenstein, P, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (60.00) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beck, WT | 4 |
| Galimberti, S | 1 |
| Bianchi, F | 1 |
| Bernardini, N | 1 |
| Mattii, L | 1 |
| Dolfi, A | 1 |
| Lupetti, M | 1 |
| Petrini, M | 1 |
| Syed, SK | 1 |
| Christopherson, RI | 1 |
| Roufogalis, BD | 1 |
| Shepard, RL | 1 |
| Winter, MA | 1 |
| Hsaio, SC | 1 |
| Pearce, HL | 1 |
| Dantzig, AH | 1 |
| Warren, L | 1 |
| Jardillier, JC | 1 |
| Ordentlich, P | 1 |
| Berman, E | 1 |
| Adams, M | 1 |
| Duigou-Osterndorf, R | 1 |
| Godfrey, L | 1 |
| Clarkson, B | 1 |
| Andreeff, M | 1 |
| Hu, XF | 1 |
| Martin, TJ | 1 |
| Bell, DR | 1 |
| de Luise, M | 1 |
| Zalcberg, JR | 1 |
| Hibasami, H | 1 |
| Maekawa, S | 1 |
| Murata, T | 1 |
| Nakashima, K | 1 |
| Cass, CE | 1 |
| Janowska-Wieczorek, A | 1 |
| Lynch, MA | 1 |
| Sheinin, H | 1 |
| Hindenburg, AA | 1 |
| Vayuvegula, B | 1 |
| Slater, L | 1 |
| Meador, J | 1 |
| Gupta, S | 1 |
| Gruber, A | 1 |
| Peterson, C | 1 |
| Reizenstein, P | 1 |
| Slater, LM | 1 |
| Murray, SL | 1 |
| Wetzel, MW | 1 |
| Sweet, P | 1 |
| Stupecky, M | 1 |
| Cirtain, MC | 1 |
| Look, AT | 1 |
| Ashmun, RA | 1 |
| Weisenthal, LM | 1 |
| Su, YZ | 1 |
| Duarte, TE | 1 |
| Dill, PL | 1 |
| Nagourney, RA | 1 |
| Vietti Ramus, G | 1 |
| Cesano, L | 1 |
| Barbalonga, A | 1 |
| Pallisco, O | 1 |
15 other studies available for verapamil and Leukemia, Lymphocytic
| Article | Year |
|---|---|
Cellular pharmacology of Vinca alkaloid resistance and its circumvention.
Topics: Biological Transport, Active; Cell Line; Cell Survival; Drug Resistance; Fluphenazine; Glucose; Huma | 1984 |
Scanning electron microscopy of multidrug resistant cells in haematological and mammary malignancies.
Topics: Acute Disease; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Breas | 1993 |
Vinblastine transport by membrane vesicles from human multidrug-resistant CCRF-CEM leukaemia cells: inhibition by taxol and membrane permeabilising agents.
Topics: Alamethicin; Cell Membrane; Cell Membrane Permeability; Drug Resistance; Humans; Leukemia, Lymphoid; | 1993 |
Effect of modulators on the ATPase activity and vanadate nucleotide trapping of human P-glycoprotein.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; ATP Binding Ca | 1998 |
Secretion of lysosomal enzymes by drug-sensitive and multiple drug-resistant cells.
Topics: Acetylglucosaminidase; Acid Phosphatase; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dr | 1991 |
Effect of tamoxifen on cell lines displaying the multidrug-resistant phenotype.
Topics: Cell Division; Daunorubicin; Drug Resistance; Flow Cytometry; Humans; Kinetics; Leukemia, Lymphoid; | 1991 |
Combined use of cyclosporin A and verapamil in modulating multidrug resistance in human leukemia cell lines.
Topics: Cyclosporins; DNA, Neoplasm; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Drug | 1990 |
Inhibition by polyamines of methylthiopropylamine-induced ornithine decarboxylase in human lymphoid leukemia Molt 4B cells.
Topics: Cell Line; Enzyme Induction; Humans; Leukemia, Lymphoid; Nifedipine; Ornithine Decarboxylase; Ornith | 1989 |
Effect of duration of exposure to verapamil on vincristine activity against multidrug-resistant human leukemic cell lines.
Topics: Cell Division; Cell Line; Drug Resistance; Humans; Kinetics; Leukemia, Lymphoid; Leukemia, Promyeloc | 1989 |
Correction of altered plasma membrane potentials. A possible mechanism of cyclosporin A and verapamil reversal of pleiotropic drug resistance in neoplasia.
Topics: Animals; Antineoplastic Agents; Calcium; Cell Line; Cell Membrane; Cyclosporins; Drug Resistance; Le | 1988 |
D-verapamil and L-verapamil are equally effective in increasing vincristine accumulation in leukemic cells in vitro.
Topics: Calcium; Drug Resistance; Humans; Leukemia; Leukemia, Lymphoid; Leukocytes; Lymphoma; Stereoisomeris | 1988 |
Verapamil potentiation of VP-16-213 in acute lymphatic leukemia and reversal of pleiotropic drug resistance.
Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Daunorubicin; Dose-Response Relation | 1986 |
Reversal of Vinca alkaloid resistance but not multiple drug resistance in human leukemic cells by verapamil.
Topics: Cell Cycle; Cell Line; Cell Survival; Daunorubicin; Doxorubicin; Drug Resistance; Drug Synergism; Fl | 1986 |
Perturbation of in vitro drug resistance in human lymphatic neoplasms by combinations of putative inhibitors of protein kinase C.
Topics: Cell Survival; Chlorpromazine; Drug Resistance; Drug Synergism; Haloperidol; Humans; Imipramine; In | 1987 |
[ Action of low doses of vincristine, lidocaine and verapamil on DNA replication in vitro].
Topics: Adult; Aged; Cells, Cultured; Culture Media; DNA Replication; Doxorubicin; Drug Combinations; Female | 1986 |